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We present a theoretical study on pattern formation occurring in miscible fluids reacting by a second-order reaction $A + B \to S$ in a vertical Hele-Shaw cell under constant gravity. We have recently reported that concentration-dependent…

Fluid Dynamics · Physics 2019-09-25 Dmitry Bratsun

The replicator equation is ubiquitous for many areas of mathematical biology. One of major shortcomings of this equation is that it does not allow for an explicit spatial structure. Here we review analytical approaches to include spatial…

Populations and Evolution · Quantitative Biology 2011-05-06 Artem S. Novozhilov , Vladimir P. Posvyanskii , Alexander S. Bratus

We present and analyse a model for cell signalling processes in biological tissues. The model includes diffusion and nonlinear reactions on the cell surfaces, and both inter- and intracellular signalling. Using techniques from the theory of…

Analysis of PDEs · Mathematics 2020-03-12 Mariya Ptashnyk , Chandrasekhar Venkataraman

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

Serotonin (5-hydroxytryptamine) is a major neurotransmitter whose release from densely distributed serotonergic varicosities shapes plasticity and network integration throughout the brain, yet its extracellular dynamics remain poorly…

Tissues and Organs · Quantitative Biology 2026-05-21 Merlin Pelz , Skirmantas Janusonis , Gregory Handy

The macroscopic behavior of the solution of a coupled system of partial differential equations arising in the modeling of reaction-diffusion processes in periodic porous media is analyzed. Our mathematical model can be used for studying…

Analysis of PDEs · Mathematics 2019-06-19 G. Cardone , C. Perugia , C. Timofte

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Reaction-diffusion processes can be adopted to model a large number of dynamics on complex networks, such as transport processes or epidemic outbreaks. In most cases, however, they have been studied from a fermionic perspective, in which…

Statistical Mechanics · Physics 2008-10-21 Andrea Baronchelli , Michele Catanzaro , Romualdo Pastor-Satorras

We develop a statistical toolbox for a quantitative model evaluation of stochastic reaction-diffusion systems modeling space-time evolution of biophysical quantities on the intracellular level. Starting from space-time data $X_N(t,x)$, as,…

Methodology · Statistics 2023-07-14 Gregor Pasemann , Carsten Beta , Wilhelm Stannat

Reactions with enzymes are critical in biochemistry, where the enzymes act as catalysis in the process. One of the most used mechanisms for modeling enzyme-catalyzed reactions is the Michaelis-Menten (MM) kinetic. In the ODE level, i.e.…

Analysis of PDEs · Mathematics 2023-03-15 Bao Quoc Tang , Bao-Ngoc Tran

A key problem in modelling the evolution dynamics of infectious diseases is the mathematical representation of the mechanism of transmission of the contagion. Models with a finite number of subpopulations can be described via systems of…

Optimization and Control · Mathematics 2017-03-09 Sebastian Anita , Vincenzo Capasso

In modeling the inflammatory response to a lesion in an artery wall, there are a number of chemotactic mechanisms going on within the wall layer that lead to an arterial plaque. We introduce a rather reduced model of these dynamic…

Analysis of PDEs · Mathematics 2015-11-10 Jonathan Bell , Animikh Biswas

We provide a numerical study of the macroscopic model of [3] derived from an agent-based model for a system of particles interacting through a dynamical network of links. Assuming that the network remodelling process is very fast, the…

Lattice-based stochastic simulators are commonly used to study biological reaction-diffusion processes. Some of these schemes that are based on the reaction-diffusion master equation (RDME), can simulate for extended spatial and temporal…

Quantitative Methods · Quantitative Biology 2018-10-03 Wei-Xiang Chew , Kazunari Kaizu , Masaki Watabe , Sithi V. Muniandy , Koichi Takahashi , Satya N. V. Arjunan

The reversible reactions like A+B <-> C in the many-component diffusive system affect the diffusive properties of the constituents. The effective conjugation of irreversible processes of different dimensionality takes place due to the…

Other Condensed Matter · Physics 2007-05-23 Serge Shpyrko , Vladimir M. Sysoev

We present a spatially-extended system of chemical reactions exhibiting adaptation to time-dependent influxes of reactants. Here adaptation is defined as improved reproductive success, namely the ability of one of the many locally stable…

Statistical Mechanics · Physics 2025-12-02 Olivier Rivoire , Guy Bunin

We present spatio-temporal characteristics of spreading depolarizations (SD) in two experimental systems: retracting SD wave segments observed with intrinsic optical signals in chicken retina, and spontaneously occurring re-entrant SD waves…

Dynamical processes on networks are currently being considered in different domains of cross-disciplinary interest. Reaction-diffusion systems hosted on directed graphs are in particular relevant for their widespread applications, from…

Statistical Mechanics · Physics 2016-04-06 Silvia Contemori , Francesca Di Patti , Duccio Fanelli , Filippo Miele

A nonlinear cross-diffusion epidemic with a time-dependent Susceptible-Infected-Recovered-Died system is proposed in this paper. This system is derived from kinetic theory model by multiscale approach, which leads to an equivalent system…

Populations and Evolution · Quantitative Biology 2021-09-01 Mohamed Zagour

In this paper we consider mathematical modeling of the dynamics of self-organized patterning of spatially confined human embryonic stem cells (hESCs) treated with BMP4 (gastruloids) described in recent experimental works. In the first part…

Analysis of PDEs · Mathematics 2021-01-12 Prajakta Bedekar , Ilya Timofeyev , Aryeh Warmflash , Misha Perepelitsa