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Medication recommendations aim to generate safe and effective medication sets from health records. However, accurately recommending medications hinges on inferring a patient's latent clinical condition from sparse and noisy observations,…

Information Retrieval · Computer Science 2026-03-20 Xiangxu Zhang , Xiao Zhou , Hongteng Xu , Jianxun Lian

Unsupervised Domain Adaptation (UDA) is essential for deploying medical segmentation models across diverse clinical environments. Existing methods are fundamentally limited, suffering from semantically unaware feature alignment that results…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Linkuan Zhou , Yinghao Xia , Yufei Shen , Xiangyu Li , Wenjie Du , Cong Cong , Leyi Wei , Ran Su , Qiangguo Jin

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

Medication recommendation is a crucial task for assisting physicians in making timely decisions from longitudinal patient medical records. However, real-world EHR data present significant challenges due to the presence of rarely observed…

Artificial Intelligence · Computer Science 2025-08-15 Yan Ting Chok , Soyon Park , Seungheun Baek , Hajung Kim , Junhyun Lee , Jaewoo Kang

Medication recommender is to suggest appropriate medication combinations based on a patient's health history, e.g., diagnoses and procedures. Existing works represent different diagnoses/procedures well separated by one-hot encodings.…

Information Retrieval · Computer Science 2024-11-06 Yuliang Liang , Yuting Liu , Yizhou Dang , Enneng Yang , Guibing Guo , Wei Cai , Jianzhe Zhao , Xingwei Wang

Electronic Health Records (EHR) have become a valuable resource for a wide range of predictive tasks in healthcare. However, existing approaches have largely focused on inter-visit event predictions, overlooking the importance of…

Machine Learning · Computer Science 2025-04-01 Yuyang Liang , Yankai Chen , Yixiang Fang , Laks V. S. Lakshmanan , Chenhao Ma

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

Machine Learning · Computer Science 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

Predicting patient mortality is an important and challenging problem in the healthcare domain, especially for intensive care unit (ICU) patients. Electronic health notes serve as a rich source for learning patient representations, that can…

Computation and Language · Computer Science 2019-10-16 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

Efficient and fast reconstruction of anatomical structures plays a crucial role in clinical practice. Minimizing retrieval and processing times not only potentially enhances swift response and decision-making in critical scenarios but also…

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

Machine Learning · Statistics 2019-09-09 Bryan Lim , Mihaela van der Schaar

Drug similarity has been studied to support downstream clinical tasks such as inferring novel properties of drugs (e.g. side effects, indications, interactions) from known properties. The growing availability of new types of drug features…

Machine Learning · Computer Science 2018-05-01 Tengfei Ma , Cao Xiao , Jiayu Zhou , Fei Wang

Electronic health record (EHR) data is sparse and irregular as it is recorded at irregular time intervals, and different clinical variables are measured at each observation point. In this work, we propose a multi-view features integration…

Machine Learning · Computer Science 2021-01-27 Yurim Lee , Eunji Jun , Heung-Il Suk

Historical prescriptions and selected candidate drugs relevant to the current visit serve as important references for medication recommendation. However, in the absence of explicit intrinsic principles for semantic composition, existing…

Computational Engineering, Finance, and Science · Computer Science 2026-01-28 Yanda Wang , Weitong Chen , Chao Tan , Ian Nabney , Lin Yue , Genlin Ji

Medication recommendation is a crucial task in healthcare, especially for patients with complex medical conditions. However, existing methods often struggle to effectively balance the reuse of historical medications with the introduction of…

Artificial Intelligence · Computer Science 2025-07-08 Feiyue Wu , Tianxing Wu , Shenqi Jing

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

Machine Learning · Computer Science 2021-03-29 Weicheng Zhu , Narges Razavian

Clinical event sequences consist of thousands of clinical events that represent records of patient care in time. Developing accurate prediction models for such sequences is of a great importance for defining representations of a patient…

Machine Learning · Computer Science 2021-04-07 Jeong Min Lee , Milos Hauskrecht

We propose a new method for modelling simple longitudinal data. We aim to do this in a flexible manner (without restrictive assumptions about the shapes of individual trajectories), while exploiting structural similarities between the…

Methodology · Statistics 2024-09-24 Helen Ogden

Patient healthcare utilization consists of irregularly time-stamped events, such as outpatient visits, inpatient admissions, and emergency encounters, forming individualized care trajectories. Modeling these trajectories is crucial for…

Machine Learning · Computer Science 2026-04-08 Saumya Pandey , Varun Chandola
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