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Diffusion and Poisson flow models have shown impressive performance in a wide range of generative tasks, including low-dose CT image denoising. However, one limitation in general, and for clinical applications in particular, is slow…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Dennis Hein , Staffan Holmin , Timothy Szczykutowicz , Jonathan S Maltz , Mats Danielsson , Ge Wang , Mats Persson

X-ray computed tomography (CT) is widely used for medical diagnosis and treatment planning; however, concerns about ionizing radiation exposure drive efforts to optimize image quality at lower doses. This study introduces Poisson Flow…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Dennis Hein , Grant Stevens , Adam Wang , Ge Wang

The Poisson Flow Consistency Model (PFCM) is a consistency-style model based on the robust Poisson Flow Generative Model++ (PFGM++) which has achieved success in unconditional image generation and CT image denoising. Yet the PFCM can only…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Anthony Zhang , Mahmut Gokmen , Dennis Hein , Rongjun Ge , Wenjun Xia , Ge Wang , Jin Chen

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman

Sparse-view computed tomography (CT) is a practical solution to reduce radiation dose, but the resulting ill-posed inverse problem poses significant challenges for accurate image reconstruction. Although deep learning and diffusion-based…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Changsheng Fang , Yongtong Liu , Bahareh Morovati , Shuo Han , Yu Shi , Li Zhou , Shuyi Fan , Hengyong Yu

Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Computed tomography (CT) is a major medical imaging modality. Clinical CT scenarios, such as low-dose screening, sparse-view scanning, and metal implants, often lead to severe noise and artifacts in reconstructed images, requiring improved…

Image and Video Processing · Electrical Eng. & Systems 2025-06-04 Wenjun Xia , Chuang Niu , Ge Wang

In supervised learning for image denoising, usually the paired clean images and noisy images are collected or synthesised to train a denoising model. L2 norm loss or other distance functions are used as the objective function for training.…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Yutong Xie , Minne Yuan , Bin Dong , Quanzheng Li

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

In clinical practice, multiphase contrast-enhanced CT (MCCT) is important for physiological and pathological imaging with contrast injection, which undergoes non-contrast, venous, and delayed phases. Inevitably, the accumulated radiation…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Rongjun Ge , Ge Wang

Diffusion models have significant impact on wide range of generative tasks, especially on image inpainting and restoration. Although the improvements on aiming for decreasing number of function evaluations (NFE), the iterative results are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Mahmut S. Gokmen , Jie Zhang , Ge Wang , Jin Chen , Cody Bumgardner

Diffusion models have demonstrated remarkable efficacy in generating high-quality samples. Existing diffusion-based image restoration algorithms exploit pre-trained diffusion models to leverage data priors, yet they still preserve elements…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Hongjie Wu , Linchao He , Mingqin Zhang , Dongdong Chen , Kunming Luo , Mengting Luo , Ji-Zhe Zhou , Hu Chen , Jiancheng Lv

Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Runyi Li

In computed tomography (CT), reducing the number of projection views is an effective strategy to lower radiation exposure and/or improve temporal resolution. However, this often results in severe aliasing artifacts and loss of structural…

Image and Video Processing · Electrical Eng. & Systems 2025-11-19 Changsheng Fang , Yongtong Liu , Bahareh Morovati , Shuo Han , Li Zhou , Hengyong Yu

Image-generative artificial intelligence (AI) has garnered significant attention in recent years. In particular, the diffusion model, a core component of generative AI, produces high-quality images with rich diversity. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Sho Ozaki , Shizuo Kaji , Toshikazu Imae , Kanabu Nawa , Hideomi Yamashita , Keiichi Nakagawa

Large denoising diffusion models, such as Stable Diffusion, have been trained on billions of image-caption pairs to perform text-conditioned image generation. As a byproduct of this training, these models have acquired general knowledge…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Alexandros Graikos , Nebojsa Jojic , Dimitris Samaras

The reconstruction of X-rays CT images from sparse or limited-angle geometries is a highly challenging task. The lack of data typically results in artifacts in the reconstructed image and may even lead to object distortions. For this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Davide Evangelista , Pasquale Cascarano , Elena Loli Piccolomini

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Diffusion-based Deep Generative Models (DDGMs) offer state-of-the-art performance in generative modeling. Their main strength comes from their unique setup in which a model (the backward diffusion process) is trained to reverse the forward…

Machine Learning · Computer Science 2022-06-02 Kamil Deja , Anna Kuzina , Tomasz Trzciński , Jakub M. Tomczak
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