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Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

Background and Objectives: Multidrug Resistance (MDR) is a critical global health issue, causing increased hospital stays, healthcare costs, and mortality. This study proposes an interpretable Machine Learning (ML) framework for MDR…

The primary aim of this paper is to comprehend, assess, and analyze the role, relevance, and efficiency of machine learning models in predicting heart disease risks using clinical data. While the importance of heart disease risk prediction…

Machine Learning · Computer Science 2024-10-22 Balaji Shesharao Ingole , Vishnu Ramineni , Nikhil Bangad , Koushik Kumar Ganeeb , Priyankkumar Patel

Although electrocardiograms (ECG) play a dominant role in cardiovascular diagnosis and treatment, their intrinsic data forms and representational patterns pose significant challenges for medical multimodal large language models (Med-MLLMs)…

Continuous photoplethysmography (PPG)-based blood pressure monitoring is necessary for healthcare and fitness applications. In Artificial Intelligence (AI), signal classification levels with the machine and deep learning arrangements need…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Nida Nasir , Mustafa Sameer , Feras Barneih , Omar Alshaltone , Muneeb Ahmed

The objective of this work is to develop an Electronic Medical Record (EMR) data processing tool that confers clinical context to Machine Learning (ML) algorithms for error handling, bias mitigation and interpretability. We present…

Uncertainty Quantification (UQ) is pivotal in enhancing the robustness, reliability, and interpretability of Machine Learning (ML) systems for healthcare, optimizing resources and improving patient care. Despite the emergence of ML-based…

Machine Learning · Computer Science 2025-05-07 L. Julián Lechuga López , Shaza Elsharief , Dhiyaa Al Jorf , Firas Darwish , Congbo Ma , Farah E. Shamout

Despite advancements in medical care, hip fractures impose a significant burden on individuals and healthcare systems. This paper focuses on the prediction of hip fracture risk in older and middle-aged adults, where falls and compromised…

Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of…

Machine Learning · Computer Science 2021-03-23 Shuyu Lu , Ruoyu Chen , Wei Wei , Xinghua Lu

Prognostic information is essential for decision-making in breast cancer management. Recently trials have predominantly focused on genomic prognostication tools, even though clinicopathological prognostication is less costly and more widely…

The availability of large and deep electronic healthcare records (EHR) datasets has the potential to enable a better understanding of real-world patient journeys, and to identify novel subgroups of patients. ML-based aggregation of EHR data…

Machine Learning · Computer Science 2022-08-03 Owen Parsons , Nathan E Barlow , Janie Baxter , Karen Paraschin , Andrea Derix , Peter Hein , Robert Dürichen

Single-photon emission computed tomography (SPECT) provides a mechanism to estimate regional isotope uptake in lesions and at-risk organs after administration of {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs).…

Cluster-randomized trials (CRTs) are widely used to evaluate interventions delivered at the clinic, practice, or community level. Although standard analyses typically target average treatment effects, such summaries mask potentially…

Methodology · Statistics 2026-04-16 Changjun Li , Xi Fang , Michael O. Harhay , Andrew B. Forbes , F. Perry Wilson , Guangyu Tong , Fan Li

Deep learning has improved automated electrocardiogram (ECG) classification, but limited insight into prediction reliability hinders its use in safety-critical settings. This paper proposes UCTECG-Net, an uncertainty-aware hybrid…

Machine Learning · Computer Science 2026-02-19 Hamzeh Asgharnezhad , Pegah Tabarisaadi , Abbas Khosravi , Roohallah Alizadehsani , U. Rajendra Acharya

Echocardiography (echo) is an ultrasound imaging modality that is widely used for various cardiovascular diagnosis tasks. Due to inter-observer variability in echo-based diagnosis, which arises from the variability in echo image acquisition…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Masoud Mokhtari , Neda Ahmadi , Teresa S. M. Tsang , Purang Abolmaesumi , Renjie Liao

Practical machine learning systems often operate in multiple sequential stages, as seen in ranking and recommendation systems, which typically include a retrieval phase followed by a ranking phase. Effectively assessing prediction…

Information Retrieval · Computer Science 2025-02-04 Yunpeng Xu , Mufang Ying , Wenge Guo , Zhi Wei

While many machine learning methods have been used for medical prediction and risk factor analysis on healthcare data, most prior research has involved single-task learning (STL) methods. However, healthcare research often involves multiple…

Machine Learning · Computer Science 2021-03-08 Lu Wang , Haoyan Jiang , Mark Chignell

Cardiac disease evaluation depends on multiple diagnostic modalities: electrocardiogram (ECG) to diagnose abnormal heart rhythms, and imaging modalities such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and echocardiography…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Evariste Njomgue Fotso , Buntheng Ly , Hubert Cochet , Maxime Sermesant

Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Omini Rathore , Richard Paul , Abigail Morrison , Hanno Scharr , Elisabeth Pfaehler

Biopharmaceutical products, particularly monoclonal antibodies (mAbs), have gained prominence in the pharmaceutical market due to their high specificity and efficacy. As these products are projected to constitute a substantial portion of…

Quantitative Methods · Quantitative Biology 2024-09-05 Thanh Tung Khuat , Robert Bassett , Ellen Otte , Bogdan Gabrys