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To make full use of photocathode material and improve its quantum efficiency lifetime, it can be necessary to operate laser away from the cathode center in photoinjectors. In RF guns, the off-axis emitted beam will see a time-dependent RF…

Accelerator Physics · Physics 2016-12-21 Rui-Xuan Huang , Chad Mitchell , Qi-Ka Jia , Christos Papadopoulos , Fernando Sannibale

Purpose: Patient-specific ridge filters can modulate proton energy to obtain a conformal dose. We describe a new framework for optimization of filter design and spot maps to meet the unique demands of FLASH radiotherapy. We demonstrate an…

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Medical Physics · Physics 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

Background and Purpose: Increasing the number of arcs in volumetric modulated arc therapy (VMAT) allows for better intensity modulation and may improve plan quality. However, this leads to longer delivery times, which may cause patient…

Medical Physics · Physics 2025-10-31 Nathan Torelli , Madalyne Day , Jan Unkelbach

This research considers potential dose increase in target due to cisplatin (Pt) concentration and radiation type. Cisplatin concentrations from 0.003 to 120 mM were used. Monte-Carlo simulation of Linear accelerator (Elekta Synergy) and…

Medical Physics · Physics 2020-08-26 A. A. Baulin

Accurate fluence map prediction is essential in intensity-modulated radiation therapy (IMRT) to maximize tumor coverage while minimizing dose to healthy tissues. Conventional optimization is time-consuming and dependent on planner…

Image and Video Processing · Electrical Eng. & Systems 2025-11-13 Ujunwa Mgboh , Rafi Sultan , Dongxiao Zhu , Joshua Kim

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Beam orientation optimization (BOO) is a key component in the process of IMRT treatment planning. It determines to what degree one can achieve a good treatment plan quality in the subsequent plan optimization process. In this paper, we have…

Medical Physics · Physics 2015-05-27 Xun Jia , Chunhua Men , Yifei Lou , Steve B. Jiang

Radio interferometers consisting of identical antennas arranged on a regular lattice permit fast Fourier transform beamforming, which reduces the correlation cost from $\mathcal{O}(n^2)$ in the number of antennas to $\mathcal{O}(n\log n)$.…

Instrumentation and Methods for Astrophysics · Physics 2019-05-20 Kiyoshi W. Masui , J. Richard Shaw , Cherry Ng , Kendrick M. Smith , Keith Vanderlinde , Adiv Paradise

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

We present flattened convolutional neural networks that are designed for fast feedforward execution. The redundancy of the parameters, especially weights of the convolutional filters in convolutional neural networks has been extensively…

Neural and Evolutionary Computing · Computer Science 2015-11-23 Jonghoon Jin , Aysegul Dundar , Eugenio Culurciello

Purpose: A Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) are presented for a modified ultra-high dose-rate electron FLASH radiotherapy (eFLASH-RT) LINAC. Methods: The gantry…

Laser frequency combs are fast becoming critical to reaching the highest radial velocity precisions. One shortcoming is the highly variable brightness of the comb lines across the spectrum (up to 4-5 orders of magnitude). This can result in…

Stereotactic body radiotherapy (SBRT) is characterized by delivering a high amount of dose in a short period of time. In SBRT the dose is delivered using open fields (e.g., beam's-eye-view) known as "apertures". Mathematical methods can be…

Medical Physics · Physics 2015-06-15 Hamed Yarmand , David Craft

Adapting Foundation Models (FMs) for downstream tasks through Federated Learning (FL) emerges a promising strategy for protecting data privacy and valuable FMs. Existing methods fine-tune FM by allocating sub-FM to clients in FL, however,…

Machine Learning · Computer Science 2024-04-30 Zhaopeng Peng , Xiaoliang Fan , Yufan Chen , Zheng Wang , Shirui Pan , Chenglu Wen , Ruisheng Zhang , Cheng Wang

Purpose: To verify dose delivery and quality assurance of volumetric modulated arc therapy (VMAT) for head and neck cancer. Method: The Imaging and Radiation Oncology Core Houston (IROC-H) head and neck phantom with thermo- luminescent…

As the large language models (LLMs) grow in size each day, efficient training and fine-tuning has never been as important as nowadays. This resulted in the great interest in parameter efficient fine-tuning (PEFT), and effective methods…

Machine Learning · Computer Science 2025-11-04 Dhananjaya Gowda , Seoha Song , Junhyun Lee , Harshith Goka

Three-dimensional (3D) ultrasound promises various medical applications for abdominal, obstetrics, and breast imaging. However, ultrasound matrix arrays have extremely high element counts limiting their field of view (FOV). Current reduced…

Signal Processing · Electrical Eng. & Systems 2026-04-17 Mick Gardner , Michael L. Oelze