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Digital pathology involves converting physical tissue slides into high-resolution Whole Slide Images (WSIs), which pathologists analyze for disease-affected tissues. However, large histology slides with numerous microscopic fields pose…

Image and Video Processing · Electrical Eng. & Systems 2024-02-19 Mobina Mansoori , Sajjad Shahabodini , Jamshid Abouei , Arash Mohammadi , Konstantinos N. Plataniotis

Whole slide image (WSI) classification is an essential task in computational pathology. Despite the recent advances in multiple instance learning (MIL) for WSI classification, accurate classification of WSIs remains challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Saisai Ding , Jun Wang , Juncheng Li , Jun Shi

Learning suitable Whole slide images (WSIs) representations for efficient retrieval systems is a non-trivial task. The WSI embeddings obtained from current methods are in Euclidean space not ideal for efficient WSI retrieval. Furthermore,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-26 Sobhan Hemati , Shivam Kalra , Morteza Babaie , H. R. Tizhoosh

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Deep convolutional neural networks(CNNs) have been successful for a wide range of computer vision tasks, including image classification. A specific area of the application lies in digital pathology for pattern recognition in the…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Rasoul Sali , Sodiq Adewole , Lubaina Ehsan , Lee A. Denson , Paul Kelly , Beatrice C. Amadi , Lori Holtz , Syed Asad Ali , Sean R. Moore , Sana Syed , Donald E. Brown

Whole slide images (WSIs) are the gold standard for pathological diagnosis and sub-typing. Current main-stream two-step frameworks employ offline feature encoders trained without domain-specific knowledge. Among them, attention-based…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Mingrui Ma , Chentao Li , Pan Huang , Jing Qin

Graph Transformer (GT) has recently emerged as a promising neural network architecture for learning graph-structured data. However, its global attention mechanism with quadratic complexity concerning the graph scale prevents wider…

Machine Learning · Computer Science 2024-12-09 Ningyi Liao , Zihao Yu , Siqiang Luo

Whole Slide Images (WSIs) provide exceptional detail for studying tissue architecture at the cell level. To study tumour microenvironment (TME) with the context of various protein biomarkers and cell sub-types, analysis and registration of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Adith Jeyasangar , Abdullah Alsalemi , Shan E Ahmed Raza

Transformers have revolutionized performance in Natural Language Processing and Vision, paving the way for their integration with Graph Neural Networks (GNNs). One key challenge in enhancing graph transformers is strengthening the…

Machine Learning · Computer Science 2026-01-09 Yun Young Choi , Sun Woo Park , Minho Lee , Youngho Woo

Recent AI navigation approaches aim to improve Whole-Slide Image (WSI) diagnosis by modeling spatial exploration and selecting diagnostically relevant regions, yet most operate at a single fixed magnification or rely on predefined…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zhengyang Xu , Han Li , Jingsong Liu , Linrui Xie , Xun Ma , Xin You , Shihui Zu , Ayako Ito , Xinyu Hao , Hongming Xu , Shaohua Kevin Zhou , Nassir Navab , Peter J. Schüffler

Whole slide images (WSIs) are vital in digital pathology, enabling gigapixel tissue analysis across various pathological tasks. While recent advancements in multi-modal large language models (MLLMs) allow multi-task WSI analysis through…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Xinheng Lyu , Yuci Liang , Wenting Chen , Meidan Ding , Jiaqi Yang , Guolin Huang , Daokun Zhang , Xiangjian He , Linlin Shen

Group Re-identification (G-ReID) faces greater complexity than individual Re-identification (ReID) due to challenges like mutual occlusion, dynamic member interactions, and evolving group structures. Prior graph-based approaches have aimed…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Ruiqi Liu , Xingyu Liu , Xiaohao Xu , Yixuan Zhang , Yongxin Ge , Lubin Weng

Whole Slide Images (WSIs) or histopathology images are used in digital pathology. WSIs pose great challenges to deep learning models for clinical diagnosis, owing to their size and lack of pixel-level annotations. With the recent…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Soham Rohit Chitnis , Sidong Liu , Tirtharaj Dash , Tanmay Tulsidas Verlekar , Antonio Di Ieva , Shlomo Berkovsky , Lovekesh Vig , Ashwin Srinivasan

Transformer-based architectures start to emerge in single image super resolution (SISR) and have achieved promising performance. Most existing Vision Transformers divide images into the same number of patches with a fixed size, which may…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Qing Cai , Yiming Qian , Jinxing Li , Jun Lv , Yee-Hong Yang , Feng Wu , David Zhang

Most existing methods for predicting drug-drug interactions (DDI) predominantly concentrate on capturing the explicit relationships among drugs, overlooking the valuable implicit correlations present between drug pairs (DPs), which leads to…

Machine Learning · Computer Science 2024-02-29 Mengying Jiang , Guizhong Liu , Yuanchao Su , Weiqiang Jin , Biao Zhao

Consecutive thin sections of tissue samples make it possible to study local variation in e.g. protein expression and tumor heterogeneity by staining for a new protein in each section. In order to compare and correlate patterns of different…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Leslie Solorzano , Gabriela M. Almeida , Bárbara Mesquita , Diana Martins , Carla Oliveira , Carolina Wählby

Deciphering tumor microenvironment from Whole Slide Images (WSIs) is intriguing as it is key to cancer diagnosis, prognosis and treatment response. While these gigapixel images on one hand offer a comprehensive portrait of cancer, on the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Kunpeng Zhang , Hanwen Xu , Sheng Wang

Pathologists routinely alternate between different magnifications when examining Whole-Slide Images, allowing them to evaluate both broad tissue morphology and intricate cellular details to form comprehensive diagnoses. However, existing…

Recent advancements in digital pathology have enabled comprehensive analysis of Whole-Slide Images (WSI) from tissue samples, leveraging high-resolution microscopy and computational capabilities. Despite this progress, there is a lack of…

Image manipulation detection is to identify the authenticity of each pixel in images. One typical approach to uncover manipulation traces is to model image correlations. The previous methods commonly adopt the grids, which are fixed-size…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Xudong Wang , Jiaran Zhou , Huiyu Zhou , Junyu Dong , Yuezun Li