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Enzyme mining is rapidly evolving as a data-driven strategy to identify biocatalysts with tailored functions from the vast landscape of uncharacterized proteins. The integration of machine learning into these workflows enables…

Biomolecules · Quantitative Biology 2025-07-11 Yanzi Zhang , Felix Moorhoff , Sizhe Qiu , Wenjuan Dong , David Medina-Ortiz , Jing Zhao , Mehdi D. Davari

Thermodynamics is fundamental for understanding and synthesizing multi-component materials, while efficient and accurate prediction of it still remain urgent and challenging. As a demonstration of the "Divide and conquer" strategy…

Materials Science · Physics 2020-10-28 Pin-Wen Guan , Venkatasubramanian Viswanathan

Computational drug discovery provides an efficient tool helping large scale lead molecules screening. One of the major tasks of lead discovery is identifying molecules with promising binding affinities towards a target, a protein in…

Biological Physics · Physics 2019-09-18 Liangzhen Zheng , Jingrong Fan , Yuguang Mu

Recent advances in high-throughput genomic technologies coupled with exponential increases in computer processing and memory have allowed us to interrogate the complex aberrant molecular underpinnings of human disease from a genome-wide…

Purpose: Accurate electronic stopping power data is crucial for calculating radiation-induced effects in various applications, from dosimetry and radiotherapy to particle physics. In this study, Stacking Ensemble Machine Learning (EML)…

A key step in interpreting gas-phase ion mobility coupled with mass spectrometry (IM-MS) data for unknown structure prediction involves identifying the most favorable protonated structure. In the gas phase, the site of protonation is…

Machine Learning · Computer Science 2024-11-28 Hongni Jin , Kenneth M. Merz

Nuclear masses are predicted with the Bayesian neural networks by learning the mass surface of even-even nuclei and the correlation energies to their neighbouring nuclei. By keeping the known physics in various sophisticated mass models and…

Nuclear Theory · Physics 2022-08-10 Z. M. Niu , H. Z. Liang

While deeper and wider neural networks are actively pushing the performance limits of various computer vision and machine learning tasks, they often require large sets of labeled data for effective training and suffer from extremely high…

Computer Vision and Pattern Recognition · Computer Science 2017-10-27 Zhi Zhang , Guanghan Ning , Zhihai He

Modern machine learning (ML) systems excel in recognising and classifying images with remarkable accuracy. However, like many computer software systems, they can fail by generating confusing or erroneous outputs or by deferring to human…

Machine Learning · Computer Science 2024-12-12 Milan Maksimovic , Ivan S. Maksymov

The accurate and precise extraction of information from a modern particle physics detector, such as an electromagnetic calorimeter, may be complicated and challenging. In order to overcome the difficulties we propose processing the detector…

Data Analysis, Statistics and Probability · Physics 2022-02-04 Elihu Sela , Shan Huang , David Horn

Two-dimensional electronic spectroscopy has become one of the main experimental tools for analyzing the dynamics of excitonic energy transfer in large molecular complexes. Simplified theoretical models are usually employed to extract model…

Chemical Physics · Physics 2019-01-17 Mirta Rodríguez , Tobias Kramer

Prediction of molecular properties, including physico-chemical properties, is a challenging task in chemistry. Herein we present a new state-of-the-art multitask prediction method based on existing graph neural network models. We have used…

Machine Learning · Computer Science 2019-10-31 Fabio Capela , Vincent Nouchi , Ruud Van Deursen , Igor V. Tetko , Guillaume Godin

We present a proof of concept that machine learning techniques can be used to predict the properties of CNOHF energetic molecules from their molecular structures. We focus on a small but diverse dataset consisting of 109 molecular…

Materials Science · Physics 2018-06-14 Daniel C. Elton , Zois Boukouvalas , Mark S. Butrico , Mark D. Fuge , Peter W. Chung

Machine Learning (ML) techniques have been employed for the high energy physics (HEP) community since the early 80s to deal with a broad spectrum of problems. This work explores the prospects of using Deep Learning techniques to estimate…

High Energy Physics - Phenomenology · Physics 2022-06-22 Neelkamal Mallick , Suraj Prasad , Aditya Nath Mishra , Raghunath Sahoo , Gergely Gábor Barnaföldi

(Abridged) Electron-molecule interaction is a fundamental process in radiation-driven chemistry in space, from the interstellar medium to comets. Therefore, knowledge of interaction cross-sections is key. While there has been a plethora of…

We develop a neural network model, based on the processes of high-energy heavy-ion collisions, to study and predict several experimental observables in Au+Au collisions. We present a data-driven deep learning framework for predicting…

Nuclear Theory · Physics 2026-01-06 Jun-Qi Tao , Xiang Fan , Yang Liu , Yu Sha , Kai Zhou , Hua Zheng , Ben-Wei Zhang

Known for their ability to identify hidden patterns in data, artificial neural networks are among the most powerful machine learning tools. Most notably, neural networks have played a central role in identifying states of matter and phase…

Disordered Systems and Neural Networks · Physics 2020-09-15 Chao Fang , Amin Barzegar , Helmut G. Katzgraber

Predicting materials properties from composition or structure is of great interest to the materials science community. Deep learning has recently garnered considerable interest in materials predictive tasks with low model errors when…

Materials Science · Physics 2021-11-01 Chi Chen , Shyue Ping Ong

Based on an analysis of the short range chemical environment of each atom in a system, standard machine learning based approaches to the construction of interatomic potentials aim at determining directly the central quantity which is the…

Materials Science · Physics 2015-08-05 S. Alireza Ghasemi , Albert Hofstetter , Santanu Saha , Stefan Goedecker

Recently, neural networks have found many applications in different fields including Genetics, Pharmacy, Astrophysics and High Energy Physics [1-3]. In the field of accelerator physics it has been used for control systems [4]. In this paper…

Accelerator Physics · Physics 2018-07-31 N. Joshi , O. Meusel , H. Podlech