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In treating gastrointestinal cancer using radiotherapy, the role of the radiation oncologist is to administer high doses of radiation, through x-ray beams, toward the tumor while avoiding the stomach and intestines. With the advent of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Kai Li , Jonathan Chan

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

Medical imaging contains the essential information for rendering diagnostic and treatment decisions. Inspecting (visual perception) and interpreting image to generate a report are tedious clinical routines for a radiologist where automation…

Computer Vision and Pattern Recognition · Computer Science 2020-06-01 Xin Li , Rui Cao , Dongxiao Zhu

Nowadays Artificial Intelligence (AI) has become a fundamental component of healthcare applications, both clinical and remote, but the best performing AI systems are often too complex to be self-explaining. Explainable AI (XAI) techniques…

Machine Learning · Computer Science 2022-09-15 Flavio Di Martino , Franca Delmastro

Background & Purpose: Chest X-Ray (CXR) use in pre-MRI safety screening for Lead-Less Implanted Electronic Devices (LLIEDs), easily overlooked or misidentified on a frontal view (often only acquired), is common. Although most LLIED types…

Image and Video Processing · Electrical Eng. & Systems 2022-04-28 Mutlu Demirer , Richard D. White , Vikash Gupta , Ronnie A. Sebro , Barbaros S. Erdal

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Chest X-ray (CXR) plays a pivotal role in clinical diagnosis, and a variety of task-specific and foundation models have been developed for automatic CXR interpretation. However, these models often struggle to adapt to new diagnostic tasks…

Artificial Intelligence · Computer Science 2025-10-27 Jinhui Lou , Yan Yang , Zhou Yu , Zhenqi Fu , Weidong Han , Qingming Huang , Jun Yu

Agentic systems offer a potential path to solve complex clinical tasks through collaboration among specialized agents, augmented by tool use and external knowledge bases. Nevertheless, for chest X-ray (CXR) interpretation, prevailing…

Multiagent Systems · Computer Science 2026-04-16 Kai Zhang , Corey D Barrett , Jangwon Kim , Lichao Sun , Tara Taghavi , Krishnaram Kenthapadi

The escalating demand for medical image interpretation underscores the critical need for advanced artificial intelligence solutions to enhance the efficiency and accuracy of radiological diagnoses. This paper introduces CXR-PathFinder, a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Pimchanok Sukjai , Apiradee Boonmee

It is imperative that breast cancer is detected precisely and timely to improve patient outcomes. Diagnostic methodologies have traditionally relied on unimodal approaches; however, medical data analytics is integrating diverse data sources…

Machine Learning · Computer Science 2024-06-21 Faseela Abdullakutty , Younes Akbari , Somaya Al-Maadeed , Ahmed Bouridane , Rifat Hamoudi

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

Advancements in deep learning have enabled highly accurate arrhythmia detection from electrocardiogram (ECG) signals, but limited interpretability remains a barrier to clinical adoption. This study investigates the application of…

Machine Learning · Computer Science 2025-08-26 Joschka Beck , Arlene John

The continuous development of artificial intelligence (AI) theory has propelled this field to unprecedented heights, owing to the relentless efforts of scholars and researchers. In the medical realm, AI takes a pivotal role, leveraging…

Machine Learning · Computer Science 2024-12-04 Qiyang Sun , Alican Akman , Björn W. Schuller

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

Black-box nature of Artificial Intelligence (AI) models do not allow users to comprehend and sometimes trust the output created by such model. In AI applications, where not only the results but also the decision paths to the results are…

Artificial Intelligence · Computer Science 2024-10-28 Ibrahim Kok , Feyza Yildirim Okay , Ozgecan Muyanli , Suat Ozdemir

Artificial intelligence (AI) systems have substantially improved dermatologists' diagnostic accuracy for melanoma, with explainable AI (XAI) systems further enhancing clinicians' confidence and trust in AI-driven decisions. Despite these…

The application of deep learning in medical imaging has significantly advanced diagnostic capabilities, enhancing both accuracy and efficiency. Despite these benefits, the lack of transparency in these AI models, often termed "black boxes,"…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Eleonora Beatrice Rossi , Eleonora Lopez , Danilo Comminiello

Radiology reports are detailed text descriptions of the content of medical scans. Each report describes the presence/absence and location of relevant clinical findings, commonly including comparison with prior exams of the same patient to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Francesco Dalla Serra , Chaoyang Wang , Fani Deligianni , Jeffrey Dalton , Alison Q O'Neil

Artificial Intelligence (AI) has become essential for analyzing complex data and solving highly-challenging tasks. It is being applied across numerous disciplines beyond computer science, including Food Engineering, where there is a growing…

Gastric endoscopic screening is an effective way to decide appropriate gastric cancer (GC) treatment at an early stage, reducing GC-associated mortality rate. Although artificial intelligence (AI) has brought a great promise to assist…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Yujin Oh , Go Eun Bae , Kyung-Hee Kim , Min-Kyung Yeo , Jong Chul Ye