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Motivated by present activities in (statistical) physics directed towards biological evolution, we review the interplay of three evolutionary forces: mutation, selection, and genetic drift. The review addresses itself to physicists and…

Statistical Mechanics · Physics 2016-11-23 Ellen Baake , Wilfried Gabriel

Unraveling the evolutionary forces shaping bacterial diversity can today be tackled using a growing amount of genomic data. While the genome of eukaryotes is highly stable, bacterial genomes from cells of the same species highly vary in…

Populations and Evolution · Quantitative Biology 2015-03-19 Franz Baumdicker , Peter Pfaffelhuber

Rich information on the prebiotic evolution is still stored in contemporary genomic data. The statistical mechanism at the sequence level may play a significant role in the prebiotic evolution. Based on statistical analysis of genome…

Other Quantitative Biology · Quantitative Biology 2018-07-12 Dirson Jian Li

The Extended Evolutionary Synthesis (EES) is beginning to fulfill the whole promise of Darwinian insight through its extension of evolutionary understanding from the biological domain to include cultural information evolution. Several…

Populations and Evolution · Quantitative Biology 2019-07-17 Cameron M. Smith , Liane Gabora , William Gardner-O'Kearney

This study introduces a novel theoretical framework, the Stacked Autoencoder Evolution Hypothesis, which proposes that biological evolutionary systems operate through multi-layered self-encoding and decoding processes, analogous to stacked…

Neural and Evolutionary Computing · Computer Science 2026-02-03 Hiroyuki Iizuka

Languages and genes are both transmitted from generation to generation, with opportunity for differential reproduction and survivorship of forms. Here we apply a rigorous inference framework, drawn from population genetics, to distinguish…

Populations and Evolution · Quantitative Biology 2017-11-07 Christopher A. Ahern , Mitchell G. Newberry , Robin Clark , Joshua B. Plotkin

We explore the connection between evolution and large-deviation theory. To do so, we study evolutionary dynamics in which individuals experience mutations, reproduction, and selection using variants of the Moran model. We show that, in the…

Populations and Evolution · Quantitative Biology 2026-01-09 Sara Dal Cengio , Quentin Laurenceau , Vivien Lecomte , Charline Smadi , Julien Tailleur

This piece serves two purposes. Firstly, it aims at elucidating the role of epistasis in shaping, at a molecular level, the evolutionary paths of proteins, as well as the extent to which these epistatic effects are the outcome of an…

Populations and Evolution · Quantitative Biology 2025-08-01 Jorge A. Vila

How mutations accumulate in genomes is the central question of molecular evolution theories, however our understanding of this process is far from complete. Drake's rule is a notoriously universal property of genomes from microbes to…

Populations and Evolution · Quantitative Biology 2014-09-22 Alexey A. Shadrin , Dmitri V. Parkhomchuk

Biological and social systems are structured at multiple scales, and the incentives of individuals who interact in a group may diverge from the collective incentive of the group as a whole. Mechanisms to resolve this tension are responsible…

Populations and Evolution · Quantitative Biology 2023-05-31 Daniel B. Cooney , Simon A. Levin , Yoichiro Mori , Joshua B. Plotkin

Reputed intractable, the question of the origin of viruses has long been neglected. In the modern literature 'Virus evolution' has come to refer to study more akin to population genetics, such as the world-wide scrutiny on new polymorphisms…

Populations and Evolution · Quantitative Biology 2007-05-23 Jean-Michel Claverie

A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards…

Biomolecules · Quantitative Biology 2008-05-06 Denis A. Semenov

This chapter synthesizes evidence from cognitive science, evolutionary theory, anthropology, psychological studies, and computational models for a complex systems inspired theory of creativity, and its role in cultural evolution. Creativity…

Physics and Society · Physics 2024-06-25 Liane Gabora

An increasing number of dissident voices claim that the standard neo-Darwinian view of genes as 'leaders' and phenotypes as 'followers' during the process of adaptive evolution should be turned on its head. This idea is older than the…

Populations and Evolution · Quantitative Biology 2015-03-10 Mauro Santos , Eörs Szathmáry , José F. Fontanari

A previous report claimed no evidence of transgenerational epigenetic inheritance in a mouse model of in utero environmental exposure, based on the observation that gene expression changes observed in the germ cells of G1 and G2 male fetus…

Genomics · Quantitative Biology 2016-06-29 Abhay Sharma

Developmental bias plays a major role in phenotypic evolution. Some researchers have argued that phenotypes, regulated by development, can only evolve along restricted trajectory under certain scenarios, such as the case for mammalian molar…

Populations and Evolution · Quantitative Biology 2023-11-15 Yue Zhang

Gene-sharing networks provide a powerful framework to study the evolution of viruses and mobile genetic elements. These bipartite networks, which link genes to the genomes that contain them, exhibit characteristic degree distributions: a…

Populations and Evolution · Quantitative Biology 2026-04-16 Jaime Iranzo , Pedro Jódar , Eugene V. Koonin , Susanna Manrubia , José A. Cuesta

The controversy concerning both the definition of the species and methods for inferring the boundaries and numbers of species has occupied biologists for centuries, and the debate itself has become known as the species problem. The modern…

Other Quantitative Biology · Quantitative Biology 2010-04-20 Yan Huang

Many organisms live in populations structured by space and by class, exhibit plastic responses to their social partners, and are subject to non-additive ecological and fitness effects. Social evolution theory has long recognized that all of…

Populations and Evolution · Quantitative Biology 2014-04-24 Jeremy Van Cleve , Erol Akçay

Evolution in changing environments is an important, but little studied aspect of the theory of evolution. The idea of adaptive walks in fitness landscapes has triggered a vast amount of research and has led to many important insights about…

Biological Physics · Physics 2007-05-23 Claus O. Wilke