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Spatial Transcriptomics (ST) allows a high-resolution measurement of RNA sequence abundance by systematically connecting cell morphology depicted in Hematoxylin and Eosin (H&E) stained histology images to spatially resolved gene…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Sichen Zhu , Yuchen Zhu , Molei Tao , Peng Qiu

Semi-supervised learning (SSL) has emerged as a promising paradigm in medical image segmentation, offering competitive performance while substantially reducing the need for extensive manual annotation. When combined with active learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Yi Yang

Computer-aided diagnosis (CAD) can help pathologists improve diagnostic accuracy together with consistency and repeatability for cancers. However, the CAD models trained with the histopathological images only from a single center (hospital)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Jun Shi , Yuanming Zhang , Zheng Li , Xiangmin Han , Saisai Ding , Jun Wang , Shihui Ying

Unsupervised semantic segmentation aims to discover groupings within and across images that capture object and view-invariance of a category without external supervision. Grouping naturally has levels of granularity, creating ambiguity in…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Tsung-Wei Ke , Jyh-Jing Hwang , Yunhui Guo , Xudong Wang , Stella X. Yu

Despite the success of deep learning based models in medical image segmentation, most state-of-the-art (SOTA) methods perform fully-supervised learning, which commonly rely on large scale annotated training datasets. However, medical image…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Zhendi Gong , Xin Chen

We present Generative Semantic Segmentation (GSS), a generative learning approach for semantic segmentation. Uniquely, we cast semantic segmentation as an image-conditioned mask generation problem. This is achieved by replacing the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Jiaqi Chen , Jiachen Lu , Xiatian Zhu , Li Zhang

Diffusion models have demonstrated excellent performance in image generation. Although various few-shot semantic segmentation (FSS) models with different network structures have been proposed, performance improvement has reached a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Weimin Tan , Siyuan Chen , Bo Yan

Hyperspectral images (HSIs) provide exceptional spatial and spectral resolution of a scene, crucial for various remote sensing applications. However, the high dimensionality, presence of noise and outliers, and the need for precise labels…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Kangning Cui , Ruoning Li , Sam L. Polk , Yinyi Lin , Hongsheng Zhang , James M. Murphy , Robert J. Plemmons , Raymond H. Chan

Recent advances in deep learning have shown that learning robust feature representations is critical for the success of many computer vision tasks, including medical image segmentation. In particular, both transformer and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-03 David Li , Anvar Kurmukov , Mikhail Goncharov , Roman Sokolov , Mikhail Belyaev

Self-supervised representation learning has been highly promising for histopathology image analysis with numerous approaches leveraging their patient-slide-patch hierarchy to learn better representations. In this paper, we explore how the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Hasindri Watawana , Kanchana Ranasinghe , Tariq Mahmood , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

Semi-supervised learning (SSL) can reduce the need for large labelled datasets by incorporating unlabelled data into the training. This is particularly interesting for semantic segmentation, where labelling data is very costly and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Sebastian Scherer , Robin Schön , Rainer Lienhart

Dataset distillation methods have achieved remarkable success in distilling a large dataset into a small set of representative samples. However, they are not designed to produce a distilled dataset that can be effectively used for…

Machine Learning · Computer Science 2024-04-15 Dong Bok Lee , Seanie Lee , Joonho Ko , Kenji Kawaguchi , Juho Lee , Sung Ju Hwang

In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Training deep networks with limited labeled data while achieving a strong generalization ability is key in the quest to reduce human annotation efforts. This is the goal of semi-supervised learning, which exploits more widely available…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Daiqing Li , Junlin Yang , Karsten Kreis , Antonio Torralba , Sanja Fidler

Self-supervised learning (SSL) enables label efficient training for machine learning models. This is essential for domains such as medical imaging, where labels are costly and time-consuming to curate. However, the most effective supervised…

Computer Vision and Pattern Recognition · Computer Science 2023-05-16 Cara Van Uden , Jeremy Irvin , Mars Huang , Nathan Dean , Jason Carr , Andrew Ng , Curtis Langlotz

Medical image segmentation methods are generally designed as fully-supervised to guarantee model performance, which require a significant amount of expert annotated samples that are high-cost and laborious. Semi-supervised image…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Xiangyu Zhao , Zengxin Qi , Sheng Wang , Qian Wang , Xuehai Wu , Ying Mao , Lichi Zhang

In the realm of high-resolution (HR), fine-grained image segmentation, the primary challenge is balancing broad contextual awareness with the precision required for detailed object delineation, capturing intricate details and the finest…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Qian Yu , Peng-Tao Jiang , Hao Zhang , Jinwei Chen , Bo Li , Lihe Zhang , Huchuan Lu

A major limitation in applying deep learning to artificial intelligence (AI) systems is the scarcity of high-quality curated datasets. We investigate strong augmentation based self-supervised learning (SSL) techniques to address this…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 John D. Miller , Vignesh A. Arasu , Albert X. Pu , Laurie R. Margolies , Weiva Sieh , Li Shen

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre
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