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Compartmental epidemiological models categorize individuals based on their disease status, such as the SEIRD model (Susceptible-Exposed-Infected-Recovered-Dead). These models determine the parameters that influence the magnitude of an…

Artificial Intelligence · Computer Science 2023-08-01 Alejandro Rodríguez-Arias , Amparo Alonso-Betanzos , Bertha Guijarro-Berdiñas , Noelia Sánchez-Marroño

Multiple lines of evidence strongly suggest that infection hotspots, where a single individual infects many others, play a key role in the transmission dynamics of COVID-19. However, most of the existing epidemiological models fail to…

Forecasts of hospitalisations of infectious diseases play an important role for allocating healthcare resources during epidemics and pandemics. Large-scale analysis of model forecasts during the COVID-19 pandemic has shown that the model…

Populations and Evolution · Quantitative Biology 2025-05-20 Grégoire Béchade , Torbjörn Lundh , Philip Gerlee

The COVID-19 pandemic has presented unprecedented challenges worldwide, necessitating effective modelling approaches to understand and control its transmission dynamics. In this study, we propose a novel approach that integrates…

Populations and Evolution · Quantitative Biology 2025-01-14 Moein Khalighi , Leo Lahti , Faïçal Ndaïrou , Peter Rashkov , Delfim F. M. Torres

The main focus of this chapter is on public health control strategies which are currently the main way to mitigate COVID-19 pandemic. We introduce and compare compartmental models of increasing complexity for COVID-19 transmission to…

Populations and Evolution · Quantitative Biology 2020-12-14 Redouane Qesmi , Aayah Hammoumi

A generalisation of the Susceptible-Infectious model is made to include a time-dependent transmission rate, which leads to a close analytical expression in terms of a logistic function. The solution can be applied to any continuous function…

Physics and Society · Physics 2020-10-08 L. Arturo Urena-Lopez , Alma X. Gonzalez-Morales

Since the beginning of the epidemic, daily reports of CoViD-19 cases, hospitalizations, and deaths from around the world have been publicly available. This paper describes methods to characterize broad features of the spread of the disease,…

Physics and Society · Physics 2020-07-15 Dean Karlen

Pandemic control measures like lock-down, restrictions on restaurants and gatherings, social-distancing have shown to be effective in curtailing the spread of COVID-19. However, their sustained enforcement has negative economic effects. To…

In Fall 2020, several European countries reported rapid increases in COVID-19 cases along with growing estimates of the effective reproduction rates. Such an acceleration in epidemic spread is usually attributed to time-dependent effects,…

Populations and Evolution · Quantitative Biology 2022-11-30 Nazmi Burak Budanur , Björn Hof

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

The COVID-19 pandemic has been characterised by multiple waves of transmission driven by interventions and emerging variants, challenging epidemic models that assume gradually evolving transmission dynamics. We propose a class of…

Applications · Statistics 2026-05-05 Patrick Aschermayr , Konstantinos Kalogeropoulos , Nikolaos Demiris

The COVID-19 pandemic has brought forth the importance of epidemic forecasting for decision makers in multiple domains, ranging from public health to the economy as a whole. While forecasting epidemic progression is frequently…

Machine Learning · Computer Science 2022-07-21 Alexander Rodríguez , Harshavardhan Kamarthi , Pulak Agarwal , Javen Ho , Mira Patel , Suchet Sapre , B. Aditya Prakash

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemination of contradictory model predictions has highlighted…

Populations and Evolution · Quantitative Biology 2020-06-26 Gemma Massonis , Julio R. Banga , Alejandro F. Villaverde

Within a short period of time, COVID-19 grew into a world-wide pandemic. Transmission by pre-symptomatic and asymptomatic viral carriers rendered intervention and containment of the disease extremely challenging. Based on reported infection…

Populations and Evolution · Quantitative Biology 2021-02-24 Liang Tian , Xuefei Li , Fei Qi , Qian-Yuan Tang , Viola Tang , Jiang Liu , Zhiyuan Li , Xingye Cheng , Xuanxuan Li , Yingchen Shi , Haiguang Liu , Lei-Han Tang

Scientific advice to the UK government throughout the COVID-19 pandemic has been informed by ensembles of epidemiological models provided by members of the Scientific Pandemic Influenza group on Modelling (SPI-M). Among other applications,…

Applications · Statistics 2021-08-13 D. S. Silk , V. E. Bowman , D. Semochkina , U. Dalrymple , D. C. Woods

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

Populations and Evolution · Quantitative Biology 2021-05-18 G. Albi , L. Pareschi , M. Zanella

In this paper, we develop an extension of standard epidemiological models, suitable for COVID-19. This extension incorporates the transmission due to pre-symptomatic or asymptomatic carriers of the virus. Furthermore, this model also…

Populations and Evolution · Quantitative Biology 2020-11-20 Anirban Ghatak , Shivshanker Singh Patel , Soham Bonnerjee , Subhrajyoty Roy

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

Methodology · Statistics 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li