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The Helfrich bending energy plays an important role in providing a mechanism for the conformation of a lipid vesicle in theoretical biophysics, which is governed by the principle of energy minimization over configurations of appropriate…

Soft Condensed Matter · Physics 2018-06-20 Yisong Yang

Tubular and membranous shapes display a wide range of morphologies that are difficult to analyze within a common framework. By generalizing the classical Helfrich energy of biomembranes, we model them as solutions to a curvature…

Quantitative Methods · Quantitative Biology 2021-03-10 Anna Song

The Helfrich energy is commonly used to model the elastic bending energy of lipid bilayers in membrane mechanics. The governing differential equations for certain geometric characteristics of the shape of the membrane can be obtained by…

Numerical Analysis · Mathematics 2020-05-27 P. Rangamani , A. Behzadan , M. Holst

Current quadratic smoothness energies for curved surfaces either exhibit distortions near the boundary due to zero Neumann boundary conditions, or they do not correctly account for intrinsic curvature, which leads to unnatural-looking…

Graphics · Computer Science 2020-04-29 Oded Stein , Alec Jacobson , Max Wardetzky , Eitan Grinspun

We investigate equilibrium configurations for surface energies which contain the squared $L^2$ norm of the difference of the mean curvature H and the spontaneous curvature $c_o$ coupled with the elastic energy of the boundary curve, which…

Differential Geometry · Mathematics 2021-07-28 Bennett Palmer , Alvaro Pampano

In this paper we introduce a mathematical model for small deformations induced by external forces of closed surfaces that are minimisers of Helfrich-type energies. Our model is suitable for the study of deformations of cell membranes…

Analysis of PDEs · Mathematics 2016-10-18 Charles M. Elliott , Hans Fritz , Graham Hobbs

The surface free energy of ideal hard rods near curved hard surfaces is determined to second order in curvature for surfaces of general shape. In accordance with previous results for spherical and cylindrical surfaces it is found that this…

Soft Condensed Matter · Physics 2009-10-31 B. Groh

Thin elastic sheets appear in systems ranging from graphene to biological membranes, where phenomena such as wrinkling, folding, and thermal fluctuations originate from geometric nonlinearities. These effects are treated within weakly…

Soft Condensed Matter · Physics 2025-12-04 Yael Cohen , Animesh Pandey , Yafei Zhang , Cy Maor , Michael Moshe

A model describing cell membranes as optimal shapes with regard to the $L^2$-deficit of their mean curvature to a given constant called spontaneous curvature is considered. It is shown that the corresponding energy functional is lower…

Differential Geometry · Mathematics 2023-11-01 Christian Scharrer

We theoretically study the elastic deformation of a fluid membrane induced by an adhering spherical colloidal particle within the framework of a Helfrich energy. Based on a full optimization of the membrane shape we find a continuous…

Soft Condensed Matter · Physics 2009-11-07 Markus Deserno , Thomas Bickel

We address the geometric Cauchy problem for surfaces associated to the membrane shape equation describing equilibrium configurations of vesicles formed by lipid bilayers. This is the Euler-Lagrange equation of the Canham-Helfrich-Evans…

Differential Geometry · Mathematics 2014-11-18 Gary R. Jensen , Emilio Musso , Lorenzo Nicolodi

We conduct a systematic exploration of the energy landscape of vesicle morphologies within the framework of the Helfrich model. Vesicle shapes are determined by minimizing the elastic energy subject to constraints of constant area and…

Soft Condensed Matter · Physics 2023-11-27 Rodrigo B. Reboucas , Hammad A. Faizi , Michael J. Miksis , Petia M. Vlahovska

Liquid crystals with molecules constrained to the tangent bundle of a curved surface show interesting phenomena resulting from the tight coupling of the elastic and bulk free energies of the liquid crystal with geometric properties of the…

Soft Condensed Matter · Physics 2021-03-17 Ingo Nitschke , Sebastian Reuther , Axel Voigt

Since the pioneering work of Canham and Helfrich, variational formulations involving curvature-dependent functionals, like the classical Willmore functional, have proven useful for shape analysis of biomembranes. We address minimizers of…

Analysis of PDEs · Mathematics 2012-07-24 Rustum Choksi , Marco Veneroni

Functionals involving surface curvature are important across a range of scientific disciplines, and their extrema are representative of physically meaningful objects such as atomic lattices and biomembranes. Inspired in particular by the…

Differential Geometry · Mathematics 2020-01-31 Anthony Gruber , Magdalena Toda , Hung Tran

Variational principles are developed within the framework of a spinor representation of the surface geometry to examine the equilibrium properties of a membrane or interface. This is a far-reaching generalization of the Weierstrass-Enneper…

Soft Condensed Matter · Physics 2012-02-17 Jemal Guven , Pablo Vázquez-Montejo

In [12], the authors studied a particular class of equilibrium solutions of the Helfrich energy which satisfy a second order condition called the reduced membrane equation. In this paper we develop and apply a second variation formula for…

Differential Geometry · Mathematics 2024-01-11 Bennett Palmer , Alvaro Pampano

A phase-field model that takes into account the bending energy of fluid vesicles is presented. The Canham-Helfrich model is derived in the sharp-interface limit. A dynamic equation for the phase-field has been solved numerically to find…

Soft Condensed Matter · Physics 2007-05-23 F. Campelo , A. Hernandez-Machado

We study the conditions on the physical parameters in the Helfrich bending energy of lipid bilayer vesicles. Among embedded surfaces with a biconcave axisymmetric shape, the variation equation is analyzed in detail. This leads to simple…

Analysis of PDEs · Mathematics 2007-05-23 Thomas Kwok-keung Au , Tom Yau-heng Wan

By means of Surface Evolver (Exp. Math,1,141 1992), a software package of brute-force energy minimization over a triangulated surface developed by the geometry center of University of Minnesota, we have numerically searched the…

Biological Physics · Physics 2009-10-31 Yan Jie , Liu Quan-Hui , Liu Ji-Xing , Ou-Yang Zhong-Can
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