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Quantifiable image patterns associated with disease progression and treatment response are critical tools for guiding individual treatment, and for developing novel therapies. Here, we show that unsupervised machine learning can identify a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Matthias Perkonigg , Nina Bastati , Ahmed Ba-Ssalamah , Peter Mesenbrink , Alexander Goehler , Miljen Martic , Xiaofei Zhou , Michael Trauner , Georg Langs

Cardiovascular diseases are becoming increasingly prevalent in modern society, with a profound impact on global health and well-being. These Cardiovascular disorders are complex and multifactorial, influenced by genetic predispositions,…

Computation and Language · Computer Science 2025-10-23 Kailai Yang , Yan Leng , Xin Zhang , Tianlin Zhang , Paul Thompson , Bernard Keavney , Maciej Tomaszewski , Sophia Ananiadou

Accurately predicting and detecting interstitial lung disease (ILD) patterns given any computed tomography (CT) slice without any pre-processing prerequisites, such as manually delineated regions of interest (ROIs), is a clinically…

Computer Vision and Pattern Recognition · Computer Science 2017-01-23 Mingchen Gao , Ziyue Xu , Le Lu , Adam P. Harrison , Ronald M. Summers , Daniel J. Mollura

Speech and language technologies offer valuable opportunities for supporting mental health assessment through objective and interpretable cues. We present a systematic feature-based analysis framework leveraging perceptually grounded…

Artificial Intelligence · Computer Science 2026-05-28 Vassilis Lyberatos , Edmund G. Dervakos , Eleni Adamidi , Athanasios Voulodimos , Giorgos Stamou

Purpose: Automatic methods are required for the early detection of hepatic steatosis to avoid progression to cirrhosis and cancer. Here, we developed a fully automated deep learning pipeline to quantify hepatic steatosis on non-contrast…

Quantitative Methods · Quantitative Biology 2022-02-08 Zhongyi Zhang , Jakob Weiss , Jana Taron , Roman Zeleznik , Michael T. Lu , Hugo J. W. L. Aerts

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

Phonocardiogram (PCG) analysis is vital for cardiovascular disease diagnosis, yet the scarcity of labeled pathological data hinders the capability of AI systems. To bridge this, we introduce H-LDM, a Hierarchical Latent Diffusion Model for…

Machine Learning · Computer Science 2026-02-13 Chenyang Xu , Siming Li , Hao Wang

Chronic Kidney Disease (CKD) constitutes a major global medical burden, marked by the gradual deterioration of renal function, which results in the impaired clearance of metabolic waste and disturbances in systemic fluid homeostasis. Owing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Anas Bin Ayub , Nilima Sultana Niha , Md. Zahurul Haque

Revealing the underlying causal mechanisms in the real world is crucial for scientific and technological progress. Despite notable advances in recent decades, the lack of high-quality data and the reliance of traditional causal discovery…

Machine Learning · Computer Science 2026-02-17 Huaming Du , Tao Hu , Yijie Huang , Yu Zhao , Guisong Liu , Tao Gu , Gang Kou , Carl Yang

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Enlarged lymph nodes (LNs) can provide important information for cancer diagnosis, staging, and measuring treatment reactions, making automated detection a highly sought goal. In this paper, we propose a new algorithm representation of…

Computer Vision and Pattern Recognition · Computer Science 2014-08-15 Ari Seff , Le Lu , Kevin M. Cherry , Holger Roth , Jiamin Liu , Shijun Wang , Joanne Hoffman , Evrim B. Turkbey , Ronald M. Summers

Addressing the challenge of limited labeled data in clinical settings, particularly in the prediction of fatty liver disease, this study explores the potential of graph representation learning within a semi-supervised learning framework.…

Machine Learning · Computer Science 2024-03-06 So Yeon Kim , Sehee Wang , Eun Kyung Choe

Graft-versus-host disease (GVHD) is a rare but often fatal complication in liver transplantation, with a very high mortality rate. By harnessing multi-modal deep learning methods to integrate heterogeneous and imbalanced electronic health…

Machine Learning · Computer Science 2025-11-18 Yushan Jiang , Shuteng Niu , Dongjin Song , Yichen Wang , Jingna Feng , Xinyue Hu , Liu Yang , Cui Tao

Identification of plant disease is usually done through visual inspection or during laboratory examination which causes delays resulting in yield loss by the time identification is complete. On the other hand, complex deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Nisar Ahmed , Hafiz Muhammad Shahzad Asif , Gulshan Saleem

Accurate detection of thyroid lesions is a critical aspect of computer-aided diagnosis. However, most existing detection methods perform only one feature extraction process and then fuse multi-scale features, which can be affected by noise…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Lingtao Wang , Jianrui Ding , Fenghe Tang , Chunping Ning

Automatic segmentation of the liver and its lesion is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically…

Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, and most public datasets contain no clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Chenjun Li , Laurin Lux , Alexander H. Berger , Martin J. Menten , Mert R. Sabuncu , Johannes C. Paetzold

Lymph node metastasis (LNM) is a significant prognostic factor in patients with head and neck cancer, and the ability to predict it accurately is essential for treatment optimization. PET and CT imaging are routinely used for LNM…

Patients with Frontotemporal Dementia (FTD) have impaired cognitive abilities, executive and behavioral traits, loss of language ability, and decreased memory capabilities. Based on the distinct patterns of cortical atrophy and symptoms,…

Artificial Intelligence · Computer Science 2021-04-13 Km Poonam , Rajlakshmi Guha , Partha P Chakrabarti