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Diseases such as diabetic retinopathy and age-related macular degeneration pose a significant risk to vision, highlighting the importance of precise segmentation of retinal vessels for the tracking and diagnosis of progression. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Tariq M. Khan , Muhammad Arsalan , Shahzaib Iqbal , Imran Razzak , Erik Meijering

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Domain-generalized retinal vessel segmentation is critical for automated ophthalmic diagnosis, yet faces significant challenges from domain shift induced by non-uniform illumination and varying contrast, compounded by the difficulty of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Chanchan Wang , Yuanfang Wang , Qing Xu , Guanxin Chen

Computer-Aided Diagnosis systems are required to extract suitable information about retina and its changes. In particular, identifying objects of interest such as lesions and anatomical structures from the retinal images is a challenging…

Medical Physics · Physics 2020-05-20 Meysam Tavakoli , Mahdieh Nazar , Alireza Mehdizadeh

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen

Optical coherence tomography angiography (OCTA) is a noninvasive imaging technique that can reveal high-resolution retinal vessels. In this work, we propose an accurate and efficient neural network for retinal vessel segmentation in OCTA…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Haojian Ning , Chengliang Wang , Xinrun Chen , Shiying Li

Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Gorana Gojić , Veljko Petrović , Radovan Turović , Dinu Dragan , Ana Oros , Dušan Gajić , Nebojša Horvat

Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sharan SK , Subin Sahayam , Umarani Jayaraman , Lakshmi Priya A

The vascular structure of blood vessels is important in diagnosing retinal conditions such as glaucoma and diabetic retinopathy. Accurate segmentation of these vessels can help in detecting retinal objects such as the optic disc and optic…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Abdullah Sarhan , Jon Rokne , Reda Alhajj , Andrew Crichton

Experts use retinal images and vessel trees to detect and diagnose various eye, blood circulation, and brain-related diseases. However, manual segmentation of retinal images is a time-consuming process that requires high expertise and is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Alnur Alimanov , Md Baharul Islam

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Retinal vessel segmentation is a fundamental step in screening, diagnosis, and treatment of various cardiovascular and ophthalmic diseases. Robustness is one of the most critical requirements for practical utilization, since the test images…

Image and Video Processing · Electrical Eng. & Systems 2021-09-29 Xu Sun , Huihui Fang , Yehui Yang , Dongwei Zhu , Lei Wang , Junwei Liu , Yanwu Xu

Abnormalities in retinal fundus images may indicate certain pathologies such as diabetic retinopathy, hypertension, stroke, glaucoma, retinal macular edema, venous occlusion, and atherosclerosis, making the study and analysis of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Yuzhuo Chen , Zetong Chen , Yuanyuan Liu

Optical coherence tomography angiography (OCTA) can non-invasively image the eye's circulatory system. In order to reliably characterize the retinal vasculature, there is a need to automatically extract quantitative metrics from these…

Image and Video Processing · Electrical Eng. & Systems 2022-07-25 Martin J. Menten , Johannes C. Paetzold , Alina Dima , Bjoern H. Menze , Benjamin Knier , Daniel Rueckert

Accurate retinal vessel segmentation is challenging because of the complex texture of retinal vessels and low imaging contrast. Previous methods generally refine segmentation results by cascading multiple deep networks, which are…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Mingxing Li , Shenglong Zhou , Chang Chen , Yueyi Zhang , Dong Liu , Zhiwei Xiong

Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker

Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

Accurate detection of retinal vessels plays a critical role in reflecting a wide range of health status indicators in the clinical diagnosis of ocular diseases. Recently, advances in deep learning have led to a surge in retinal vessel…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Jiawen Liu , Yuanbo Zeng , Jiaming Liang , Yizhen Yang , Yiheng Zhang , Enhui Cai , Xiaoqi Sheng , Hongmin Cai

Tight-frame, a generalization of orthogonal wavelets, has been used successfully in various problems in image processing, including inpainting, impulse noise removal, super-resolution image restoration, etc. Segmentation is the process of…

Numerical Analysis · Mathematics 2015-03-19 Xiaohao Cai , Raymond Chan , Serena Morigi , Fiorella Sgallari