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Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

This research paper investigates the application of Large Language Models (LLMs) in healthcare, specifically focusing on enhancing medical decision support through Retrieval-Augmented Generation (RAG) integrated with hospital-specific data…

Computation and Language · Computer Science 2025-05-07 Mohammad Shoaib Ansari , Mohd Sohail Ali Khan , Shubham Revankar , Aditya Varma , Anil S. Mokhade

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Large Language Models (LLMs) have grown exponentially since the release of ChatGPT. These models have gained attention due to their robust performance on various tasks, including language processing tasks. These models achieve understanding…

Computation and Language · Computer Science 2025-08-11 Ali Sarabadani , Maryam Abdollahi Shamami , Hamidreza Sadeghsalehi , Borhan Asadi , Saba Hesaraki

Automated radiology report generation holds significant potential to reduce radiologists' workload and enhance diagnostic accuracy. However, generating precise and clinically meaningful reports from chest radiographs remains challenging due…

Image and Video Processing · Electrical Eng. & Systems 2026-05-20 Md. Zihad Bin Jahangir , Muhammad Ashad Kabir , Sumaiya Akter , Israt Jahan , Minh Chau

Recent advancements in large language models (LLMs) like ChatGPT and LLaMA show promise in medical applications, yet challenges remain in medical language comprehension. This study presents Me-LLaMA, a new medical LLM family based on…

The application of large language models (LLMs) to healthcare information extraction has emerged as a promising approach. This study evaluates the classification performance of five open-source LLMs: GEMMA-3-27B-IT, LLAMA3-70B, LLAMA4-109B,…

Computation and Language · Computer Science 2025-05-09 Yuting Guo , Abeed Sarker

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Diagnosis-Related Group (DRG) codes are essential for hospital reimbursement and operations but require labor-intensive assignment. Large Language Models (LLMs) struggle with DRG coding due to the out-of-distribution (OOD) nature of the…

Machine Learning · Computer Science 2025-10-16 Hanyin Wang , Zhenbang Wu , Gururaj Kolar , Hariprasad Korsapati , Brian Bartlett , Bryan Hull , Jimeng Sun

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Large Language Models (LLMs) demonstrate remarkable capabilities but remain limited by their reliance on static training data. Retrieval-Augmented Generation (RAG) addresses this constraint by retrieving external knowledge during inference,…

Computation and Language · Computer Science 2026-02-19 Xingda Lyu , Gongfu Lyu , Zitai Yan , Yuxin Jiang

Accurate prediction of functional outcomes after acute ischemic stroke can inform clinical decision-making and resource allocation. Prior work on modified Rankin Scale (mRS) prediction has relied primarily on structured variables (e.g.,…

Large Language Models (LLMs) such as GPT-4 and LLaMA have demonstrated remarkable reasoning abilities but require significant computational resources for fine-tuning. This paper presents a resource-efficient fine-tuning approach for…

Computation and Language · Computer Science 2025-10-07 Imran Mansha

Despite significant advancements in adapting Large Language Models (LLMs) for radiology report generation (RRG), clinical adoption remains challenging due to difficulties in accurately mapping pathological and anatomical features to their…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Qilong Xing , Zikai Song , Youjia Zhang , Na Feng , Junqing Yu , Wei Yang

Drug discovery is a complex and resource-intensive process, making early prediction of approval outcomes critical for optimizing research investments. While classical machine learning and deep learning methods have shown promise in drug…

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

While Large Language Models (LLMs) have shown strong performance on clinical text understanding, they struggle with longitudinal prediction tasks such as dementia prognosis, which require reasoning over complex, non-monotonic symptom…

Computation and Language · Computer Science 2026-03-23 Choonghan Kim , Hyunmin Hwang , Hangeol Chang , Jaemin Kim , Jinse Park , Jae-Sung Lim , Jong Chul Ye

Large Language Models (LLMs) are increasingly adopted as evaluators, offering a scalable alternative to human annotation. However, existing supervised fine-tuning (SFT) approaches often fall short in domains that demand complex reasoning.…

Computation and Language · Computer Science 2025-11-04 Nuo Chen , Zhiyuan Hu , Qingyun Zou , Jiaying Wu , Qian Wang , Bryan Hooi , Bingsheng He
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