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Related papers: DCAlign v1.0: Aligning biological sequences using …

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Cross-modal alignment aims to map heterogeneous modalities into a shared latent space, as exemplified by models like CLIP, which benefit from large-scale image-text pretraining for strong recognition capabilities. However, when operating in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Jiaxiang Liu , Yuan Wang , Jiawei Du , Joey Tianyi Zhou , Mingkun Xu , Zuozhu Liu

The quality of finetuning data is crucial for aligning large language models (LLMs) with human values. Current methods to improve data quality are either labor-intensive or prone to factual errors caused by LLM hallucinations. This paper…

Computation and Language · Computer Science 2024-04-18 Run-Ze Fan , Xuefeng Li , Haoyang Zou , Junlong Li , Shwai He , Ethan Chern , Jiewen Hu , Pengfei Liu

Integration of multi-omics data provides opportunities for revealing biological mechanisms related to certain phenotypes. We propose a novel method of multi-omics integration called supervised deep generalized canonical correlation analysis…

Quantitative Methods · Quantitative Biology 2022-04-21 Jeongyoung Hwang , Sehwan Moon , Hyunju Lee

In-context image generation and editing (ICGE) enables users to specify visual concepts through interleaved image-text prompts, demanding precise understanding and faithful execution of user intent. Although recent unified multimodal models…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Runze He , Yiji Cheng , Tiankai Hang , Zhimin Li , Yu Xu , Zijin Yin , Shiyi Zhang , Wenxun Dai , Penghui Du , Ao Ma , Chunyu Wang , Qinglin Lu , Jizhong Han , Jiao Dai

The subject of this paper is to study conformance checking for timed models, that is, process models that consider both the sequence of events in a process as well as the timestamps at which each event is recorded. Time-aware process mining…

Formal Languages and Automata Theory · Computer Science 2022-07-06 Thomas Chatain , Neha Rino

Extracting meaningful latent representations from high-dimensional sequential data is a crucial challenge in machine learning, with applications spanning natural science and engineering. We introduce InfoDPCCA, a dynamic probabilistic…

Machine Learning · Computer Science 2025-06-11 Shiqin Tang , Shujian Yu

Darwin is a genomics co-processor that achieved a 15000x acceleration on long read assembly through innovative hardware and algorithm co-design. Darwins algorithms and hardware implementation were specifically designed for DNA analysis…

Quantitative Methods · Quantitative Biology 2019-02-12 Sahand Kashani , Stuart Byma , James R. Larus

Discrimination and calibration represent two important properties of survival analysis, with the former assessing the model's ability to accurately rank subjects and the latter evaluating the alignment of predicted outcomes with actual…

Machine Learning · Computer Science 2024-06-04 Shi-ang Qi , Yakun Yu , Russell Greiner

Data assimilation (DA) aims to estimate the full state of a dynamical system by combining partial and noisy observations with a prior model forecast, commonly referred to as the background. In atmospheric applications, this problem is…

Atmospheric and Oceanic Physics · Physics 2025-05-29 Jing-An Sun , Hang Fan , Junchao Gong , Ben Fei , Kun Chen , Fenghua Ling , Wenlong Zhang , Wanghan Xu , Li Yan , Pierre Gentine , Lei Bai

Diffusion Language Models (DLMs) have recently achieved significant success due to their any-order generation capabilities. However, existing inference methods typically rely on local, immediate-step metrics such as confidence or entropy…

Computation and Language · Computer Science 2025-12-03 Kecheng Chen , Ziru Liu , Xijia Tao , Hui Liu , Xinyu Fu , Suiyun Zhang , Dandan Tu , Lingpeng Kong , Rui Liu , Haoliang Li

Diffusion Language Models (DLMs) offer a promising parallel generation paradigm but suffer from slow inference due to numerous refinement steps and the inability to use standard KV caching. We introduce CDLM (Consistency Diffusion Language…

Machine Learning · Computer Science 2026-02-23 Minseo Kim , Chenfeng Xu , Coleman Hooper , Harman Singh , Ben Athiwaratkun , Ce Zhang , Kurt Keutzer , Amir Gholami

Collaborative 3D object detection exploits information exchange among multiple agents to enhance accuracy of object detection in presence of sensor impairments such as occlusion. However, in practice, pose estimation errors due to imperfect…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Yifan Lu , Quanhao Li , Baoan Liu , Mehrdad Dianati , Chen Feng , Siheng Chen , Yanfeng Wang

Current unified multimodal models for image generation and editing typically rely on massive parameter scales (e.g., >10B), entailing prohibitive training costs and deployment footprints. In this work, we present DeepGen 1.0, a lightweight…

The paper surveys the evolution of main algorithmic techniques to compare and search biological sequences. We highlight key algorithmic ideas emerged in response to several interconnected factors: shifts of biological analytical paradigm,…

Genomics · Quantitative Biology 2018-11-15 Gregory Kucherov

Biological and artificial information processing systems form representations of the world that they can use to categorize, reason, plan, navigate, and make decisions. How can we measure the similarity between the representations formed by…

With distributed computing and mobile applications, synchronizing diverging replicas of data structures is a more and more common problem. We use algebraic methods to reason about filesystem operations, and introduce a simplified definition…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-24 Elod Pal Csirmaz

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

Kernel alignment measures the degree of similarity between two kernels. In this paper, inspired from kernel alignment, we propose a new Linear Discriminant Analysis (LDA) formulation, kernel alignment LDA (kaLDA). We first define two…

Machine Learning · Computer Science 2016-10-17 Shuai Zheng , Chris Ding

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

One of the well-known challenges in computer vision tasks is the visual diversity of images, which could result in an agreement or disagreement between the learned knowledge and the visual content exhibited by the current observation. In…

Machine Learning · Computer Science 2020-01-03 Yan Luo , Yongkang Wong , Mohan S. Kankanhalli , Qi Zhao