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All-atom dynamics simulations are an indispensable quantitative tool in physics, chemistry, and materials science, but large systems and long simulation times remain challenging due to the trade-off between computational efficiency and…

Materials Science · Physics 2024-03-21 Stephen R. Xie , Matthias Rupp , Richard G. Hennig

Hydrogen atom transfer (HAT) reactions are essential in many biological processes, such as radical migration in damaged proteins, but their mechanistic pathways remain incompletely understood. Simulating HAT is challenging due to the need…

Machine Learning · Computer Science 2025-11-25 Marlen Neubert , Patrick Reiser , Frauke Gräter , Pascal Friederich

Transition metal oxides belong to a genre of quantum materials essential for the exploration of theoretical methods for quantifying electronic correlation. Finding an efficient and accurate first principles method for the assertion of such…

Materials Science · Physics 2025-08-13 Suvadip Das

Over the past decade inter-atomic potentials based on machine-learning (ML) techniques have become an indispensable tool in the atomic-scale modeling of materials. Trained on energies and forces obtained from electronic-structure…

Materials Science · Physics 2022-08-15 Michele Ceriotti

We propose a methodology to generate hybrid machine learning models for the potential energy surface trained simultaneously on data from ab initio electronic structure calculations and on thermodynamic and/or structural observables from…

Statistical Mechanics · Physics 2025-11-19 Pablo Peña-Cano , Pablo M. Piaggi

New refractory alloys are being continuously designed and characterised for applications requiring good high-temperature mechanical properties and stability. Computational design from atomistic simulations is limited by interatomic…

Materials Science · Physics 2026-03-05 Jesper Byggmästar , Tiago Lopes , Zheyong Fan , Tapio Ala-Nissila

This work proposes a hybrid modeling framework based on recurrent neural networks (RNNs) and the finite element (FE) method to approximate model discrepancies in time dependent, multi-fidelity problems, and use the trained hybrid models to…

Computational Engineering, Finance, and Science · Computer Science 2024-02-20 Moritz von Tresckow , Herbert De Gersem , Dimitrios Loukrezis

Solvent environments play a central role in determining molecular structure, energetics, reactivity, and interfacial phenomena. However, modeling solvation from first principles remains difficult due to the complex interplay of interactions…

Chemical Physics · Physics 2026-01-05 Roopshree Banchode , Surajit Das , Shampa Raghunathan , Raghunathan Ramakrishnan

To operate process engineering systems in a safe and reliable manner, predictive models are often used in decision making. In many cases, these are mechanistic first principles models which aim to accurately describe the process. In…

Machine Learning · Computer Science 2022-05-20 Timur Bikmukhametov , Johannes Jäschke

The extent of ion pairing in solution is an important phenomenon to rationalise transport and thermodynamic properties of electrolytes. A fundamental measure of this pairing is the potential of mean force (PMF) between solvated ions. The…

Chemical Physics · Physics 2024-04-11 Niamh O'Neill , Benjamin X. Shi , Kara Fong , Angelos Michaelides , Christoph Schran

In modern generative-AI workloads, matrix-vector/matrix-matrix multiplications (\emph{MatMul}) dominate the compute and energy cost. Achieving dramatic reductions in energy per token therefore requires a novel, specialized hardware that is…

Other Condensed Matter · Physics 2026-03-11 Denis Mamaluy , Md Rahatul Islam Udoy , Juan P. Mendez , Ben Feinberg , Wei Pan , Ahmedullah Aziz

While a big wave of artificial intelligence (AI) has propagated to the field of computational fluid dynamics (CFD) acceleration studies, recent research has highlighted that the development of AI techniques that reconciles the following…

Fluid Dynamics · Physics 2023-11-28 Joongoo Jeon , Juhyeong Lee , Ricardo Vinuesa , Sung Joong Kim

Data scarcity, bias, and experimental noise are all frequently encountered problems in the application of deep learning to chemical and material science disciplines. Transfer learning has proven effective in compensating for the lack in…

Chemical Physics · Physics 2021-03-16 Florence H. Vermeire , William H. Green

Accurately predicting chemical reaction outcomes and potential byproducts is a fundamental task of modern chemistry, enabling the efficient design of synthetic pathways and driving progress in chemical science. Reaction mechanism, which…

Chemical Physics · Physics 2025-03-14 Shuan Chen , Kye Sung Park , Taewan Kim , Sunkyu Han , Yousung Jung

The increasing demand for materials capable of withstanding high temperatures and harsh environments necessitates the discovery of advanced alloys. This study introduces a computational routine to predict solid-state phase stability and…

Materials Science · Physics 2025-07-29 Tyler D. Doležal , Nick A. Valverde , Jodie Yuwono , Ryan Kemnitz

Materials composed of elements from the third and fifth columns of the periodic table display a very rich behavior, with the phase diagram usually containing a metallic liquid phase and a polar semiconducting solid. As a consequence, it is…

Materials Science · Physics 2022-01-13 Giulio imbalzano , Michele Ceriotti

Understanding and accurately predicting hydrogen diffusion in materials is challenging due to the complex interactions between hydrogen defects and the crystal lattice. These interactions span large length and time scales, making them…

Laboratory and numerical corrosion experiments impose an electric potential on the metal surface, differing from natural corrosion conditions, where corrosion typically occurs in the absence of external current sources. In this work, we…

Chemical Physics · Physics 2023-05-23 Tim Hageman , Carmen Andrade , Emilio Martínez-Pañeda

Machine learning (ML) models are often constrained by their limitations in extrapolation, which restricts their applicability in engineering contexts. Conversely, while exhibiting broad generality, many established scientific models seem to…

Fluid Dynamics · Physics 2025-09-23 Hanying Yang , James C. Massey , Nedunchezhian Swaminathan

Machine Learning Potentials (MLPs) can enable simulations of ab initio accuracy at orders of magnitude lower computational cost. However, their effectiveness hinges on the availability of considerable datasets to ensure robust…

Machine Learning · Computer Science 2025-02-20 Sebastien Röcken , Julija Zavadlav