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Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Willmer Rafell Quinones Robles , Sakonporn Noree , Jongwoo Kim , Young Sin Ko , Bryan Wong , Mun Yong Yi

Accurate diagnosis of disease often depends on the exhaustive examination of Whole Slide Images (WSI) at microscopic resolution. Efficient handling of these data-intensive images requires lossy compression techniques. This paper…

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

Self-supervised learning (SSL) approaches have achieved great success when the amount of labeled data is limited. Within SSL, models learn robust feature representations by solving pretext tasks. One such pretext task is contrastive…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Jamshid Hassanpour , Vinkle Srivastav , Didier Mutter , Nicolas Padoy

Learning similarity is a key aspect in medical image analysis, particularly in recommendation systems or in uncovering the interpretation of anatomical data in images. Most existing methods learn such similarities in the embedding space…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Sukesh Adiga , Jose Dolz , Herve Lombaert

State-of-the-art frameworks in self-supervised learning have recently shown that fully utilizing transformer-based models can lead to performance boost compared to conventional CNN models. Striving to maximize the mutual information of two…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Jiho Jang , Seonhoon Kim , Kiyoon Yoo , Chaerin Kong , Jangho Kim , Nojun Kwak

In Recent Years, Digital Technologies Have Made Significant Strides In Augmenting-Human-Health, Cognition, And Perception, Particularly Within The Field Of Computational-Pathology. This Paper Presents A Novel Approach To Enhancing The…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Xiaoqian Hu

Knowledge distillation is an effective approach to transferring knowledge from a teacher neural network to a student target network for satisfying the low-memory and fast running requirements in practice use. Whilst being able to create…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Xu Lan , Xiatian Zhu , Shaogang Gong

Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumour regions and reflecting intrinsic morphological heterogeneity. However, most existing approaches rely on a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zahra Rahimi Afzal , Wataru Uegami , Saghir Alfasly , Saba Yasir , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

Simplicity Bias (SB) is a phenomenon that deep neural networks tend to rely favorably on simpler predictive patterns but ignore some complex features when applied to supervised discriminative tasks. In this work, we investigate SB in…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Xiu-Shen Wei , Xuhao Sun , Yang Shen , Anqi Xu , Peng Wang , Faen Zhang

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Task-specific deep learning models in histopathology offer promising opportunities for improving diagnosis, clinical research, and precision medicine. However, development of such models is often limited by availability of high-quality…

With the excellent representation capabilities of Pre-Trained Models (PTMs), remarkable progress has been made in non-rehearsal Class-Incremental Learning (CIL) research. However, it remains an extremely challenging task due to three…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Jiawei Zhan , Jun Liu , Jinlong Peng , Xiaochen Chen , Bin-Bin Gao , Yong Liu , Chengjie Wang

Artificial intelligence algorithms have demonstrated their image classification and segmentation ability in the past decade. However, artificial intelligence algorithms perform less for actual clinical data than those used for simulations.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Mostafa Hajighasemlou , Samad Sheikhaei , Hamid Soltanian-Zadeh

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Blood vessel segmentation in medical imaging is one of the essential steps for vascular disease diagnosis and interventional planning in a broad spectrum of clinical scenarios in image-based medicine and interventional medicine.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Boah Kim , Yujin Oh , Bradford J. Wood , Ronald M. Summers , Jong Chul Ye

Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Linhao Qu , Xiaoyuan Luo , Shaolei Liu , Manning Wang , Zhijian Song

Supervised deep learning models depend on massive labeled data. Unfortunately, it is time-consuming and labor-intensive to collect and annotate bitemporal samples containing desired changes. Transfer learning from pre-trained models is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Hao Chen , Wenyuan Li , Song Chen , Zhenwei Shi