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We derive the optimal estimates of the free energies of an arbitrary number of thermodynamic states from nonequilibrium work measurements; the work data are collected from forward and reverse switching processes and obey a fluctuation…

Statistical Mechanics · Physics 2009-11-11 Paul Maragakis , Martin Spichty , Martin Karplus

Two recent topics on a formal thermodynamic analogy of intracellular diffusivity fluctuations observed experimentally in normal/anomalous diffusion are reported. Not only the analogs of the quantity of heat and work as well as the internal…

Statistical Mechanics · Physics 2026-04-22 Yuichi Itto

We propose a regularization framework inspired by thermodynamic work for guiding pre-trained probability flow generative models (e.g., continuous normalizing flows or diffusion models) by minimizing excess work, a concept rooted in…

We discuss an approach to determine averages of the work, dissipated heat and variation of internal energy of an open quantum system driven by an external classical field. These quantities are measured by coupling the quantum system to a…

Quantum Physics · Physics 2022-03-23 Paolo Solinas , Mirko Amico , Nino N. Zanghì

Characterizing and optimizing nanoscopic heat engines require an appropriate understanding of the interplay between power, efficiency, entropy production and fluctuations. Despite significant recent advancements, including linear stochastic…

Statistical Mechanics · Physics 2025-11-07 Gustavo A. L. Forão , Jonas Berx , Carlos E. Fiore

We introduce the idea of weakly coherent collisional models, where the elements of an environment interacting with a system of interest are prepared in states that are approximately thermal, but have an amount of coherence proportional to a…

Chemical processes in closed systems are poorly controllable since they always relax to equilibrium. Living systems avoid this fate and give rise to a much richer diversity of phenomena by operating under nonequilibrium conditions. Recent…

Chemical Physics · Physics 2019-09-11 Emanuele Penocchio , Riccardo Rao , Massimiliano Esposito

In the standard framework of thermodynamics the work produced or consumed in a process is a random variable whose average value is bounded by the change in the free energy of the system. This work is calculated without regard for the size…

Quantum Physics · Physics 2017-04-19 Jonathan G. Richens , Lluis Masanes

A central goal of thermodynamics is to identify optimal processes during which the least amount of energy is dissipated into the environment. Generally, even for simple systems, such as the parametric harmonic oscillator, optimal control…

Statistical Mechanics · Physics 2018-10-11 Marcus V. S. Bonança , Sebastian Deffner

A classical particle system coupled with a thermostat driven by an external constant force reaches its steady state when the ensemble-averaged drift velocity does not vary with time. The statistical mechanics of such a system is derived…

Statistical Mechanics · Physics 2020-12-02 Jie Yao , Yanting Wang

Finding parameters that minimise a loss function is at the core of many machine learning methods. The Stochastic Gradient Descent algorithm is widely used and delivers state of the art results for many problems. Nonetheless, Stochastic…

Machine Learning · Computer Science 2018-09-26 Yao Zhang , Andrew M. Saxe , Madhu S. Advani , Alpha A. Lee

Theoretical design of global optimization algorithms can profitably utilize recent statistical mechanical treatments of potential energy surfaces (PES's). Here we analyze a particular method to explain its success in locating global minima…

Statistical Mechanics · Physics 2008-02-03 Jonathan Doye , David Wales

The optimization of the conversion of thermal energy into work and the minimization of dissipation for nano- and mesoscopic systems is a complex challenge because of the important role fluctuations play on the dynamics of small systems. We…

Quantum Physics · Physics 2025-09-24 Alberto Rolandi

In this paper, we derive a number of inequalities which express power-efficiency trade-offs that hold generally for thermodynamic machines operating in non-equilibrium stationary states. One of these inequalities concerns the output power,…

Statistical Mechanics · Physics 2019-09-04 Hadrien Vroylandt , David Lacoste , Gatien Verley

In traditional thermodynamical and statistical-mechanical approaches one has (some) detailed knowledge of the principles governing the microdynamics of a system. However in many instances we may not have a Hamiltonian or good information…

Statistical Mechanics · Physics 2007-05-23 David Ford

Periodic driving is used to operate machines that go from standard macroscopic engines to small non-equilibrium micro-sized systems. Two classes of such systems are small heat engines driven by periodic temperature variations and molecular…

Statistical Mechanics · Physics 2017-11-16 Somrita Ray , Andre C. Barato

The efficiency of microscopic heat engines in a thermally heterogenous environment is considered. We show that, as a consequence of the recently discovered entropic anomaly, quasi-static engines, whose efficiency is maximal in a fluid at…

Statistical Mechanics · Physics 2015-06-12 Stefano Bo , Antonio Celani

We investigate the thermodynamics of integrable classical field theories under the effect of a random initial configuration, motivated by the nonequilibrium evolution of quantum field theories. The approach to thermal equilibrium is…

Statistical Mechanics · Physics 2016-10-05 P. E. G. Assis

An attempt toward the operational formulation of quantum thermodynamics is made by employing the recently proposed operations forming positive operator-valued measures for generating thermodynamic processes. The quantity of heat as well as…

Statistical Mechanics · Physics 2015-06-04 Sumiyoshi Abe , Yuki Aoyaghi

We investigate thermodynamics of general nonequilibrium processes stopped at stochastic times. We propose a systematic strategy for constructing fluctuation-theorem-like martingales for each thermodynamic functional, yielding a family of…

Statistical Mechanics · Physics 2023-06-02 Haoran Yang , Hao Ge