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Accurate segmentation of Multiple Sclerosis (MS) lesions in longitudinal MRI scans is crucial for monitoring disease progression and treatment efficacy. Although changes across time are taken into account when assessing images in clinical…

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of…

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

Convolutional Neural Networks (CNNs) have shown remarkable progress in medical image segmentation. However, lesion segmentation remains a challenge to state-of-the-art CNN-based algorithms due to the variance in scales and shapes. On the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yanwen Li , Luyang Luo , Huangjing Lin , Pheng-Ann Heng , Hao Chen

Semantic segmentation is crucial in remote sensing, where high-resolution satellite images are segmented into meaningful regions. Recent advancements in deep learning have significantly improved satellite image segmentation. However, most…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Santiago Rivier , Carlos Hinojosa , Silvio Giancola , Bernard Ghanem

Skin lesion segmentation is a crucial step in dermatology for guiding clinical decision-making. However, existing methods for accurate, robust, and resource-efficient lesion analysis have limitations, including low performance and high…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Linxuan Fan , Juntao Jiang , Weixuan Liu , Zhucun Xue , Jiajun Lv , Jiangning Zhang , Yong Liu

Deep learning-based medical image segmentation technology aims at automatic recognizing and annotating objects on the medical image. Non-local attention and feature learning by multi-scale methods are widely used to model network, which…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Bo Wang , Lei Wang , Junyang Chen , Zhenghua Xu , Thomas Lukasiewicz , Zhigang Fu

Detecting brain lesions as abnormalities observed in magnetic resonance imaging (MRI) is essential for diagnosis and treatment. In the search of abnormalities, such as tumors and malformations, radiologists may benefit from computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Hassan Baker , Austin J. Brockmeier

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Segmentation of objects of interest is one of the central tasks in medical image analysis, which is indispensable for quantitative analysis. When developing machine-learning based methods for automated segmentation, manual annotations are…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Hang Li , Dong Wei , Shilei Cao , Kai Ma , Liansheng Wang , Yefeng Zheng

Dense prediction tasks such as segmentation and detection of pathological entities hold crucial clinical value in computational pathology workflows. However, obtaining dense annotations on large cohorts is usually tedious and expensive.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Jingwei Zhang , Saarthak Kapse , Ke Ma , Prateek Prasanna , Maria Vakalopoulou , Joel Saltz , Dimitris Samaras

Segmenting small lesions in medical images remains notoriously difficult. Most prior work tackles this challenge by either designing better architectures, loss functions, or data augmentation schemes; and collecting more labeled data. We…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Rachit Saluja , Asli Cihangir , Ruining Deng , Johannes C. Paetzold , Fengbei Liu , Mert R. Sabuncu

The success of deep learning heavily depends on the availability of large labeled training sets. However, it is hard to get large labeled datasets in medical image domain because of the strict privacy concern and costly labeling efforts.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Dewen Zeng , Yawen Wu , Xinrong Hu , Xiaowei Xu , Haiyun Yuan , Meiping Huang , Jian Zhuang , Jingtong Hu , Yiyu Shi

Training machine learning models to segment tumors and other anomalies in medical images is an important step for developing diagnostic tools but generally requires manually annotated ground truth segmentations, which necessitates…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Jay J. Yoo , Khashayar Namdar , Farzad Khalvati

Automatic segmentation of breast tumors from the ultrasound images is essential for the subsequent clinical diagnosis and treatment plan. Although the existing deep learning-based methods have achieved significant progress in automatic…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Xing Yang , Jian Zhang , Qijian Chen , Li Wang , Lihui Wang

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies
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