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Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

Image and Video Processing · Electrical Eng. & Systems 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

Massive sized survival datasets are becoming increasingly prevalent with the development of the healthcare industry. Such datasets pose computational challenges unprecedented in traditional survival analysis use-cases. A popular way for…

Methodology · Statistics 2023-05-09 Nir Keret , Malka Gorfine

Many diseases are considered to be closely related to the changes in the gut microbial community, including colorectal cancer (CRC), which is one of the most common cancers in the world. The diagnostic classification and etiological…

Quantitative Methods · Quantitative Biology 2023-10-19 Shan Tang , Shanjun Mao , Yangyang Chen , Falong Tan , Lihua Duan , Cong Pian , Xiangxiang Zeng

Heart failure (HF) is a critical condition in which the accurate prediction of mortality plays a vital role in guiding patient management decisions. However, clinical datasets used for mortality prediction in HF often suffer from an…

Machine Learning · Computer Science 2024-05-29 Hanif Kia , Mansour Vali , Hadi Sabahi

Background: Effective allocation of limited donor lungs in cystic fibrosis (CF) requires accurate survival predictions, so that high-risk patients may be prioritized for transplantation. In practice, decisions about allocation are made…

Applications · Statistics 2017-06-30 Aasthaa Bansal , Nicole Mayer-Hamblett , Christopher H. Goss , Patrick J. Heagerty

Despite the fact that cancer survivability rates vary greatly between stages, traditional survival prediction models have frequently been trained and assessed using examples from all combined phases of the disease. This method may result in…

Machine Learning · Computer Science 2026-01-08 Parisa Poorhasani , Bogdan Iancu

Survival outcome assessment is challenging and inherently associated with multiple clinical factors (e.g., imaging and genomics biomarkers) in cancer. Enabling multimodal analytics promises to reveal novel predictive patterns of patient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Kexin Ding , Mu Zhou , Dimitris N. Metaxas , Shaoting Zhang

This thesis develops computational methods in similarity-preserving hashing, classification, and cancer genomics. Standard space partitioning-based hashing relies on Binary Search Trees (BSTs), but their exponential growth and sparsity…

Machine Learning · Computer Science 2025-08-26 Prashant Gupta

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Colorectal cancer (CRC) is among the top three malignant tumor types in terms of morbidity and mortality. Histopathological images are the gold standard for diagnosing colon cancer. Cellular nuclei instance segmentation and classification,…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Liangrui Pan , Lian Wang , Zhichao Feng , Zhujun Xu , Liwen Xu , Shaoliang Peng

We develop a neural network model to classify liver cancer patients into high-risk and low-risk groups using genomic data. Our approach provides a novel technique to classify big data sets using neural network models. We preprocess the data…

Machine Learning · Statistics 2016-11-28 Ashkan Zeinalzadeh , Tom Wenska , Gordon Okimoto

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

Methodology · Statistics 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs

Prediction of Overall Survival (OS) of brain cancer patients from multi-modal MRI is a challenging field of research. Most of the existing literature on survival prediction is based on Radiomic features, which does not consider either…

Quantitative Methods · Quantitative Biology 2021-09-08 Subhashis Banerjee , Sushmita Mitra , Lawrence O. Hall

Cerebral stroke, the second most substantial cause of death universally, has been a primary public health concern over the last few years. With the help of machine learning techniques, early detection of various stroke alerts is accessible,…

Machine Learning · Computer Science 2022-11-16 Yuru Jing

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

Quantitative Methods · Quantitative Biology 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Brain tumor is one of the most high-risk cancers which causes the 5-year survival rate of only about 36%. Accurate diagnosis of brain tumor is critical for the treatment planning. However, complete data are not always available in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-05-28 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

In this paper, we use partially rank-ordered set (PROS) sampling design with multiple concomitants in a breast cancer study and propose a method to estimate the proportion of patients with malignant (cancerous) breast tumours in a given…

Methodology · Statistics 2014-11-11 Armin Hatefi , Mohammad Jafari Jozani

Patients with metastatic breast cancer (mBC) undergo repeated computed tomography (CT) imaging during treatment to monitor disease progression. Accurate longitudinal tracking of individual lesions across scans from multiple radiologists is…

Non-parametric maximum likelihood estimation encompasses a group of classic methods to estimate distribution-associated functions from potentially censored and truncated data, with extensive applications in survival analysis. These methods,…

Methodology · Statistics 2021-08-05 Justin D. Tubbs , Lane Guolan Chen , Thuan Quoc Thach , Pak C. Sham

In this study, we present a hybrid CNN-RNN approach to investigate long-term survival of subjects in a lung cancer screening study. Subjects who died of cardiovascular and respiratory causes were identified whereby the CNN model was used to…

Machine Learning · Computer Science 2023-03-21 Yaozhi Lu , Shahab Aslani , An Zhao , Ahmed Shahin , David Barber , Mark Emberton , Daniel C. Alexander , Joseph Jacob