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The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

Machine Learning · Computer Science 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma

Electronic health records (EHRs) contain a vast amount of high-dimensional multi-modal data that can accurately represent a patient's medical history. Unfortunately, most of this data is either unstructured or semi-structured, rendering it…

Computation and Language · Computer Science 2023-12-06 Ashwyn Sharma , David I. Feldman , Aneesh Jain

Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…

Quantitative Methods · Quantitative Biology 2022-04-18 Alan D. Kaplan , Uttara Tipnis , Jean C. Beckham , Nathan A. Kimbrel , David W. Oslin , Benjamin H. McMahon

Predicting patient mortality is an important and challenging problem in the healthcare domain, especially for intensive care unit (ICU) patients. Electronic health notes serve as a rich source for learning patient representations, that can…

Computation and Language · Computer Science 2019-10-16 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu , Yuan Luo

Phone recognition (PR) serves as the atomic interface for language-agnostic modeling for cross-lingual speech processing and phonetic analysis. Despite prolonged efforts in developing PR systems, current evaluations only measure…

Recent deep learning methods for fMRI-based diagnosis have achieved promising accuracy by modeling functional connectivity networks. However, standard approaches often struggle with noisy interactions, and conventional post-hoc attribution…

Machine Learning · Computer Science 2026-02-25 Kunyu Zhang , Yanwu Yang , Jing Zhang , Xiangjie Shi , Shujian Yu

Electronic health records arise from the complex interaction between patients and the healthcare system. This observation process of interactions, referred to as clinical presence, often impacts observed outcomes. When using electronic…

Machine Learning · Computer Science 2025-08-08 Vincent Jeanselme , Glen Martin , Matthew Sperrin , Niels Peek , Brian Tom , Jessica Barrett

Digital healthcare systems have enabled the collection of mass healthcare data in electronic healthcare records (EHRs), allowing artificial intelligence solutions for various healthcare prediction tasks. However, existing studies often…

Machine Learning · Computer Science 2025-08-27 Zi Cai , Yu Liu , Zhiyao Luo , Tingting Zhu

Disparities in access to healthcare have been well-documented in the United States, but their effects on electronic health record (EHR) data reliability and resulting clinical models are poorly understood. Using an All of Us dataset of…

Computers and Society · Computer Science 2024-12-17 Anna Zink , Hongzhou Luan , Irene Y. Chen

Electronic health records (EHR) data have considerable variability in data completeness across sites and patients. Lack of "EHR data-continuity" or "EHR data-discontinuity", defined as "having medical information recorded outside the reach…

Electronic health records (EHRs) are increasingly recognized as a cost-effective resource for patient recruitment in clinical research. However, how to optimally select a cohort from millions of individuals to answer a scientific question…

Methodology · Statistics 2023-12-14 Guanghao Zhang , Lauren J. Beesley , Bhramar Mukherjee , Xu Shi

Medical image segmentation is fundamental to clinical decision-making, yet existing models remain fragmented. They are usually trained on single knowledge sources and specific to individual tasks, modalities, or organs. This fragmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Bangwei Guo , Yunhe Gao , Meng Ye , Difei Gu , Yang Zhou , Leon Axel , Dimitris Metaxas

Time series imputation models have traditionally been developed using complete datasets with artificial masking patterns to simulate missing values. However, in real-world infrastructure monitoring, practitioners often encounter datasets…

Machine Learning · Computer Science 2025-06-26 Ryan Hildebrant , Rahul Bhope , Sharad Mehrotra , Christopher Tull , Nalini Venkatasubramanian

Objective: Temporal electronic health records (EHRs) can be a wealth of information for secondary uses, such as clinical events prediction or chronic disease management. However, challenges exist for temporal data representation. We…

Machine Learning · Computer Science 2024-06-11 Feng Xie , Han Yuan , Yilin Ning , Marcus Eng Hock Ong , Mengling Feng , Wynne Hsu , Bibhas Chakraborty , Nan Liu

Substantial increase in the use of Electronic Health Records (EHRs) has opened new frontiers for predictive healthcare. However, while EHR systems are nearly ubiquitous, they lack a unified code system for representing medical concepts.…

Machine Learning · Computer Science 2022-03-21 Kyunghoon Hur , Jiyoung Lee , Jungwoo Oh , Wesley Price , Young-Hak Kim , Edward Choi

This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…

Machine Learning · Computer Science 2025-02-05 Linglong Qian , Yiyuan Yang , Wenjie Du , Jun Wang , Richard Dobsoni , Zina Ibrahim

The presence of detailed clinical information in electronic health record (EHR) systems presents promising prospects for enhancing patient care through automated retrieval techniques. Nevertheless, it is widely acknowledged that accessing…

Information Retrieval · Computer Science 2024-09-13 Abderrahim Oussama Batouche , Eugen Czeizler , Miika Koskinen , Tuomas Mirtti , Antti Sakari Rannikko

Prediction Rule Ensembles (PREs) are robust and interpretable statistical learning techniques with potential for predictive analytics, yet their efficacy in the presence of missing data is untested. This study uses multiple imputation to…

Applications · Statistics 2024-10-22 Vincent Schroeder , Jakob Schwerter , Marjolein Fokkema , Philipp Doebler

Healthcare time series data is vital for monitoring patient activity but often contains noise and missing values due to various reasons such as sensor errors or data interruptions. Imputation, i.e., filling in the missing values, is a…

Machine Learning · Computer Science 2024-12-17 Lien P. Le , Xuan-Hien Nguyen Thi , Thu Nguyen , Michael A. Riegler , Pål Halvorsen , Binh T. Nguyen

Missing data is a persistent challenge in federated learning on electronic health records, particularly when institutions collect time-series data at varying temporal granularities. To address this, we propose Federated Markov Imputation…

Machine Learning · Computer Science 2025-09-26 Christoph Düsing , Philipp Cimiano