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Microvascular anatomy is known to be involved in various neurological disorders. However, understanding these disorders is hindered by the lack of imaging modalities capable of capturing the comprehensive three-dimensional vascular network…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Etienne Chollet , Yaël Balbastre , Chiara Mauri , Caroline Magnain , Bruce Fischl , Hui Wang

Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or…

Optical Coherence Tomography (OCT) is a widely used non-invasive imaging technique that provides detailed three-dimensional views of the retina, which are essential for the early and accurate diagnosis of ocular diseases. Consequently, OCT…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Huy Minh Nhat Nguyen , Triet Hoang Minh Dao , Chau Vinh Hoang Truong , Cuong Tuan Nguyen

Optical coherence tomography (OCT) as retina imaging technology is currently used by ophthalmologist as a non-invasive and non-contact method for diagnosis of agerelated degeneration (AMD) and diabetic macular edema (DME) diseases. Fluid…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Elyas Rashno , Abdolreza Rashno , Sadegh Fadaei

Retinal vessel information is helpful in retinal disease screening and diagnosis. Retinal vessel segmentation provides useful information about vessels and can be used by physicians during intraocular surgery and retinal diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2018-02-23 M. Hajabdollahi , R. Esfandiarpoor , S. M. R. Soroushmehr , N. Karimi , S. Samavi , K. Najarian

Optical Coherence Tomography allows ophthalmologist to obtain cross-section imaging of eye retina. Assisted with digital image analysis methods, effective disease detection could be performed. Various methods exist to extract feature from…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Kuntoro Adi Nugroho

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

Optical Coherence Tomography (OCT) provides high-resolution cross-sectional images useful for diagnosing various diseases, but their distinct characteristics from natural images raise questions about whether large-scale pre-training on…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Zihao Han , Philippe De Wilde

Serial sectioning Optical Coherence Tomography (sOCT) is a high-throughput, label free microscopic imaging technique that is becoming increasingly popular to study post-mortem neurovasculature. Quantitative analysis of the vasculature…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Etienne Chollet , Yael Balbastre , Caroline Magnain , Bruce Fischl , Hui Wang

Estimation of blood oxygenation with spectroscopic photoacoustic imaging is a promising tool for several biomedical applications. For this method to be quantitative, it relies on an accurate method of the light fluence in the tissue. This…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Geoffrey P. Luke , Kevin Hoffer-Hawlik , Austin C. Van Namen , Ruibo Shang

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Shuang Zeng , Chee Hong Lee , Kaiwen Li , Boxu Xie , Ourui Fu , Hangzhou He , Lei Zhu , Yanye Lu , Fangxiao Cheng

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Jun Wang , Yang Zhao , Linglong Qian , Xiaohan Yu , Yongsheng Gao

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Roshan Kenia , Anfei Li , Rishabh Srivastava , Kaveri A. Thakoor

To develop a new method to quantify nonperfused retinal capillaries (NPCs) by using co-registered optical coherence tomography (OCT) and OCT angiography (OCTA), and to evaluate NPCs in eyes with age-related macular degeneration (AMD) and…

Quantitative Methods · Quantitative Biology 2024-11-11 Min Gao , Yukun Guo , Tristan T. Hormel , Jie Wang , Elizabeth White , Dong-Wouk Park , Thomas S. Hwang , Steven T. Bailey , Yali Jia

Human veins are important for carrying the blood from the body-parts to the heart. The improper functioning of the human veins may arise from several venous diseases. Varicose vein is one such disease wherein back flow of blood can occur,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Maryam Viqar , Violeta Madjarova , Vipul Baghel , Elena Stoykova

Coronary artery segmentation on coronary-computed tomography angiography (CCTA) images is crucial for clinical use. Due to the expertise-required and labor-intensive annotation process, there is a growing demand for the relevant…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Zheng Zhang , Xiaolei Zhang , Yaolei Qi , Guanyu Yang

The U-Net architecture and its variants have remained state-of-the-art (SOTA) for retinal vessel segmentation over the past decade. In this study, we introduce a Full-Scale Guided Network (FSG-Net), where a novel feature representation…

Image and Video Processing · Electrical Eng. & Systems 2025-12-25 Sunyong Seo , Sangwook Yoo , Huisu Yoon

Retinal vessel segmentation is critical for the early diagnosis of vision-threatening and systemic diseases, especially in real-world clinical settings with limited computational resources. Although significant improvements have been made…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Mehwish Mehmood , Shahzaib Iqbal , Tariq Mahmood Khan , Ivor Spence , Muhammad Fahim