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While nowadays deep neural networks achieve impressive performances on semantic segmentation tasks, they are usually trained by optimizing pixel-wise losses such as cross-entropy. As a result, the predictions outputted by such networks…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Yifu Chen , Arnaud Dapogny , Matthieu Cord

Recommending items to users has long been a fundamental task, and studies have tried to improve it ever since. Most well-known models commonly employ representation learning to map users and items into a unified embedding space for matching…

Information Retrieval · Computer Science 2025-04-16 Radin Cheraghi , Amir Mohammad Mahfoozi , Sepehr Zolfaghari , Mohammadshayan Shabani , Maryam Ramezani , Hamid R. Rabiee

Within this paper, the exploration of an evolutionary approach to an alternative CellLineNet: a convolutional neural network adept at the classification of epithelial breast cancer cell lines, is presented. This evolutionary algorithm…

Neural and Evolutionary Computing · Computer Science 2020-07-28 Akwarandu Ugo Nwachuku , Xavier Lewis-Palmer , Darlington Ahiale Akogo

Cell individualization has a vital role in digital pathology image analysis. Deep Learning is considered as an efficient tool for instance segmentation tasks, including cell individualization. However, the precision of the Deep Learning…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Huaqian Wu , Nicolas Souedet , Zhenzhen You , Caroline Jan , Cédric Clouchoux , Thierry Delzescaux

Although current semi-supervised medical segmentation methods can achieve decent performance, they are still affected by the uncertainty in unlabeled data and model predictions, and there is currently a lack of effective strategies that can…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yuanpeng He

In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…

Machine Learning · Computer Science 2022-04-05 Pedro Sandoval-Segura , Wallace Lawson

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

Machine Learning · Computer Science 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…

We present a novel hierarchical triplet loss (HTL) capable of automatically collecting informative training samples (triplets) via a defined hierarchical tree that encodes global context information. This allows us to cope with the main…

Computer Vision and Pattern Recognition · Computer Science 2018-10-17 Weifeng Ge , Weilin Huang , Dengke Dong , Matthew R. Scott

Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…

Machine Learning · Computer Science 2024-08-20 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Cuncong Zhong , Zijun Yao

We propose a novel loss function that dynamically rescales the cross entropy based on prediction difficulty regarding a sample. Deep neural network architectures in image classification tasks struggle to disambiguate visually similar…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Serim Ryou , Seong-Gyun Jeong , Pietro Perona

The antinuclear antibody detection with human epithelial cells is a popular approach for autoimmune diseases diagnosis. The manual evaluation demands time, effort and capital, and automation in screening can greatly aid the physicians in…

Computer Vision and Pattern Recognition · Computer Science 2018-10-31 Vibha Gupta , Arnav Bhavsar

Cell counting in biomedical imaging is pivotal for various clinical applications, yet the interpretability of deep learning models in this domain remains a significant challenge. We propose a novel prototype-based method for interpretable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdurahman Ali Mohammed , Wallapak Tavanapong , Catherine Fonder , Donald S. Sakaguchi

The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through…

Populations and Evolution · Quantitative Biology 2015-05-11 Connor O. McCoy , Trevor Bedford , Vladimir N. Minin , Philip Bradley , Harlan Robins , Frederick A. Matsen

Accurate polyp detection is critical for early colorectal cancer diagnosis. Although remarkable progress has been achieved in recent years, the complex colon environment and concealed polyps with unclear boundaries still pose severe…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Yuncheng Jiang , Zixun Zhang , Yiwen Hu , Guanbin Li , Xiang Wan , Song Wu , Shuguang Cui , Silin Huang , Zhen Li

How a single fertilized cell gives rise to a complex array of specialized cell types in development is a central question in biology. The cells grow, divide, and acquire differentiated characteristics through poorly understood molecular…

Machine Learning · Computer Science 2025-03-26 Da Kuang , Guanwen Qiu , Junhyong Kim

Genome-wide eQTL mapping explores the relationship between gene expression values and DNA variants to understand genetic causes of human disease. Due to the large number of genes and DNA variants that need to be assessed simultaneously,…

Applications · Statistics 2018-04-10 Jacob Rhyne , Jung-Ying Tzeng , Teng Zhang , X. Jessie Jeng

Continual learning aims to acquire new tasks while preserving performance on previously learned ones, but most methods struggle with catastrophic forgetting. Existing approaches typically treat all layers uniformly, often trading stability…

Machine Learning · Computer Science 2025-12-29 Hengyi Wu , Zhenyi Wang , Heng Huang

Deep neural networks have been shown to be very powerful methods for many supervised learning tasks. However, they can also easily overfit to training set biases, i.e., label noise and class imbalance. While both learning with noisy labels…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Tong Wei , Jiang-Xin Shi , Yu-Feng Li , Min-Ling Zhang

Accurately predicting immunotherapy response in Non-Small Cell Lung Cancer (NSCLC) remains a critical unmet need. Existing radiomics and deep learning-based predictive models rely primarily on pre-treatment imaging to predict categorical…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Moinak Bhattacharya , Judy Huang , Amna F. Sher , Gagandeep Singh , Chao Chen , Prateek Prasanna