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Modeling and drawing inference on the joint associations between single nucleotide polymorphisms and a disease has sparked interest in genome-wide associations studies. In the motivating Boston Lung Cancer Survival Cohort (BLCSC) data, the…

Methodology · Statistics 2021-11-18 Lu Xia , Bin Nan , Yi Li

We investigate the problem of reconstructing signals from a subsampled convolution of their modulated versions and a known filter. The problem is studied as applies to specific imaging systems relying on spatial phase modulation by randomly…

Information Theory · Computer Science 2016-03-23 Sohail Bahmani , Justin Romberg

Covariate adjustment is widely recommended to improve statistical efficiency in randomized clinical trials (RCTs), yet empirical evidence comparing available strategies remains limited. This lack of real-world evaluation leaves unresolved…

Applications · Statistics 2026-02-03 Yulin Shao , Liangbo Lyu , Menggang Yu , Bingkai Wang

One of the hallmarks of active galactic nuclei are that they are highly variable with time. In watching the spectra vary it has been observed that the emission-lines often appear to "reverberate" -- that is they vary in response to…

Astrophysics of Galaxies · Physics 2026-05-28 Kirk Long , Keith Horne , Jason Dexter , Benoit Tremblay

A fruitful approach for solving signal deconvolution problems consists of resorting to a frame-based convex variational formulation. In this context, parallel proximal algorithms and related alternating direction methods of multipliers have…

Other Computer Science · Computer Science 2015-05-28 Nelly Pustelnik , Jean-Christophe Pesquet , Caroline Chaux

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

A new maximum likelihood method for deconvoluting a continuous density with a positive lower bound on a known compact support in additive measurement error models with known error distribution using the approximate Bernstein type polynomial…

Methodology · Statistics 2018-01-30 Zhong Guan

Photomultiplier tubes (PMTs) are extensively employed as photosensors in neutrino and dark matter detection. The precise charge and timing information extracted from the PMT waveform plays a crucial role in energy and vertex reconstruction.…

Instrumentation and Detectors · Physics 2025-02-14 Jingzhe Tang , Tianying Xiao , Xuan Tang , Yongbo Huang

In this paper we consider a statistical estimation problem known as atomic deconvolution. Introduced in reliability, this model has a direct application when considering biological data produced by flow cytometers. In these experiments,…

Statistics Theory · Mathematics 2017-10-12 Manon Costa , Sébastien Gadat , Pauline Gonnord , Laurent Risser

Bulk tissue RNA sequencing of heterogeneous samples provides averaged gene expression profiles, obscuring cell type-specific dynamics. To address this, we present a probabilistic hierarchical Bayesian model that deconvolves bulk RNA-seq…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Mingyuan Shao , Daniel Bauer

Linear classifiers with random convolution kernels are computationally efficient methods that need no design or domain knowledge. Unlike deep neural networks, there is no need to hand-craft a network architecture; the kernels are randomly…

Signal Processing · Electrical Eng. & Systems 2021-08-05 Christopher Lundy , John M. O'Toole

Consider a network of $N$ decentralized computing agents collaboratively solving a nonconvex stochastic composite problem. In this work, we propose a single-loop algorithm, called DEEPSTORM, that achieves optimal sample complexity for this…

Optimization and Control · Mathematics 2023-04-14 Gabriel Mancino-Ball , Shengnan Miao , Yangyang Xu , Jie Chen

Dense retrieval models use bi-encoder network architectures for learning query and document representations. These representations are often in the form of a vector representation and their similarities are often computed using the dot…

Information Retrieval · Computer Science 2023-05-01 Hamed Zamani , Michael Bendersky

Previous multi-task dense prediction methods based on the Mixture of Experts (MoE) have received great performance but they neglect the importance of explicitly modeling the global relations among all tasks. In this paper, we present a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yuqi Yang , Peng-Tao Jiang , Qibin Hou , Hao Zhang , Jinwei Chen , Bo Li

We propose a novel method that performs adaptive clustering with DPMM using collapsed VI, while incorporating weakly-informative priors for DP concentration parameter alpha and base distribution G0. We illustrate the importance of G0…

Methodology · Statistics 2026-02-19 Annesh Pal , Aguirre Mimoun , Rodolphe Thiébaut , Boris P. Hejblum

Estimation of the mean vector and covariance matrix is of central importance in the analysis of multivariate data. In the framework of generalized linear models, usually the variances are certain functions of the means with the normal…

Methodology · Statistics 2023-01-25 Anupam Kundu , Mohsen Pourahmadi

We consider the problem of making nonparametric inference in a class of multi-dimensional diffusions in divergence form, from low-frequency data. Statistical analysis in this setting is notoriously challenging due to the intractability of…

Methodology · Statistics 2025-01-23 Matteo Giordano , Sven Wang

Accurate diagnostic tests are essential for effective screening and treatment. However, individual biomarkers often fail to provide sufficient diagnostic accuracy, as they typically capture only one aspect of the complex disease process.…

Methodology · Statistics 2025-07-08 Ainesh Sewak , Sandra Siegfried , Torsten Hothorn

Studies often estimate associations between an outcome and multiple variates. For example, studies of diagnostic test accuracy estimate sensitivity and specificity, and studies of predictive and prognostic factors typically estimate…

The emergence of deep learning techniques has advanced the image segmentation task, especially for medical images. Many neural network models have been introduced in the last decade bringing the automated segmentation accuracy close to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Ngoc-Du Tran , Thi-Thao Tran , Quang-Huy Nguyen , Manh-Hung Vu , Van-Truong Pham