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Polymerase chain reaction (PCR) testing is the gold standard for diagnosing COVID-19. PCR amplifies the virus DNA 40 times to produce measurements of viral loads that span seven orders of magnitude. Unfortunately, the outputs of these tests…

Quantitative Methods · Quantitative Biology 2022-01-19 Hsin-Po Wang , Ryan Gabrys , Alexander Vardy

Recent advances in noiseless non-adaptive group testing have led to a precise asymptotic characterization of the number of tests required for high-probability recovery in the sublinear regime $k = n^{\theta}$ (with $\theta \in (0,1)$), with…

Data Structures and Algorithms · Computer Science 2021-12-24 Oliver Gebhard , Max Hahn-Klimroth , Olaf Parczyk , Manuel Penschuck , Maurice Rolvien , Jonathan Scarlett , Nelvin Tan

We consider the problem of non-adaptive noiseless group testing of $N$ items of which $K$ are defective. We describe four detection algorithms: the COMP algorithm of Chan et al.; two new algorithms, DD and SCOMP, which require stronger…

Information Theory · Computer Science 2014-05-20 Matthew Aldridge , Leonardo Baldassini , Oliver Johnson

Group testing enables to identify infected individuals in a population using a smaller number of tests than individual testing. To achieve this, group testing algorithms commonly assume knowledge of the number of infected individuals;…

Information Theory · Computer Science 2023-05-16 Chaorui Yao , Pavlos Nikolopoulos , Christina Fragouli

In this paper, we introduce a variation of the group testing problem capturing the idea that a positive test requires a combination of multiple ``types'' of item. Specifically, we assume that there are multiple disjoint \emph{semi-defective…

Information Theory · Computer Science 2024-05-10 Thach V. Bui , Jonathan Scarlett

PCR testing is an invaluable diagnostic tool that has most recently seen widespread use during the COVID-19 pandemic. A recent work by Wang, Gabrys and Vardy proposed tropical codes as a model for group PCR testing. For a known but…

Information Theory · Computer Science 2023-05-10 Nicholas Kwan , Lele Wang

Group testing is a well known search problem that consists in detecting the defective members of a set of objects O by performing tests on properly chosen subsets (pools) of the given set O. In classical group testing the goal is to find…

Data Structures and Algorithms · Computer Science 2016-06-13 Annalisa De Bonis

We study the group testing problem with non-adaptive randomized algorithms. Several models have been discussed in the literature to determine how to randomly choose the tests. For a model ${\cal M}$, let $m_{\cal M}(n,d)$ be the minimum…

Machine Learning · Computer Science 2019-11-06 Nader H. Bshouty , George Haddad , Catherine A. Haddad-Zaknoon

The original problem of group testing consists in the identification of defective items in a collection, by applying tests on groups of items that detect the presence of at least one defective item in the group. The aim is then to identify…

Applications · Statistics 2021-06-10 Emilien Joly , Bastien Mallein

We consider the nonadaptive group testing with N items, of which $K = \Theta(N^\theta)$ are defective. We study a test design in which each item appears in nearly the same number of tests. For each item, we independently pick L tests…

Information Theory · Computer Science 2018-09-26 Oliver Johnson , Matthew Aldridge , Jonathan Scarlett

In group testing, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether any defective item is present. This problem is relevant in areas such as medical testing, data…

Information Theory · Computer Science 2020-11-11 Nelvin Tan , Jonathan Scarlett

We consider a generalization of group testing where the potentially contaminated sets are the members of a given hypergraph ${\cal F}=(V,E)$. This generalization finds application in contexts where contaminations can be conditioned by some…

Data Structures and Algorithms · Computer Science 2023-11-28 Annalisa De Bonis

In the classical non-adaptive group testing setup, pools of items are tested together, and the main goal of a recovery algorithm is to identify the "complete defective set" given the outcomes of different group tests. In contrast, the main…

Information Theory · Computer Science 2016-03-01 Abhay Sharma , Chandra R. Murthy

We study the problem usually referred to as group testing in the context of COVID-19. Given n samples collected from patients, how should we select and test mixtures of samples to maximize information and minimize the number of tests? Group…

Machine Learning · Computer Science 2020-08-07 Louis Abraham , Gary Becigneul , Benjamin Coleman , Bernhard Scholkopf , Anshumali Shrivastava , Alexander Smola

Tropical differential equations are introduced and an algorithm is designed which tests solvability of a system of tropical linear differential equations within the complexity polynomial in the size of the system and in its coefficients.…

Symbolic Computation · Computer Science 2018-11-08 Dima Grigoriev

In this paper, we consider the problem of noiseless non-adaptive probabilistic group testing, in which the goal is high-probability recovery of the defective set. We show that in the case of $n$ items among which $k$ are defective, the…

Information Theory · Computer Science 2021-07-30 Wei Heng Bay , Eric Price , Jonathan Scarlett

We prove the first, even super-polynomial, lower bounds on the size of tropical (min,+) and (max,+) circuits approximating given optimization problems. Many classical dynamic programming (DP) algorithms for optimization problems are pure in…

Computational Complexity · Computer Science 2020-12-24 Stasys Jukna , Hannes Seiwert

Among the challenges that the COVID-19 pandemic outbreak revealed is the problem to reduce the number of tests required for identifying the virus carriers in order to contain the viral spread while preserving the tests reliability. To cope…

Information Theory · Computer Science 2021-12-24 Catherine A. Haddad-Zaaknoon

We study the problem usually referred to as group testing in the context of COVID-19. Given $n$ samples taken from patients, how should we select mixtures of samples to be tested, so as to maximize information and minimize the number of…

Methodology · Statistics 2020-05-14 Louis Abraham , Gary Bécigneul , Bernhard Schölkopf

We consider Bernoulli nonadaptive group testing with $k = \Theta(n^\theta)$ defectives, for $\theta \in (0,1)$. The practical definite defectives (DD) detection algorithm is known to be optimal for $\theta \geq 1/2$. We give a new upper…

Information Theory · Computer Science 2017-11-27 Matthew Aldridge
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