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Functional data analysis (FDA) methods have computational and theoretical appeals for some high dimensional data, but lack the scalability to modern large sample datasets. To tackle the challenge, we develop randomized algorithms for two…
Many rare diseases offer limited established treatment options, leading patients to switch therapies when new medications emerge. To analyze the impact of such treatment switches within the low sample size limitations of rare disease…
In traditional multivariate data analysis, dimension reduction and regression have been treated as distinct endeavors. Established techniques such as principal component regression (PCR) and partial least squares (PLS) regression…
This work is motivated by analyses of longitudinal data collected from participants in the Quebec Longitudinal Study of Child Development (QLSCD) and the Quebec Newborn Twin Study (QNTS) to identify important genetic predictors for…
Federated Learning (FL) has emerged as a promising solution in Edge Computing (EC) environments to process the proliferation of data generated by edge devices. By collaboratively optimizing the global machine learning models on distributed…
Generalized linear model or GLM constitutes a large class of models and essentially extends the ordinary linear regression by connecting the mean of the response variable with the covariate through appropriate link functions. On the other…
Federated learning (FL) research has made progress in developing algorithms for distributed learning of global models, as well as algorithms for local personalization of those common models to the specifics of each client's local data…
Analyzing longitudinal data in health studies is challenging due to sparse and error-prone measurements, strong within-individual correlation, missing data and various trajectory shapes. While mixed-effect models (MM) effectively address…
Typically, trials investigate the impact of either an individual-level intervention on participant outcomes, or the impact of a cluster-level intervention on participant outcomes. Factorial designs consider two (or more) treatments for each…
In many domains such as healthcare or finance, data often come in different assays or measurement modalities, with features in each assay having a common theme. Simply concatenating these assays together and performing prediction can be…
Mixtures of linear mixed models are widely used for modelling longitudinal data for which observation times differ between subjects. In typical applications, temporal trends are described using a basis expansion, with basis coefficients…
Measuring bias is key for better understanding and addressing unfairness in NLP/ML models. This is often done via fairness metrics which quantify the differences in a model's behaviour across a range of demographic groups. In this work, we…
We investigate the parameter estimation of regression models with fixed group effects, when the group variable is missing while group related variables are available. This problem involves clustering to infer the missing group variable…
Large Language Models (LLMs) are now state-of-the-art at summarization, yet the internal notion of importance that drives their information selections remains hidden. We propose to investigate this by combining behavioral and computational…
The use of principal component methods to analyze functional data is appropriate in a wide range of different settings. In studies of ``functional data analysis,'' it has often been assumed that a sample of random functions is observed…
A deep latent variable model is a powerful method for capturing complex distributions. These models assume that underlying structures, but unobserved, are present within the data. In this dissertation, we explore high-dimensional problems…
In many causal studies, outcomes are censored by death, in the sense that they are neither observed nor defined for units who die. In such studies, the focus is usually on the stratum of always survivors up to a single fixed time s.…
Human Sensing, a field that leverages technology to monitor human activities, psycho-physiological states, and interactions with the environment, enhances our understanding of human behavior and drives the development of advanced services…
Existing NLP datasets contain various biases that models can easily exploit to achieve high performances on the corresponding evaluation sets. However, focusing on dataset-specific biases limits their ability to learn more generalizable…
This paper develops a general causal inference method for treatment effects models with noisily measured confounders. The key feature is that a large set of noisy measurements are linked with the underlying latent confounders through an…