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We demonstrate the feasibility of quantum computing for large-scale, realistic chemical systems through the development of a new interface using a quantum circuit simulator and CP2K, a highly efficient first-principles calculation software.…

Chemical Physics · Physics 2025-06-24 Tomoya Shiota , Klaas Gunst , Toshio Mori , Toru Shiozaki , Wataru Mizukami

With the rapid development of classical and quantum machine learning, a large number of machine learning frameworks have been proposed. However, existing machine learning frameworks usually only focus on classical or quantum, rather than…

We discuss a Quantum-Enhanced Computing Continuum, a heterogeneous, hybrid architecture that integrates quantum processing units (QPUs) within an Edge-Cloud-HPC fabric. Promote sustainability by shifting from performance to "energy-aware…

Emerging Technologies · Computer Science 2026-05-01 Carlos J. Barrios H. , Frédéric Le Mouël , Oscar Carrillo

Quantum computers can exploit a Hilbert space whose dimension increases exponentially with the number of qubits. In experiment, quantum supremacy has recently been achieved by the Google team by using a noisy intermediate-scale quantum…

Quantum Physics · Physics 2021-02-02 Suguru Endo , Zhenyu Cai , Simon C. Benjamin , Xiao Yuan

Deep learning is a modern approach to realize artificial intelligence. Many frameworks exist to implement the machine learning task; however, performance is limited by computing resources. Using a quantum computer to accelerate training is…

Quantum Physics · Physics 2019-01-29 Zhao-Yun Chen , Cheng Xue , Si-Ming Chen , Guo-Ping Guo

Machine Learning (ML) models are trained using historical data to classify new, unseen data. However, traditional computing resources often struggle to handle the immense amount of data, commonly known as Big Data, within a reasonable time…

Quantum Physics · Physics 2024-11-01 Minati Rath , Hema Date

As quantum computers become available to the general public, the need has arisen to train a cohort of quantum programmers, many of whom have been developing classical computer programs for most of their careers. While currently available…

High performance computing (HPC) and cloud have traditionally been separate, and presented in an adversarial light. The conflict arises from disparate beginnings that led to two drastically different cultures, incentive structures, and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-24 Vanessa Sochat , David Fox , Daniel Milroy

Quantum computing is a promising approach of computation that is based on equations from Quantum Mechanics. A simulator for quantum algorithms must be capable of performing heavy mathematical matrix transforms. The design of the simulator…

Emerging Technologies · Computer Science 2013-02-25 A. S. Tolba , M. Z. Rashad , M. A. El-Dosuky

Scientists have demonstrated that quantum computing has presented novel approaches to address computational challenges, each varying in complexity. Adapting problem-solving strategies is crucial to harness the full potential of quantum…

Computational Complexity · Computer Science 2024-09-13 Arash Vaezi , Ali Movaghar , Mohammad Ghodsi , Seyed Mohammad Hussein Kazemi , Negin Bagheri Noghrehy , Seyed Mohsen Kazemi

Quantum information science explores the frontier of highly complex quantum states, the "entanglement frontier." This study is motivated by the observation (widely believed but unproven) that classical systems cannot simulate highly…

Quantum Physics · Physics 2012-11-13 John Preskill

Efficiently simulating quantum circuits on classical computers is a fundamental challenge in quantum computing. This paper presents a novel theoretical approach that achieves substantial speedups over existing simulators for a wide class of…

Quantum Physics · Physics 2026-02-10 Daksh Shami

Quantum computers hold promise for solving problems intractable for classical computers, especially those with high time or space complexity. Practical quantum advantage can be said to exist for such problems when the end-to-end time for…

Quantum Physics · Physics 2025-09-22 Parikshit Pareek , Abhijith Jayakumar , Carleton Coffrin , Sidhant Misra

This study introduces a hybrid quantum-classical dispatching framework designed for power systems with high renewable penetration. The proposed method integrates a variational quantum algorithm with classical optimization to provide…

Quantum Physics · Physics 2026-01-27 Fu Zhang , Yuming Zhao

This paper proposed a framework based on quantum computing for reliability assessment of complex systems. The 'Quantum Twin' concept was also proposed. The framework can be used to accelerate the reliability assessment of large-scale…

Systems and Control · Electrical Eng. & Systems 2021-04-07 Shutang You

Traditional simulations on High-Performance Computing (HPC) systems typically involve modeling very large domains and/or very complex equations. HPC systems allow running large models, but limits in performance increase that have become…

Integrating quantum mechanics into drug discovery marks a decisive shift from empirical trial-and-error toward quantitative precision. However, the prohibitive cost of ab initio molecular dynamics has historically forced a compromise…

Quantum computing provides a new way for approaching problem solving, enabling efficient solutions for problems that are hard on classical computers. It is based on leveraging how quantum particles behave. With researchers around the world…

Quantum Physics · Physics 2021-09-29 Ahmed Shokry , Moustafa Youssef

Integrating Large Language Models (LLMs) with quantum computing is a critical challenge, hindered by the severe constraints of Noisy Intermediate-Scale Quantum (NISQ) devices, including barren plateaus and limited coherence. Current…

Quantum Physics · Physics 2025-08-12 Yi Pan , Hanqi Jiang , Junhao Chen , Yiwei Li , Huaqin Zhao , Lin Zhao , Yohannes Abate , Yingfeng Wang , Tianming Liu

High Performance Computing (HPC), Artificial Intelligence (AI)/Machine Learning (ML), and Quantum Computing (QC) and communications offer immense opportunities for innovation and impact on society. Researchers in these areas depend on…

Computers and Society · Computer Science 2020-12-18 William Gropp , Sujata Banerjee , Ian Foster