Related papers: Bayesian Evidence Synthesis for Modeling SARS-CoV-…
Infectious disease spread is a multi-scale process composed of within-host (biological) and between-host (social) drivers and disentangling them from each other is a central challenge in epidemiology. Here, we introduce VIBES, a multi-scale…
Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…
Classical compartmental models in epidemiology often assume a homogeneous population for simplicity, which neglects the inherent heterogeneity among individuals. This assumption frequently leads to inaccurate predictions when applied to…
The coronavirus disease (COVID-19) pandemic has changed our lives and still poses a challenge to science. Numerous studies have contributed to a better understanding of the pandemic. In particular, inhalation of aerosolised pathogens has…
Infectious epidemics can be simulated by employing dynamical processes as interactions on network structures. Here, we introduce techniques from the Multi-Agent System (MAS) domain in order to account for individual level characterization…
Assessing the practical identifiability of epidemic models is essential for determining whether parameters can be meaningfully estimated from observed data. Monte Carlo (MC) methods provide an accessible and intuitive framework; however,…
We propose a high dimensional Bayesian inference framework for learning heterogeneous dynamics of a COVID-19 model, with a specific application to the dynamics and severity of COVID-19 inside and outside long-term care (LTC) facilities. We…
Understanding how stochastic gene expression is regulated in biological systems using snapshots of single-cell transcripts requires state-of-the-art methods of computational analysis and statistical inference. A Bayesian approach to…
Stochastic epidemic models provide an interpretable probabilistic description of the spread of a disease through a population. Yet, fitting these models to partially observed data is a notoriously difficult task due to intractability of the…
In the present article a mathematical model is proposed to research the current coronavirus outbreak (SARS-CoV-2) in Paraguay, describing the multiple transmission paths in the infection dynamics, following the susceptible, exposed,…
In this paper we develop statistical methods for causal inference in epidemics. Our focus is in estimating the effect of social mobility on deaths in the Covid-19 pandemic. We propose a marginal structural model motivated by a modified…
In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…
The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…
In the wake of the SARS-CoV-2 pandemic, there has been heightened interest from applied mathematicians in infectious disease modelling. Modelling efforts often focus on predicting whether diseases are likely to be eliminated or, instead,…
We study a stochastic epidemic model consisting of elements (organisms in a community or cells in tissue) with fixed positions, in which damage or disease is transmitted by diffusing agents ("signals") emitted by infected individuals. The…
The evolution of epidemiological parameters, such as instantaneous reproduction number Rt, is important for understanding the transmission dynamics of infectious diseases. Current estimates of time-varying epidemiological parameters often…
The Covid-19 pandemic has taken millions of lives, demonstrating the tragedy and disruption of respiratory diseases, and how difficult they can be to manage. However, there is still significant debate in the scientific community as to which…
COVID-19 pandemic has reshaped our world in a timescale much shorter than what we can understand. Particularities of SARS-CoV-2, such as its persistence in surfaces and the lack of a curative treatment or vaccine against COVID-19, have…
We propose a stochastic SIR model, specified as a system of stochastic differential equations, to analyse the data of the Italian COVID-19 epidemic, taking also into account the under-detection of infected and recovered individuals in the…
Accurate forecasts of COVID-19 is central to resource management and building strategies to deal with the epidemic. We propose a heterogeneous infection rate model with human mobility for epidemic modeling, a preliminary version of which we…