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Related papers: DCAlign v1.0: Aligning biological sequences using …

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For unsupervised domain adaptation (UDA), to alleviate the effect of domain shift, many approaches align the source and target domains in the feature space by adversarial learning or by explicitly aligning their statistics. However, the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Guoqiang Wei , Cuiling Lan , Wenjun Zeng , Zhibo Chen

Continual learning is a process that involves training learning agents to sequentially master a stream of tasks or classes without revisiting past data. The challenge lies in leveraging previously acquired knowledge to learn new tasks…

Machine Learning · Computer Science 2024-02-21 Marcus de Carvalho , Mahardhika Pratama , Jie Zhang , Chua Haoyan , Edward Yapp

We introduce a new family of neural network models called Convolutional Dynamic Alignment Networks (CoDA-Nets), which are performant classifiers with a high degree of inherent interpretability. Their core building blocks are Dynamic…

Machine Learning · Computer Science 2024-01-17 Moritz Böhle , Mario Fritz , Bernt Schiele

Recent studies have demonstrated significant progress in aligning text-to-image diffusion models with human preference via Reinforcement Learning from Human Feedback. However, while existing methods achieve high scores on automated reward…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Chubin Chen , Sujie Hu , Jiashu Zhu , Meiqi Wu , Jintao Chen , Yanxun Li , Nisha Huang , Chengyu Fang , Jiahong Wu , Xiangxiang Chu , Xiu Li

Large language models (LLMs) exhibit remarkable capabilities across diverse tasks, yet aligning them efficiently and effectively with human expectations remains a critical challenge. This thesis advances LLM alignment by introducing novel…

Computation and Language · Computer Science 2025-06-12 Yuxin Jiang

Distortion identification and rectification in images and videos is vital for achieving good performance in downstream vision applications. Instead of relying on fixed trial-and-error based image processing pipelines, we propose a two-level…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Aditya Kapoor , Harshad Khadilkar , Jayvardhana Gubbi

Conversational Query Reformulation (CQR) has significantly advanced in addressing the challenges of conversational search, particularly those stemming from the latent user intent and the need for historical context. Recent works aimed to…

Computation and Language · Computer Science 2025-01-06 Yilong Lai , Jialong Wu , Congzhi Zhang , Haowen Sun , Deyu Zhou

Disentangled generative models map a latent code vector to a target space, while enforcing that a subset of the learned latent codes are interpretable and associated with distinct properties of the target distribution. Recent advances have…

Machine Learning · Computer Science 2020-08-10 Zinan Lin , Kiran Koshy Thekumparampil , Giulia Fanti , Sewoong Oh

Calibrating mathematical models of biological processes is essential for achieving predictive accuracy and gaining mechanistic insight. However, this task remains challenging due to limited and noisy data, significant biological…

Quantitative Methods · Quantitative Biology 2025-12-04 Piotr Gwiazda , Alexey Kazarnikov , Anna Marciniak-Czochra , Zuzanna Szymańska

Alignment-based sequence similarity searches, while accurate for some type of sequences, can produce incorrect results when used on more divergent but functionally related sequences that have undergone the sequence rearrangements observed…

Genomics · Quantitative Biology 2015-01-21 Ivan Borozan , Stuart Watt , Vincent Ferretti

Recently developed technologies to generate single-cell genomic data have made a revolutionary impact in the field of biology. Multi-omics assays offer even greater opportunities to understand cellular states and biological processes.…

Genomics · Quantitative Biology 2022-01-19 Stefan Stanojevic , Yijun Li , Lana X. Garmire

Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and interpret the tsunami of metagenomic sequencing data generated by high-throughput sequencing. Compared to alternative (e. g., similarity-based)…

Populations and Evolution · Quantitative Biology 2025-01-09 Lucas Czech , Alexandros Stamatakis , Micah Dunthorn , Pierre Barbera

Recently developed deep learning models are able to learn to segment scenes into component objects without supervision. This opens many new and exciting avenues of research, allowing agents to take objects (or entities) as inputs, rather…

Sequential recommendations have made great strides in accurately predicting the future behavior of users. However, seeking accuracy alone may bring side effects such as unfair and overspecialized recommendation results. In this work, we…

Information Retrieval · Computer Science 2023-09-07 Jiayi Chen , Wen Wu , Liye Shi , Yu Ji , Wenxin Hu , Wei Zheng , Liang He

The success of deep learning (DL) is often achieved with large models and high complexity during both training and post-training inferences, hindering training in resource-limited settings. To alleviate these issues, this paper introduces a…

Machine Learning · Computer Science 2025-01-20 En-hui Yang , Shayan Mohajer Hamidi

Sequence alignments are fundamental to bioinformatics which has resulted in a variety of optimized implementations. Unfortunately, the vast majority of them are hand-tuned and specific to certain architectures and execution models. This not…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-17 André Müller , Bertil Schmidt , Andreas Hildebrandt , Richard Membarth , Roland Leißa , Matthis Kruse , Sebastian Hack

Producing trustworthy and reliable Large Language Models (LLMs) has become increasingly important as their usage becomes more widespread. Calibration seeks to achieve this by improving the alignment between the model's confidence and the…

Computation and Language · Computer Science 2025-12-16 Glenn Zhang , Treasure Mayowa , Jason Fan , Yicheng Fu , Aaron Sandoval , Sean O'Brien , Kevin Zhu

We propose 3D Congealing, a novel problem of 3D-aware alignment for 2D images capturing semantically similar objects. Given a collection of unlabeled Internet images, our goal is to associate the shared semantic parts from the inputs and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Yunzhi Zhang , Zizhang Li , Amit Raj , Andreas Engelhardt , Yuanzhen Li , Tingbo Hou , Jiajun Wu , Varun Jampani

Alignment of large language models (LLMs) involves training models on preference-contrastive output pairs to adjust their responses according to human preferences. To obtain such contrastive pairs, traditional methods like RLHF and RLAIF…

Computation and Language · Computer Science 2024-10-18 Zekun Moore Wang , Shawn Wang , Kang Zhu , Jiaheng Liu , Ke Xu , Jie Fu , Wangchunshu Zhou , Wenhao Huang

We propose a new method for computing Dynamic Mode Decomposition (DMD) evolution matrices, which we use to analyze dynamical systems. Unlike the majority of existing methods, our approach is based on a variational formulation consisting of…

Numerical Analysis · Mathematics 2019-05-24 Omri Azencot , Wotao Yin , Andrea Bertozzi