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The ability to estimate 3D human body pose and movement, also known as human pose estimation (HPE), enables many applications for home-based health monitoring, such as remote rehabilitation training. Several possible solutions have emerged…
Nuclear magnetism underpins areas such as medicine in magnetic resonance imaging (MRI). Hyperpolarization of nuclei enhances the quantity and quality of information that can be determined from these techniques by increasing their signal to…
Microfluidic systems hold great potential for the study of live microscopic cultures of cells, tissue samples, and small organisms. Integration of hyperpolarisation would enable quantitative studies of metabolism in such volume limited…
Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique offering high-resolution 3D images and valuable insights into human tissue conditions. Even at present, the refinement of denoising methods for MRI remains a…
Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…
A portable NMR polarimeter system has been developed to measure the polarization of a polarized Hydrogen-Deuteride (HD) target for hadron photoproduction experiments at SPring-8. The polarized HD target is produced at the Research Center…
State-of-the-art magnetic resonance imaging uses hyperpolarized molecules to track metabolism in vivo, but large superconducting magnets are required, and the strong magnetic fields largely preclude measurement in the presence of conductive…
High Intensity Focused Ultrasound (HIFU) can be used to achieve a local temperature increase deep inside the human body in a non-invasive way. MRI guidance of the procedure allows in situ target definition. In addition, MRI can be used to…
MRI-guided High Intensity Focused Ultrasound (MRI-HIFU) is a promising method for the non-invasive ablation of pathological tissue in many organs, including mobile organs such as liver and kidney. The possibility to locally deposit thermal…
Recently, diagnosis, therapy and monitoring of human diseases involve a variety of imaging modalities, such as magnetic resonance imaging(MRI), computed tomography(CT), Ultrasound(US) and Positron-emission tomography(PET) as well as a…
Since the initial patent in 2001, the Magnetic Particle Imaging (MPI) community has been striving to develop an MPI scanner suitable for human applications. Numerous contributions from different research fields, regarding tracer…
The sensitivity of NMR and MRI can be boosted via hyperpolarization of nuclear spins. However, current methods are costly, polarization is relatively low, or applicability is limited. Here, we report a new hyperpolarization method combining…
Classifying hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is a critical step in treatment selection and prognosis evaluation for patients with liver diseases. Traditional histopathological diagnosis poses…
Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…
Magnetic resonance imaging (MRI) is an increasingly important tool for the diagnosis and treatment of prostate cancer. However, interpretation of MRI suffers from high inter-observer variability across radiologists, thereby contributing to…
Polarized light microscopy provides unique opportunities for analyzing the molecular order in man-made and natural materials, including biological structures inside living cells, tissues, and whole organisms. 20 years ago, the LC-PolScope…
Since the publication of our review article Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments in 2018, the technological and applicational landscape of the use of…
One of the distinct characteristics in radiologists' reading of multiparametric prostate MR scans, using reporting systems such as PI-RADS v2.1, is to score individual types of MR modalities, T2-weighted, diffusion-weighted, and dynamic…
Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two dynamic, but until recently quite distinct, fields of research. Recent developments in both areas increased their synergistic overlap. By microfluidic…
Cellular metabolic rate is a good indicator of the physiological state of cells and its changes, which can be measured by total heat flux accompanying metabolism. Chip calorimeters can provide label-free and high throughput measurements of…