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Fundus photography (FP) remains the primary imaging modality in screening various retinal diseases including age-related macular degeneration, diabetic retinopathy and glaucoma. FP allows the clinician to examine the ocular fundus…

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Medical image segmentation is crucial for diagnosis and treatment planning. Traditional CNN-based models, like U-Net, have shown promising results but struggle to capture long-range dependencies and global context. To address these…

Observing retinal fundus images by an ophthalmologist is a major diagnosis approach for glaucoma. However, it is still difficult to distinguish the features of the lesion solely through manual observations, especially, in glaucoma early…

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Despite the remarkable success of the end-to-end paradigm in deep learning, it often suffers from slow convergence and heavy reliance on large-scale datasets, which fundamentally limits its efficiency and applicability in data-scarce…

The prevalence of diabetic retinopathy (DR) has reached 34.6% worldwide and is a major cause of blindness among middle-aged diabetic patients. Regular DR screening using fundus photography helps detect its complications and prevent its…

Electron microscopy (EM) imaging offers unparalleled resolution for analyzing neural tissues, crucial for uncovering the intricacies of synaptic connections and neural processes fundamental to understanding behavioral mechanisms. Recently,…

Medical image processing tasks such as segmentation often require capturing non-local information. As organs, bones, and tissues share common characteristics such as intensity, shape, and texture, the contextual information plays a critical…

Universal lesion detection (ULD) on computed tomography (CT) images is an important but underdeveloped problem. Recently, deep learning-based approaches have been proposed for ULD, aiming to learn representative features from annotated CT…

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Salient object detection has achieved great improvement by using the Fully Convolution Network (FCN). However, the FCN-based U-shape architecture may cause the dilution problem in the high-level semantic information during the up-sample…

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

We propose a robust alignment technique for Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which are challenging to align due to differences in scale, appearance, and the scarcity of distinctive features. Our…

Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective…

Parameter-Efficient Fine-Tuning (PEFT) has become a dominant paradigm for deploying LLMs in multi-task scenarios due to its extreme parameter efficiency. While Mixture-of-Experts (MoE) based LoRA variants have achieved promising results by…

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

Childhood myopia constitutes a significant global health concern. It exhibits an escalating prevalence and has the potential to evolve into severe, irreversible conditions that detrimentally impact familial well-being and create substantial…

Defocus blur is a persistent problem in microscope imaging that poses harm to pathology interpretation and medical intervention in cell microscopy and microscope surgery. To address this problem, a unified framework including the…