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Dynamical systems are frequently used to model biological systems. When these models are fit to data it is necessary to ascertain the uncertainty in the model fit. Here we present prediction deviation, a new metric of uncertainty that…

Applications · Statistics 2017-06-08 Benjamin Letham , Portia A. Letham , Cynthia Rudin , Edward P. Browne

A typical trajectory planner of autonomous driving commonly relies on predicting the future behavior of surrounding obstacles. Recently, deep learning technology has been widely adopted to design prediction models due to their impressive…

Artificial Intelligence · Computer Science 2022-07-29 Weitao Zhou , Zhong Cao , Yunkang Xu , Nanshan Deng , Xiaoyu Liu , Kun Jiang , Diange Yang

The optimal learner for prediction modeling varies depending on the underlying data-generating distribution. Super Learner (SL) is a generic ensemble learning algorithm that uses cross-validation to select among a "library" of candidate…

Many machine learning (ML) models are integrated within the context of a larger system as part of a key component for decision making processes. Concretely, predictive models are often employed in estimating the parameters for the input…

Machine Learning · Computer Science 2022-04-04 Bing Zhang , Yuya Jeremy Ong , Taiga Nakamura

After the diagnosis of a disease, one major objective is to predict cumulative probabilities of events such as clinical relapse or death from the individual information collected up to a prediction time, including usually biomarker repeated…

Applications · Statistics 2018-08-08 Loïc Ferrer , Hein Putter , Cécile Proust-Lima

Low-dimensional embeddings for data from disparate sources play critical roles in multi-modal machine learning, multimedia information retrieval, and bioinformatics. In this paper, we propose a supervised dimensionality reduction method…

Machine Learning · Computer Science 2021-01-15 Yanjun Li , Bihan Wen , Hao Cheng , Yoram Bresler

The rapid development of machine learning (ML) and artificial intelligence (AI) applications requires the training of large numbers of models. This growing demand highlights the importance of training models without human supervision, while…

Machine Learning · Computer Science 2025-05-26 Alexey Boldyrev , Fedor Ratnikov , Andrey Shevelev

Clinical research often focuses on complex traits in which many variables play a role in mechanisms driving, or curing, diseases. Clinical prediction is hard when data is high-dimensional, but additional information, like domain knowledge…

Methodology · Statistics 2020-05-21 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

Learned dynamics models combined with both planning and policy learning algorithms have shown promise in enabling artificial agents to learn to perform many diverse tasks with limited supervision. However, one of the fundamental challenges…

Machine Learning · Computer Science 2020-08-12 Suraj Nair , Silvio Savarese , Chelsea Finn

Joint models are well suited to modelling linked data from laboratories and health registers. However, there are few examples of joint models that allow for (a) multiple markers, (b) multiple survival outcomes (including terminal events,…

Just-In-Time (JIT) defect prediction aims to automatically predict whether a commit is defective or not, and has been widely studied in recent years. In general, most studies can be classified into two categories: 1) simple models using…

Software Engineering · Computer Science 2024-03-19 Xin Zhou , DongGyun Han , David Lo

The literature has proposed various robust alternatives to empirical risk minimisation to address failure modes such as distribution shift, label noise and finite-sample degeneracies. Examples include distributionally robust optimization,…

Machine Learning · Computer Science 2026-05-28 Jonas Hanselle , Valentin Margraf , Clemens Damke , Eyke Hüllermeier

Accurately predicting the consequences of agents' actions is a key prerequisite for planning in robotic control. Model-based reinforcement learning (MBRL) is one paradigm which relies on the iterative learning and prediction of state-action…

Machine Learning · Computer Science 2022-03-21 Nathan Lambert , Kristofer Pister , Roberto Calandra

The Super Learner (SL) is a widely used ensemble method that combines predictions from a library of learners based on their predictive performance. Interval predictions are of considerable practical interest because they allow uncertainty…

Machine Learning · Statistics 2026-04-27 Zhanli Wu , Fabrizio Leisen , Miguel-Angel Luque-Fernandez , F. Javier Rubio

Bolted joints are critical in engineering for maintaining structural integrity and reliability. Accurate prediction of parameters influencing their function and behavior is essential for optimal performance. Traditional methods often fail…

Machine Learning · Computer Science 2025-08-28 Ines Boujnah , Nehal Afifi , Andreas Wettstein , Sven Matthiesen

Ordinary differential equations (ODEs) provide a powerful framework for modeling dynamic systems arising in a wide range of scientific domains. However, most existing ODE methods focus on a single system, and do not adequately address the…

Methodology · Statistics 2026-04-08 Shuoxun Xu , Zijian Guo , Brooke R. Staveland , Robert T. Knight , Lexin Li

In the era of precision medicine, time-to-event outcomes such as time to death or progression are routinely collected, along with high-throughput covariates. These high-dimensional data defy classical survival regression models, which are…

Methodology · Statistics 2025-07-15 Stephen Salerno , Yi Li

Although with progress in introducing auxiliary amortized inference models, learning discrete latent variable models is still challenging. In this paper, we show that the annoying difficulty of obtaining reliable stochastic gradients for…

Machine Learning · Statistics 2020-05-29 Zhijian Ou , Yunfu Song

The problem of dynamic prediction with time-dependent covariates, given by biomarkers, repeatedly measured over time, has received much attention over the last decades. Two contrasting approaches have become in widespread use. The first is…

Methodology · Statistics 2021-03-31 Hein Putter , Hans C. van Houwelingen

Dynamic predictions of survival outcomes are of great interest to physicians and patients, since such predictions are useful elements of clinical decision-making. Joint modelling of longitudinal and survival data has been increasingly used…

Applications · Statistics 2019-06-10 Ozgur Asar , Marie-Cecile Fournier , Etienne Dantan