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During the first wave of COVID-19, hospitals were overwhelmed with the high number of admitted patients. An accurate prediction of the most likely individual disease progression can improve the planning of limited resources and finding the…

Accurately predicting hospital readmission risks using electronic health records (EHRs) is critical for effective patient management and healthcare resource allocation. Patient populations in health systems are highly heterogeneous across…

Background: Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in…

Machine Learning · Computer Science 2024-09-04 Armin Abdollahi , Negin Ashrafi , Maryam Pishgar

Timely transition from intravenous (IV) to oral antibiotic therapy shortens hospital stays, reduces catheter-related infections, and lowers healthcare costs, yet one in five patients in England remain on IV antibiotics despite meeting…

Machine Learning · Computer Science 2026-03-10 Magnus Ross , Nel Swanepoel , Akish Luintel , Emma McGuire , Ingemar J. Cox , Steve Harris , Vasileios Lampos

Hospital readmission prediction is critical for clinical decision support, aiming to identify patients at risk of returning within 30 days post-discharge. High readmission rates often indicate inadequate treatment or post-discharge care,…

Machine Learning · Computer Science 2024-12-18 Zhenyi Fan , Jiaqi Li , Dongyu Luo , Yuqi Yuan

Introduction: Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays, with planned admissions being safer than unplanned ones. However, post-operative care decisions remain subjective. This…

Background: Invasive coronary arteriography (ICA) is recognized as the gold standard for diagnosing cardiovascular diseases, including unstable angina (UA). The challenge lies in determining the optimal timing for ICA in UA patients,…

Machine Learning · Computer Science 2024-08-09 Candi Zheng , Kun Liu , Yang Wang , Shiyi Chen , Hongli Li

Hospital readmission is a crucial healthcare quality measure that helps in determining the level of quality of care that a hospital offers to a patient and has proven to be immensely expensive. It is estimated that more than $25 billion are…

Machine Learning · Computer Science 2020-02-27 Sarthak , Shikhar Shukla , Surya Prakash Tripathi

Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the…

Machine Learning · Computer Science 2017-07-18 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

Objective: Clinical notes contain information not present elsewhere, including drug response and symptoms, all of which are highly important when predicting key outcomes in acute care patients. We propose the automatic annotation of…

Computation and Language · Computer Science 2021-11-25 Jingqing Zhang , Luis Bolanos , Ashwani Tanwar , Julia Ive , Vibhor Gupta , Yike Guo

We present Clinical Prediction with Large Language Models (CPLLM), a method that involves fine-tuning a pre-trained Large Language Model (LLM) for clinical disease and readmission prediction. We utilized quantization and fine-tuned the LLM…

Computation and Language · Computer Science 2024-05-03 Ofir Ben Shoham , Nadav Rappoport

An increasing amount of research is being devoted to applying machine learning methods to electronic health record (EHR) data for various clinical purposes. This growing area of research has exposed the challenges of the accessibility of…

Machine Learning · Computer Science 2022-12-22 Mehak Gupta , Brennan Gallamoza , Nicolas Cutrona , Pranjal Dhakal , Raphael Poulain , Rahmatollah Beheshti

Accurate patient mortality prediction enables effective risk stratification, leading to personalized treatment plans and improved patient outcomes. However, predicting mortality in healthcare remains a significant challenge, with existing…

Machine Learning · Computer Science 2025-03-28 HyeYoung Lee , Pavel Tsoi

Sepsis is a leading cause of mortality in intensive care units (ICUs) and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and…

Machine Learning · Computer Science 2017-05-24 Aniruddh Raghu , Matthieu Komorowski , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Continuous monitoring and patient acuity assessments are key aspects of Intensive Care Unit (ICU) practice, but both are limited by time constraints imposed on healthcare providers. Moreover, anticipating clinical trajectories remains…

While image analysis of chest computed tomography (CT) for COVID-19 diagnosis has been intensively studied, little work has been performed for image-based patient outcome prediction. Management of high-risk patients with early intervention…

Hyperkalemia is a potentially life-threatening condition that can lead to fatal arrhythmias. Early identification of high risk patients can inform clinical care to mitigate the risk. While hyperkalemia is often a complication of acute…

Machine Learning · Computer Science 2021-01-28 Gloria Hyunjung Kwak , Christina Chen , Lowell Ling , Erina Ghosh , Leo Anthony Celi , Pan Hui

Background: During the early stages of hospital admission, clinicians must use limited information to make diagnostic and treatment decisions as patient acuity evolves. However, it is common that the time series vital sign information from…

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

Machine Learning · Computer Science 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

Survival analysis is central to clinical research, informing patient prognoses, guiding treatment decisions, and optimising resource allocation. Accurate time-to-event predictions not only improve quality of life but also reveal risk…