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Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…

Neurons and Cognition · Quantitative Biology 2025-10-23 Thomas Thebaud , Anna Favaro , Casey Chen , Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak

The quantification of liver fat as a diagnostic assessment of steatosis remains an important priority for noninvasive imaging systems. We derive a framework in which the unknown fat volume percentage can be estimated from a pair of…

Medical Physics · Physics 2021-09-10 Juvenal Ormachea , Kevin J. Parker

Accurate disease detection is of paramount importance for effective medical treatment and patient care. However, the process of disease detection is often associated with extensive medical testing and considerable costs, making it…

Machine Learning · Computer Science 2025-12-10 Haokun Zhao , Yingzhe Bai , Qingyang Xu , Lixin Zhou , Jianxin Chen , Jicong Fan

Liver landmarks provide crucial anatomical guidance to the surgeon during laparoscopic liver surgery to minimize surgical risk. However, the tubular structural properties of landmarks and dynamic intraoperative deformations pose significant…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Ruize Cui , Jiaan Zhang , Jialun Pei , Kai Wang , Pheng-Ann Heng , Jing Qin

Objectives- Several ultrasound measures have shown promise for assessment of steatosis compared to traditional B-scan, however clinicians may be required to integrate information across the parameters. Here, we propose an integrated…

Medical Physics · Physics 2024-04-03 Jihye Baek , Ahmed El Kaffas , Aya Kamaya , Kenneth Hoyt , Kevin J. Parker

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

Other Quantitative Biology · Quantitative Biology 2025-10-20 Syed Ibad Hasnain

Dental fluorosis is a chronic disease caused by long-term overconsumption of fluoride, which leads to changes in the appearance of tooth enamel. It is an important basis for early non-invasive diagnosis of endemic fluorosis. However, even…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Yun Wu , Hao Xu , Maohua Gu , Zhongchuan Jiang , Jun Xu , Youliang Tian

Cardiovascular disease (CVD) remains the foremost cause of mortality worldwide, underscoring the urgent need for intelligent and data-driven diagnostic tools. Traditional predictive models often struggle to generalize across heterogeneous…

Artificial Intelligence · Computer Science 2026-01-27 Rajan Das Gupta , Xiaobin Wu , Xun Liu , Jiaqi He

Purpose: In laparoscopic liver surgery (LLS), pre-operative information can be overlaid onto the intra-operative scene by registering a 3D pre-operative model to the intra-operative partial surface reconstructed from the laparoscopic video.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Zixin Yang , Richard Simon , Cristian A. Linte

Various imaging modalities are used in patient diagnosis, each offering unique advantages and valuable insights into anatomy and pathology. Computed Tomography (CT) is crucial in diagnostics, providing high-resolution images for precise…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Rabeya Tus Sadia , Jie Zhang , Jin Chen

Foodborne gastrointestinal (GI) illness is a common cause of ill health in the UK. However, many cases do not interact with the healthcare system, posing significant challenges for traditional surveillance methods. The growth of publicly…

Computation and Language · Computer Science 2025-03-14 Timothy Laurence , Joshua Harris , Leo Loman , Amy Douglas , Yung-Wai Chan , Luke Hounsome , Lesley Larkin , Michael Borowitz

The lungs are the essential organs of respiration, and this system is significant in the carbon dioxide and exchange between oxygen that occurs in human life. However, several lung diseases, which include pneumonia, tuberculosis, COVID-19,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Sajjad Saleem , Muhammad Imran Sharif

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

In histopathological image analysis, feature extraction for classification is a challenging task due to the diversity of histology features suitable for each problem as well as presence of rich geometrical structure. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Tiep H. Vu , Hojjat S. Mousavi , Vishal Monga , UK Arvind Rao , Ganesh Rao

Diabetic Retinopathy (DR) is a major cause of global blindness, necessitating early and accurate diagnosis. While deep learning models have shown promise in DR detection, their black-box nature often hinders clinical adoption due to a lack…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Masato Ito , Kaito Tanaka , Keisuke Matsuda , Aya Nakayama

Automatic detection of liver lesions in CT images poses a great challenge for researchers. In this work we present a deep learning approach that models explicitly the variability within the non-lesion class, based on prior knowledge of the…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Maayan Frid-Adar , Idit Diamant , Eyal Klang , Michal Amitai , Jacob Goldberger , Hayit Greenspan

This paper presents the Multimodal Laryngoscopic Video Analyzing System (MLVAS), a novel system that leverages both audio and video data to automatically extract key video segments and metrics from raw laryngeal videostroboscopic videos for…

Sound · Computer Science 2026-03-10 Yucong Zhang , Xin Zou , Jinshan Yang , Wenjun Chen , Juan Liu , Faya Liang , Ming Li

Accurate characterisation of visual attributes such as spiculation, lobulation, and calcification of lung nodules is critical in cancer management. The characterisation of these attributes is often subjective, which may lead to high inter-…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Xiaohang Fu , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

For a medical diagnosis, health professionals use different kinds of pathological ways to make a decision for medical reports in terms of patients medical condition. In the modern era, because of the advantage of computers and technologies,…

Machine Learning · Statistics 2021-06-08 Fahad B. Mostafa , Md Easin Hasan

Automatic segmentation of liver lesions is a fundamental requirement towards the creation of computer aided diagnosis (CAD) and decision support systems (CDS). Traditional segmentation approaches depend heavily upon hand-crafted features…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Lei Bi , Jinman Kim , Ashnil Kumar , Dagan Feng