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While nowadays deep neural networks achieve impressive performances on semantic segmentation tasks, they are usually trained by optimizing pixel-wise losses such as cross-entropy. As a result, the predictions outputted by such networks…
Recommending items to users has long been a fundamental task, and studies have tried to improve it ever since. Most well-known models commonly employ representation learning to map users and items into a unified embedding space for matching…
Within this paper, the exploration of an evolutionary approach to an alternative CellLineNet: a convolutional neural network adept at the classification of epithelial breast cancer cell lines, is presented. This evolutionary algorithm…
Cell individualization has a vital role in digital pathology image analysis. Deep Learning is considered as an efficient tool for instance segmentation tasks, including cell individualization. However, the precision of the Deep Learning…
Although current semi-supervised medical segmentation methods can achieve decent performance, they are still affected by the uncertainty in unlabeled data and model predictions, and there is currently a lack of effective strategies that can…
In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…
Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…
Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…
We present a novel hierarchical triplet loss (HTL) capable of automatically collecting informative training samples (triplets) via a defined hierarchical tree that encodes global context information. This allows us to cope with the main…
Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…
We propose a novel loss function that dynamically rescales the cross entropy based on prediction difficulty regarding a sample. Deep neural network architectures in image classification tasks struggle to disambiguate visually similar…
The antinuclear antibody detection with human epithelial cells is a popular approach for autoimmune diseases diagnosis. The manual evaluation demands time, effort and capital, and automation in screening can greatly aid the physicians in…
Cell counting in biomedical imaging is pivotal for various clinical applications, yet the interpretability of deep learning models in this domain remains a significant challenge. We propose a novel prototype-based method for interpretable…
The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through…
Accurate polyp detection is critical for early colorectal cancer diagnosis. Although remarkable progress has been achieved in recent years, the complex colon environment and concealed polyps with unclear boundaries still pose severe…
How a single fertilized cell gives rise to a complex array of specialized cell types in development is a central question in biology. The cells grow, divide, and acquire differentiated characteristics through poorly understood molecular…
Genome-wide eQTL mapping explores the relationship between gene expression values and DNA variants to understand genetic causes of human disease. Due to the large number of genes and DNA variants that need to be assessed simultaneously,…
Continual learning aims to acquire new tasks while preserving performance on previously learned ones, but most methods struggle with catastrophic forgetting. Existing approaches typically treat all layers uniformly, often trading stability…
Deep neural networks have been shown to be very powerful methods for many supervised learning tasks. However, they can also easily overfit to training set biases, i.e., label noise and class imbalance. While both learning with noisy labels…
Accurately predicting immunotherapy response in Non-Small Cell Lung Cancer (NSCLC) remains a critical unmet need. Existing radiomics and deep learning-based predictive models rely primarily on pre-treatment imaging to predict categorical…