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Despite the rapid development of AI models in medical image analysis, their validation in real-world clinical settings remains limited. To address this, we introduce a generic framework designed for deploying image-based AI models in such…

Background: Deep neural networks have proven to be powerful computational tools for modeling, prediction, and generation. However, the workings of these models have generally been opaque. Recent work has shown that the performance of some…

Artificial Intelligence · Computer Science 2023-11-21 Andrew S. Nencka , L. Tugan Muftuler , Peter LaViolette , Kevin M. Koch

Foundation models are used for many real-world applications involving language generation from temporally-ordered multimodal events. In this work, we study the ability of models to identify the most important sub-events in a video, which is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Aditya K Surikuchi , Raquel Fernández , Sandro Pezzelle

Foundation models are premised on the idea that sequence prediction can uncover deeper domain understanding, much like how Kepler's predictions of planetary motion later led to the discovery of Newtonian mechanics. However, evaluating…

Machine Learning · Computer Science 2025-12-30 Keyon Vafa , Peter G. Chang , Ashesh Rambachan , Sendhil Mullainathan

Deep neural networks (DNN) have achieved unprecedented performance in computer-vision tasks almost ubiquitously in business, technology, and science. While substantial efforts are made to engineer highly accurate architectures and provide…

Image and Video Processing · Electrical Eng. & Systems 2022-09-08 Sumedha Singla

Foundation model, which is pre-trained on broad data and is able to adapt to a wide range of tasks, is advancing healthcare. It promotes the development of healthcare artificial intelligence (AI) models, breaking the contradiction between…

Computers and Society · Computer Science 2024-04-05 Yuting He , Fuxiang Huang , Xinrui Jiang , Yuxiang Nie , Minghao Wang , Jiguang Wang , Hao Chen

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Concept-based Models are a class of inherently explainable networks that improve upon standard Deep Neural Networks by providing a rationale behind their predictions using human-understandable `concepts'. With these models being highly…

Machine Learning · Computer Science 2025-06-06 Sanchit Sinha , Aidong Zhang

We introduce a new class of non-linear models for functional data based on neural networks. Deep learning has been very successful in non-linear modeling, but there has been little work done in the functional data setting. We propose two…

Machine Learning · Computer Science 2023-05-11 Aniruddha Rajendra Rao , Matthew Reimherr

Most state-of-the-art techniques for medical image segmentation rely on deep-learning models. These models, however, are often trained on narrowly-defined tasks in a supervised fashion, which requires expensive labeled datasets. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Heejong Kim , Victor Ion Butoi , Adrian V. Dalca , Daniel J. A. Margolis , Mert R. Sabuncu

Foundation models (FMs) such as large language models have revolutionized the field of AI by showing remarkable performance in various tasks. However, they exhibit numerous limitations that prevent their broader adoption in many real-world…

Artificial Intelligence · Computer Science 2024-02-05 Debarun Bhattacharjya , Junkyu Lee , Don Joven Agravante , Balaji Ganesan , Radu Marinescu

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

While foundation models have achieved remarkable results across a diversity of domains, they still rely on human-generated data, such as text, as a fundamental source of knowledge. However, this data is ultimately the product of human…

Neurons and Cognition · Quantitative Biology 2026-01-21 Maël Donoso

Deepfake or synthetic images produced using deep generative models pose serious risks to online platforms. This has triggered several research efforts to accurately detect deepfake images, achieving excellent performance on publicly…

Cryptography and Security · Computer Science 2024-04-26 Sifat Muhammad Abdullah , Aravind Cheruvu , Shravya Kanchi , Taejoong Chung , Peng Gao , Murtuza Jadliwala , Bimal Viswanath

Large AI models, or foundation models, are models recently emerging with massive scales both parameter-wise and data-wise, the magnitudes of which can reach beyond billions. Once pretrained, large AI models demonstrate impressive…

Artificial Intelligence · Computer Science 2023-09-26 Jianing Qiu , Lin Li , Jiankai Sun , Jiachuan Peng , Peilun Shi , Ruiyang Zhang , Yinzhao Dong , Kyle Lam , Frank P. -W. Lo , Bo Xiao , Wu Yuan , Ningli Wang , Dong Xu , Benny Lo

Many scientific fields, from medicine to seismology, rely on analyzing sequences of events over time to understand complex systems. Traditionally, machine learning models must be built and trained from scratch for each new dataset, which is…

Machine Learning · Computer Science 2026-01-21 David Berghaus , Patrick Seifner , Kostadin Cvejoski , Ramses J. Sanchez

Advances in machine learning over the past decade have resulted in a proliferation of algorithmic applications for encoding, characterizing, and acting on complex data that may contain many high dimensional features. Recently, the emergence…

Conceptual modeling is a strongly interdisciplinary field of research. Although numerous proposals for axiomatic foundations of the main ideas of the field exist, there is still a lack of understanding main concepts such as system, process,…

Software Engineering · Computer Science 2022-03-21 Peter Fettke , Wolfgang Reisig

Change detection, as an important and widely applied technique in the field of remote sensing, aims to analyze changes in surface areas over time and has broad applications in areas such as environmental monitoring, urban development, and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Zihan Yu , Tianxiao Li , Yuxin Zhu , Rongze Pan

This tutorial covers biomedical image reconstruction, from the foundational concepts of system modeling and direct reconstruction to modern sparsity and learning-based approaches. Imaging is a critical tool in biological research and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Michael T. McCann , Michael Unser