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We address the problem of parameter identification for the standard pharmacokinetic/pharmacodynamic (PK/PD) model for anesthetic drugs. Our main contribution is the development of a global optimization method that guarantees finding the…

Systems and Control · Electrical Eng. & Systems 2025-03-20 Giulia Di Credico , Luca Consolini , Mattia Laurini , Marco Locatelli , Marco Milanesi , Michele Schiavo , Antonio Visioli

Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

This study develops a cloud-based deep learning system for early prediction of diabetes, leveraging the distributed computing capabilities of the AWS cloud platform and deep learning technologies to achieve efficient and accurate risk…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-07 Yang Zhang , Fa Wang , Xin Huang , Xintao Li , Sibei Liu , Hansong Zhang

Medication recommender is to suggest appropriate medication combinations based on a patient's health history, e.g., diagnoses and procedures. Existing works represent different diagnoses/procedures well separated by one-hot encodings.…

Information Retrieval · Computer Science 2024-11-06 Yuliang Liang , Yuting Liu , Yizhou Dang , Enneng Yang , Guibing Guo , Wei Cai , Jianzhe Zhao , Xingwei Wang

We propose a transformer architecture for time series forecasting with a focus on time series tokenisation and apply it to a real-world prediction problem from the pricing domain. Our architecture aims to learn effective representations at…

Machine Learning · Computer Science 2025-04-22 Egon Peršak , Miguel F. Anjos , Sebastian Lautz , Aleksandar Kolev

The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

Machine Learning · Computer Science 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

In machine learning, effective modeling requires a holistic consideration of how to encode inputs, make predictions (i.e., decoding), and train the model. However, in time-series forecasting, prior work has predominantly focused on encoder…

Machine Learning · Computer Science 2025-12-30 Jaebin Lee , Hankook Lee

The availability of continuous glucose monitors as over-the-counter commodities have created a unique opportunity to monitor a person's blood glucose levels, forecast blood glucose trajectories and provide automated interventions to prevent…

Machine Learning · Computer Science 2026-04-16 Ebrahim Farahmand , Shovito Barua Soumma , Nooshin Taheri Chatrudi , Hassan Ghasemzadeh

Precision medicine requires the precision disease risk prediction models. In literature, there have been a lot well-established (inter-)national risk models, but when applying them into the local population, the prediction performance…

Artificial Intelligence · Computer Science 2017-08-01 Jing Mei , Eryu Xia , Xiang Li , Guotong Xie

Academic advances of AI models in high-precision domains, like healthcare, need to be made explainable in order to enhance real-world adoption. Our past studies and ongoing interactions indicate that medical experts can use AI systems with…

Progress in the biomedical field through the use of deep learning is hindered by the lack of interpretability of the models. In this paper, we study the RETAIN architecture for the forecasting of future glucose values for diabetic people.…

Machine Learning · Computer Science 2020-09-11 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

In this work, we explore the integration of Sequence Encoding for Online Parameter Identification with Physics-Informed Neural Networks to create a model that, once trained, can be utilized for real time applications with variable…

Machine Learning · Computer Science 2025-08-25 Mouad Elaarabi , Domenico Borzacchiello , Philippe Le Bot , Nathan Lauzeral , Sebastien Comas-Cardona

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

Depth estimation from a single image is an important task that can be applied to various fields in computer vision, and has grown rapidly with the development of convolutional neural networks. In this paper, we propose a novel structure and…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Doyeon Kim , Woonghyun Ka , Pyungwhan Ahn , Donggyu Joo , Sehwan Chun , Junmo Kim

Research in diabetes, especially when it comes to building data-driven models to forecast future glucose values, is hindered by the sensitive nature of the data. Because researchers do not share the same data between studies, progress is…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Nowadays, time series forecasting is predominantly approached through the end-to-end training of deep learning architectures using error-based objectives. While this is effective at minimizing average loss, it encourages the encoder to…

Machine Learning · Computer Science 2026-03-26 Jiacheng Wang , Liang Fan , Baihua Li , Luyan Zhang

The Prognostics and Health Management Data Challenge (PHM) 2016 tracks the health state of components of a semiconductor wafer polishing process. The ultimate goal is to develop an ability to predict the measurement on the wafer surface…

Artificial Intelligence · Computer Science 2025-03-04 Kart-Leong Lim , Rahul Dutta

In healthcare, applying deep learning models to electronic health records (EHRs) has drawn considerable attention. EHR data consist of a sequence of medical visits, i.e. a multivariate time series of diagnosis, medications, physical…

Machine Learning · Computer Science 2018-10-19 Jing Mei , Shiwan Zhao , Feng Jin , Eryu Xia , Haifeng Liu , Xiang Li

Electronic Health Records (EHR) have been heavily used in modern healthcare systems for recording patients' admission information to hospitals. Many data-driven approaches employ temporal features in EHR for predicting specific diseases,…

Machine Learning · Computer Science 2021-12-07 Chang Lu , Chandan K. Reddy , Yue Ning

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li