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Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Recent years have witnessed remarkable progress made in large language models (LLMs). Such advancements, while garnering significant attention, have concurrently elicited various concerns. The potential of these models is undeniably vast;…

Computation and Language · Computer Science 2023-09-27 Tianhao Shen , Renren Jin , Yufei Huang , Chuang Liu , Weilong Dong , Zishan Guo , Xinwei Wu , Yan Liu , Deyi Xiong

This report analyzes key trends, challenges, risks, and opportunities associated with the development of Large Language Models (LLMs) globally. It examines national experiences in developing LLMs and assesses the feasibility of investment…

Advances in large language models (LLMs) have driven an explosion of interest about their societal impacts. Much of the discourse around how they will impact social equity has been cautionary or negative, focusing on questions like "how…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Large Language Models (LLMs) have emerged as transformative tools in artificial intelligence (AI), exhibiting remarkable capabilities across diverse tasks such as text generation, reasoning, and decision-making. While their success has…

The rapid advancement of Large Language Models (LLMs) is reshaping software engineering by profoundly influencing coding, documentation, and system maintenance practices. As these tools become deeply embedded in developers' daily workflows,…

Software Engineering · Computer Science 2025-12-29 Vítor Mateus de Brito , Kleinner Farias

Personalization of Large Language Models (LLMs) has recently become increasingly important with a wide range of applications. Despite the importance and recent progress, most existing works on personalized LLMs have focused either entirely…

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

The advancement of generative AI, particularly large language models (LLMs), has a significant impact on politics and democracy, offering potential across various domains, including policymaking, political communication, analysis, and…

Computation and Language · Computer Science 2024-12-17 Goshi Aoki

Natural language processing (NLP) has been traditionally applied to medicine, and generative large language models (LLMs) have become prominent recently. However, the differences between them across different medical tasks remain…

Large language models (LLMs) have revolutionized natural language processing with their exceptional understanding, synthesizing, and reasoning capabilities. However, deploying LLMs on resource-constrained edge devices presents significant…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Yue Zheng , Yuhao Chen , Bin Qian , Xiufang Shi , Yuanchao Shu , Jiming Chen

Large Language Models have quickly become a central component of modern software development workflows, and software practitioners are increasingly integrating LLMs into various stages of the software development lifecycle. Despite the…

Software Engineering · Computer Science 2025-10-13 Italo Santos , Cleyton Magalhaes , Ronnie de Souza Santos

Large Language Models (LLMs) are often proposed as tools to streamline clinical documentation, a task viewed as both high-volume and low-risk. However, even seemingly straightforward applications of LLMs raise complex sociotechnical…

Human-Computer Interaction · Computer Science 2025-09-05 Kristina L. Kupferschmidt , Kieran O'Doherty , Joshua A. Skorburg

This comprehensive literature review examines the emerging applications of Large Language Models (LLMs) in power system engineering. Through a systematic analysis of recent research published between 2020 and 2025, we explore how LLMs are…

Systems and Control · Electrical Eng. & Systems 2025-12-16 Muhammad Sarwar , Muhammad Rizwan , Mubushra Aziz , Abdul Rehman Sudais

Large Language Models (LLMs) have become a key topic in AI and NLP, transforming sectors like healthcare, finance, education, and marketing by improving customer service, automating tasks, providing insights, improving diagnostics, and…

Artificial Intelligence · Computer Science 2025-12-05 Vignesh Kumar Kembu , Pierandrea Morandini , Marta Bianca Maria Ranzini , Antonino Nocera

Mental health is increasingly critical in contemporary healthcare, with psychotherapy demanding dynamic, context-sensitive interactions that traditional NLP methods struggle to capture. Large Language Models (LLMs) offer significant…

Computation and Language · Computer Science 2025-06-30 Hongbin Na , Yining Hua , Zimu Wang , Tao Shen , Beibei Yu , Lilin Wang , Wei Wang , John Torous , Ling Chen

Large language models have proliferated across multiple domains in as short period of time. There is however hesitation in the medical and healthcare domain towards their adoption because of issues like factuality, coherence, and…

Computation and Language · Computer Science 2023-11-06 Muhammad Aurangzeb Ahmad , Ilker Yaramis , Taposh Dutta Roy

The integration of Large Language Models (LLMs) into healthcare applications offers promising advancements in medical diagnostics, treatment recommendations, and patient care. However, the susceptibility of LLMs to adversarial attacks poses…

Artificial Intelligence · Computer Science 2024-12-18 Yifan Yang , Qiao Jin , Furong Huang , Zhiyong Lu

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov