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Deep neural networks have achieved remarkable performance in various text-based tasks but often lack interpretability, making them less suitable for applications where transparency is critical. To address this, we propose ProtoLens, a novel…

Computation and Language · Computer Science 2024-10-25 Bowen Wei , Ziwei Zhu

Machine learning classification systems are susceptible to poor performance when trained with incorrect ground truth labels, even when data is well-curated by expert annotators. As machine learning becomes more widespread, it is…

Machine Learning · Computer Science 2026-01-16 Zan Chaudhry , Noam H. Rotenberg , Brian Caffo , Craig K. Jones , Haris I. Sair

Numerical interactions leading to users sharing textual content published by others are naturally represented by a network where the individuals are associated with the nodes and the exchanged texts with the edges. To understand those…

Machine Learning · Computer Science 2024-02-14 Rémi Boutin , Pierre Latouche , Charles Bouveyron

The recognition of multi-class cell nuclei can significantly facilitate the process of histopathological diagnosis. Numerous pathological datasets are currently available, but their annotations are inconsistent. Most existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Junjia Huang , Haofeng Li , Xiang Wan , Guanbin Li

We introduce Ibex, a pan-immunoglobulin structure prediction model that achieves state-of-the-art accuracy in modeling the variable domains of antibodies, nanobodies, and T-cell receptors. Unlike previous approaches, Ibex explicitly…

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Dermatological diseases are among the most common disorders worldwide. This paper presents the first study of the interpretability and imbalanced semi-supervised learning of the multiclass intelligent skin diagnosis framework (ISDL) using…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Futian Weng , Yuanting Ma , Jinghan Sun , Shijun Shan , Qiyuan Li , Jianping Zhu , Yang Wang , Yan Xu

Recently, deep learning-based methods achieved promising performance in nuclei detection and classification applications. However, training deep learning-based methods requires a large amount of pixel-wise annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Nazanin Moradinasab , Rebecca A. Deaton , Laura S. Shankman , Gary K. Owens , Donald E. Brown

Metaproteomics are becoming widely used in microbiome research for gaining insights into the functional state of the microbial community. Current metaproteomics studies are generally based on high-throughput tandem mass spectrometry (MS/MS)…

Quantitative Methods · Quantitative Biology 2020-09-24 Xuan Guo , Shichao Feng

Antibodies are widely used in life-sciences and medical therapy. Yet, broadly applicable methods are missing to determine, in the biological system of choice, antibody specificity and its quantitative contribution to e.g. immunofluorescence…

Quantitative Methods · Quantitative Biology 2024-07-09 Dominik Tschimmel , Momina Saeed , Maria Milani , Steffen Waldherr , Tim Hucho

Uncertainty estimation is critical for cost-sensitive deep-learning applications (i.e. disease diagnosis). It is very challenging partly due to the inaccessibility of uncertainty groundtruth in most datasets. Previous works proposed to…

Machine Learning · Computer Science 2021-10-18 Bolian Li , Zige Zheng , Changqing Zhang

The Epithelial Dysplasia (ED) is a tissue alteration commonly present in lesions preceding oral cancer, being its presence one of the most important factors in the progression toward carcinoma. This study proposes a method to design a low…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Karoline da Rocha , José C. M. Bermudez , Elena R. C. Rivero , Márcio H. Costa

Early warning for epilepsy patients is crucial for their safety and well-being, in particular to prevent or minimize the severity of seizures. Through the patients' EEG data, we propose a meta learning framework to improve the prediction of…

Machine Learning · Computer Science 2024-01-12 Peng Zhang , Ting Gao , Jin Guo , Jinqiao Duan , Sergey Nikolenko

Prototype-based neural networks offer interpretable predictions by comparing inputs to learned, representative signal patterns anchored in training data. While such models have shown promise in the classification of physiological data, it…

Machine Learning · Computer Science 2026-05-28 Sahil Sethi , David Chen , Michael C. Burkhart , Nipun Bhandari , Bashar Ramadan , Brett Beaulieu-Jones

Lack of enough labeled data is a major problem in building machine learning based models when the manual annotation (labeling) is error-prone, expensive, tedious, and time-consuming. In this paper, we introduce an iterative deep learning…

Computer Vision and Pattern Recognition · Computer Science 2019-01-15 Saeed S. Alahmari , Dmitry Goldgof , Lawrence O. Hall , Palak Dave , Hady Ahmady Phoulady , Peter R. Mouton

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

In this paper we present a system for the detection of immunogold particles and a Transfer Learning (TL) framework for the recognition of these immunogold particles. Immunogold particles are part of a high-magnification method for the…

The use of deep learning (DL) in medical image analysis has significantly improved the ability to predict lung cancer. In this study, we introduce a novel deep convolutional neural network (CNN) model, named ResNet+, which is based on the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Ahmad Chaddad , Jihao Peng , Yihang Wu

Deep neural networks perform well on classification tasks where data streams are i.i.d. and labeled data is abundant. Challenges emerge with non-stationary training data streams such as continual learning. One powerful approach that has…

To interpret the genetic profile present in a patient sample, it is necessary to know which mutations have important roles in the development of the corresponding cancer type. Named entity recognition is a core step in the text mining…

Computation and Language · Computer Science 2021-06-16 Jiarun Cao , Elke M van Veen , Niels Peek , Andrew G Renehan , Sophia Ananiadou
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