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Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge

Diabetic retinopathy (DR) is a prevalent complication of diabetes associated with a significant risk of vision loss. Timely identification is critical to curb vision impairment. Algorithms for DR staging from digital fundus images (DFIs)…

Image and Video Processing · Electrical Eng. & Systems 2023-12-25 Yevgeniy Men , Jonathan Fhima , Leo Anthony Celi , Lucas Zago Ribeiro , Luis Filipe Nakayama , Joachim A. Behar

A desirable property of any deployed artificial intelligence is generalization across domains, i.e. data generation distribution under a specific acquisition condition. In medical imagining applications the most coveted property for…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 Ayan Banerjee , Komandoor Srivathsan , Sandeep K. S. Gupta

Due to domain shift, deep neural networks (DNNs) usually fail to generalize well on unknown test data in practice. Domain generalization (DG) aims to overcome this issue by capturing domain-invariant representations from source domains.…

Machine Learning · Computer Science 2022-11-10 Feng Hou , Yao Zhang , Yang Liu , Jin Yuan , Cheng Zhong , Yang Zhang , Zhongchao Shi , Jianping Fan , Zhiqiang He

Diabetic Retinopathy (DR) is an art and science of recording and classifying the retinal images of a diabetic patient. DR classification deals with classifying retinal fundus image into five stages on the basis of severity of diabetes. One…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Nishi Doshi , Urvi Oza , Pankaj Kumar

The generalization of deep neural networks to unknown domains is a major challenge despite their tremendous progress in recent years. For this reason, the dynamic area of domain generalization (DG) has emerged. In contrast to unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Manuel Schwonberg , Hanno Gottschalk

Clinical magnetic-resonance (MR) protocols generate many T1 and T2 sequences whose appearance differs more than the acquisition sites that produce them. Existing domain-generalization benchmarks focus almost on cross-center shifts and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Zheyuan Zhang , Linkai Peng , Wanying Dou , Cuiling Sun , Halil Ertugrul Aktas , Andrea M. Bejar , Elif Keles , Gorkem Durak , Ulas Bagci

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

Data-driven machine learning (ML) is promoted as one potential technology to be used in next-generations wireless systems. This led to a large body of research work that applies ML techniques to solve problems in different layers of the…

Machine Learning · Computer Science 2023-03-15 Mohamed Akrout , Amal Feriani , Faouzi Bellili , Amine Mezghani , Ekram Hossain

The distribution shifts between training and test data typically undermine the performance of models. In recent years, lots of work pays attention to domain generalization (DG) where distribution shifts exist, and target data are unseen.…

Machine Learning · Computer Science 2024-01-05 Wang Lu , Jindong Wang , Yidong Wang , Xing Xie

Most statistical learning algorithms rely on an over-simplified assumption, that is, the train and test data are independent and identically distributed. In real-world scenarios, however, it is common for models to encounter data from new…

Image and Video Processing · Electrical Eng. & Systems 2023-04-07 Zheyuan Zhang , Bin Wang , Lanhong Yao , Ugur Demir , Debesh Jha , Ismail Baris Turkbey , Boqing Gong , Ulas Bagci

Single-source domain generalization (SDG) aims to learn a model from a single source domain that can generalize well on unseen target domains. This is an important task in computer vision, particularly relevant to medical imaging where…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Boqi Chen , Yuanzhi Zhu , Yunke Ao , Sebastiano Caprara , Reto Sutter , Gunnar Rätsch , Ender Konukoglu , Anna Susmelj

Diabetic Retinopathy (DR) is a leading cause of vision loss in the world, and early DR detection is necessary to prevent vision loss and support an appropriate treatment. In this work, we leverage interactive machine learning and introduce…

While deep neural networks demonstrate state-of-the-art performance on a variety of learning tasks, their performance relies on the assumption that train and test distributions are the same, which may not hold in real-world applications.…

Machine Learning · Computer Science 2021-02-18 Wenyu Zhang , Mohamed Ragab , Ramon Sagarna

In this paper, we propose two distinct solutions to the problem of Diabetic Retinopathy (DR) classification. In the first approach, we introduce a shallow neural network architecture. This model performs well on classification of the most…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Hangwei Zhuang , Nabil Ettehadi

Deep neural networks often suffer performance drops when test data distribution differs from training data. Domain Generalization (DG) aims to address this by focusing on domain-invariant features or augmenting data for greater diversity.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Nam Duong Tran , Nam Nguyen Phuong , Hieu H. Pham , Phi Le Nguyen , My T. Thai

The significant portion of diabetic patients was affected due to major blindness caused by Diabetic retinopathy (DR). For diabetic retinopathy, lesion segmentation, and detection the comprehensive examination is delved into the deep…

Artificial Intelligence · Computer Science 2024-11-20 Syed Mohd Faisal Malik , Md Tabrez Nafis , Mohd Abdul Ahad , Safdar Tanweer

Domain generalization (DG) serves as a promising solution to handle person Re-Identification (Re-ID), which trains the model using labels from the source domain alone, and then directly adopts the trained model to the target domain without…

Information Retrieval · Computer Science 2020-07-28 Peixian Chen , Pingyang Dai , Jianzhuang Liu , Feng Zheng , Qi Tian , Rongrong Ji

Deep learning has achieved remarkable success in medical image classification. However, its clinical application is often hindered by data heterogeneity caused by variations in scanner vendors, imaging protocols, and operators. Approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Yaoyao Zhu , Xiuding Cai , Yingkai Wang , Yu Yao , Xu Luo , Zhongliang Fu

Diabetic retinopathy (DR), a serious ocular complication of diabetes, is one of the primary causes of vision loss among retinal vascular diseases. Deep learning methods have been extensively applied in the grading of diabetic retinopathy…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Yunxuan Wang , Ray Yin , Yumei Tan , Hao Chen , Haiying Xia