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Diffusion models are primarily trained for image synthesis, yet their denoising trajectories encode rich, spatially aligned visual priors. In this paper, we demonstrate that these priors can be utilized for text-conditioned semantic and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Haoxiao Wang , Antao Xiang , Haiyang Sun , Peilin Sun , Changhao Pan , Yifu Chen , Minjie Hong , Weijie Wang , Shuang Chen , Yue Chen , Zhou Zhao

3D delineation of anatomical structures is a cardinal goal in medical imaging analysis. Prior to deep learning, statistical shape models that imposed anatomical constraints and produced high quality surfaces were a core technology. Prior to…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Ashwin Raju , Shun Miao , Dakai Jin , Le Lu , Junzhou Huang , Adam P. Harrison

Many self-supervised denoising approaches have been proposed in recent years. However, these methods tend to overly smooth images, resulting in the loss of fine structures that are essential for medical applications. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Basar Demir , Yikang Liu , Xiao Chen , Eric Z. Chen , Lin Zhao , Boris Mailhe , Terrence Chen , Shanhui Sun

Once deployed, medical image analysis methods are often faced with unexpected image corruptions and noise perturbations. These unknown covariate shifts present significant challenges to deep learning based methods trained on "clean" images.…

Machine Learning · Computer Science 2025-07-01 Xing Shen , Hengguan Huang , Brennan Nichyporuk , Tal Arbel

Medical image segmentation has been significantly advanced with the rapid development of deep learning (DL) techniques. Existing DL-based segmentation models are typically discriminative; i.e., they aim to learn a mapping from the input…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Tao Chen , Chenhui Wang , Zhihao Chen , Yiming Lei , Hongming Shan

Multimodal medical image fusion (MMIF) extracts the most meaningful information from multiple source images, enabling a more comprehensive and accurate diagnosis. Achieving high-quality fusion results requires a careful balance of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Dan He , Weisheng Li , Guofen Wang , Yuping Huang , Shiqiang Liu

Denoising diffusion probabilistic models (DDPMs) (Ho et al. 2020) have shown impressive results on image and waveform generation in continuous state spaces. Here, we introduce Discrete Denoising Diffusion Probabilistic Models (D3PMs),…

Machine Learning · Computer Science 2023-02-23 Jacob Austin , Daniel D. Johnson , Jonathan Ho , Daniel Tarlow , Rianne van den Berg

Reducing the radiation dose in computed tomography (CT) is important to mitigate radiation-induced risks. One option is to employ a well-trained model to compensate for incomplete information and map sparse-view measurements to the CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Xiaoyue Li , Kai Shang , Gaoang Wang , Mark D. Butala

Dataset expansion can effectively alleviate the problem of data scarcity for medical image segmentation, due to privacy concerns and labeling difficulties. However, existing expansion algorithms still face great challenges due to their…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 Shitong Shao , Xiaohan Yuan , Zhen Huang , Ziming Qiu , Shuai Wang , Kevin Zhou

Supervised deep learning for semantic segmentation has achieved excellent results in accurately identifying anatomical and pathological structures in medical images. However, it often requires large annotated training datasets, which limits…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Luca Ciampi , Gabriele Lagani , Giuseppe Amato , Fabrizio Falchi

Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

This research presents a novel framework for the compression and decompression of medical images utilizing the Latent Diffusion Model (LDM). The LDM represents advancement over the denoising diffusion probabilistic model (DDPM) with a…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 InChan Hwang , MinJae Woo

This report presents the comprehensive implementation, evaluation, and optimization of Denoising Diffusion Probabilistic Models (DDPMs) and Denoising Diffusion Implicit Models (DDIMs), which are state-of-the-art generative models. During…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Jaineet Shah , Michael Gromis , Rickston Pinto

Amodal Instance Segmentation (AIS) presents an intriguing challenge, including the segmentation prediction of both visible and occluded parts of objects within images. Previous methods have often relied on shape prior information gleaned…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Minh Tran , Khoa Vo , Tri Nguyen , Ngan Le

Precise boundary segmentation of volumetric images is a critical task for image-guided diagnosis and computer-assisted intervention, especially for boundary confusion in clinical practice. However, U-shape networks cannot effectively…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Xin You , Ming Ding , Minghui Zhang , Hanxiao Zhang , Yi Yu , Jie Yang , Yun Gu

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

Three-dimensional (3D) medical image enhancement, including denoising and super-resolution, is critical for clinical diagnosis in CT, PET, and MRI. Although diffusion models have shown remarkable success in 2D medical imaging, scaling them…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hongxu Jiang , Fei Li , Boxiao Yu , Ying Zhang , Kaleb Smith , Kuang Gong , Wei Shao

We propose a novel unpaired image-to-image translation method that uses denoising diffusion probabilistic models without requiring adversarial training. Our method, UNpaired Image Translation with Denoising Diffusion Probabilistic Models…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Hiroshi Sasaki , Chris G. Willcocks , Toby P. Breckon

Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Xingjian Tang , Jingwei Guan , Linge Li , Ran Shi , Youmei Zhang , Mengye Lyu , Li Yan
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