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The discovery of drug-target interactions (DTIs) plays a crucial role in pharmaceutical development. The deep learning model achieves more accurate results in DTI prediction due to its ability to extract robust and expressive features from…

Machine Learning · Computer Science 2024-04-17 Bin Liu , Siqi Wu , Jin Wang , Xin Deng , Ao Zhou

We propose a new learning method for heterogeneous domain adaptation (HDA), in which the data from the source domain and the target domain are represented by heterogeneous features with different dimensions. Using two different projection…

Machine Learning · Computer Science 2012-06-22 Lixin Duan , Dong Xu , Ivor Tsang

Advanced machine learning algorithms are increasingly utilized to provide data-based prediction and decision-making support in Industry 4.0. However, the prediction accuracy achieved by the existing models is insufficient to warrant…

Machine Learning · Computer Science 2024-03-06 Zhipeng Ma , Bo Nørregaard Jørgensen , Zheng Grace Ma

This paper focuses on developing a method to obtain an uncertain linear fractional transformation (LFT) system that adequately captures the dynamics of a nonlinear time-invariant system over some desired envelope. First, the nonlinear…

Systems and Control · Electrical Eng. & Systems 2023-05-02 Sourav Sinha , Devaprakash Muniraj , Mazen Farhood

Motivation: Identifying drug-target interactions (DTIs) is a key step in drug repositioning. In recent years, the accumulation of a large number of genomics and pharmacology data has formed mass drug and target related heterogeneous…

Machine Learning · Computer Science 2022-10-19 Hongzhun Wang , Feng Huang , Wen Zhang

In this study, we introduce an innovative methodology aimed at enhancing Fisher's Linear Discriminant Analysis (LDA) in the context of high-dimensional data classification scenarios, specifically addressing situations where each feature…

Applications · Statistics 2024-01-18 Seungyeon Oh , Hoyoung Park

Understanding the association between dietary patterns and health outcomes, such as the cancer risk, is crucial to inform public health guidelines and shaping future dietary interventions. However, dietary intake data present several…

Methodology · Statistics 2025-10-10 Blake Hansen , Dafne Zorzetto , Valeria Edefonti , Roberta De Vito

In this paper, we revisit the parameter learning problem, namely the estimation of model parameters for Dynamic Bayesian Networks (DBNs). DBNs are directed graphical models of stochastic processes that encompasses and generalize Hidden…

Machine Learning · Computer Science 2019-02-14 E. Benhamou , J. Atif , R. Laraki

Factor models are widely applied to the analysis of multivariate data across disparate fields of research. However, modern scientific data are often incomplete, and estimating a factor model from partially observed data can be very…

Methodology · Statistics 2026-02-24 Giuseppe Vinci

The black-box nature of large language models (LLMs) poses challenges in interpreting results, impacting issues such as data intellectual property protection and hallucination tracing. Training data attribution (TDA) methods are considered…

Computation and Language · Computer Science 2024-11-20 Kangxi Wu , Liang Pang , Huawei Shen , Xueqi Cheng

A linear multi-factor model is one of the most important tools in equity portfolio management. The linear multi-factor models are widely used because they can be easily interpreted. However, financial markets are not linear and their…

Machine Learning · Computer Science 2019-02-01 Kei Nakagawa , Tomoki Ito , Masaya Abe , Kiyoshi Izumi

Linear discriminant analysis (LDA) is a popular tool for classification and dimension reduction. Limited by its linear form and the underlying Gaussian assumption, however, LDA is not applicable in situations where the data distribution is…

Machine Learning · Computer Science 2020-11-02 Yunqi Cai , Dong Wang

Large Language Models (LLMs) such as Mistral and LLaMA have showcased remarkable performance across various natural language processing (NLP) tasks. Despite their success, these models inherit social biases from the diverse datasets on…

Computation and Language · Computer Science 2024-06-19 Nirmalendu Prakash , Lee Ka Wei Roy

Hyperspectral image (HSI) and LiDAR data joint classification is a challenging task. Existing multi-source remote sensing data classification methods often rely on human-designed frameworks for feature extraction, which heavily depend on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Junyan Lin , Feng Gap , Lin Qi , Junyu Dong , Qian Du , Xinbo Gao

Deep learning has proven to be a highly effective tool for a wide range of applications, significantly when leveraging the power of multi-loss functions to optimize performance on multiple criteria simultaneously. However, optimal selection…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Amin Golnari , Mostafa Diba

This work is concerned with robust filtering of nonlinear sampled-data systems with and without exact discrete-time models. A linear matrix inequality (LMI) based approach is proposed for the design of robust $H_{\infty}$ observers for a…

Systems and Control · Computer Science 2018-12-27 Masoud Abbaszadeh , Horacio J. Marquez

The increasing volume of drug combinations in modern therapeutic regimens needs reliable methods for predicting drug-drug interactions (DDIs). While Large Language Models (LLMs) have revolutionized various domains, their potential in…

Machine Learning · Computer Science 2025-02-12 Gabriele De Vito , Filomena Ferrucci , Athanasios Angelakis

For the purpose of effective suppression of the cycle-skipping phenomenon in full waveform inversion (FWI), we developed a Deep Neural Network (DNN) approach to predict the absent low-frequency components by exploiting the implicit relation…

Geophysics · Physics 2019-12-23 Wenyi Hu , Yuchen Jin , Xuqing Wu , Jiefu Chen

Recently proposed data-driven predictive control schemes for LTI systems use non-parametric representations based on the image of a Hankel matrix of previously collected, persistently exciting, input-output data. Persistence of excitation…

Systems and Control · Electrical Eng. & Systems 2024-03-07 Mohammad Alsalti , Manuel Barkey , Victor G. Lopez , Matthias A. Müller

Blind System Identification (BSI) is used to extract a system model whenever input data is not attainable. Therefore, the input data and system model should be estimated simultaneously. Because of nonlinearities in a large number of…

Systems and Control · Electrical Eng. & Systems 2024-05-17 Javad Zahedi Moghaddam , Hamidreza Momeni , Mojtaba Danesh