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Magnetic resonance imaging is a fundamental tool to reach a diagnosis of multiple sclerosis and monitoring its progression. Although several attempts have been made to segment multiple sclerosis lesions using artificial intelligence, fully…

Mining discriminative subgraph patterns from graph data has attracted great interest in recent years. It has a wide variety of applications in disease diagnosis, neuroimaging, etc. Most research on subgraph mining focuses on the graph…

Machine Learning · Computer Science 2016-11-15 Bokai Cao , Xiangnan Kong , Jingyuan Zhang , Philip S. Yu , Ann B. Ragin

Machine learning-based imaging diagnostics has recently reached or even superseded the level of clinical experts in several clinical domains. However, classification decisions of a trained machine learning system are typically…

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-24 Spyridon Bakas , Mauricio Reyes , Andras Jakab , Stefan Bauer , Markus Rempfler , Alessandro Crimi , Russell Takeshi Shinohara , Christoph Berger , Sung Min Ha , Martin Rozycki , Marcel Prastawa , Esther Alberts , Jana Lipkova , John Freymann , Justin Kirby , Michel Bilello , Hassan Fathallah-Shaykh , Roland Wiest , Jan Kirschke , Benedikt Wiestler , Rivka Colen , Aikaterini Kotrotsou , Pamela Lamontagne , Daniel Marcus , Mikhail Milchenko , Arash Nazeri , Marc-Andre Weber , Abhishek Mahajan , Ujjwal Baid , Elizabeth Gerstner , Dongjin Kwon , Gagan Acharya , Manu Agarwal , Mahbubul Alam , Alberto Albiol , Antonio Albiol , Francisco J. Albiol , Varghese Alex , Nigel Allinson , Pedro H. A. Amorim , Abhijit Amrutkar , Ganesh Anand , Simon Andermatt , Tal Arbel , Pablo Arbelaez , Aaron Avery , Muneeza Azmat , Pranjal B. , W Bai , Subhashis Banerjee , Bill Barth , Thomas Batchelder , Kayhan Batmanghelich , Enzo Battistella , Andrew Beers , Mikhail Belyaev , Martin Bendszus , Eze Benson , Jose Bernal , Halandur Nagaraja Bharath , George Biros , Sotirios Bisdas , James Brown , Mariano Cabezas , Shilei Cao , Jorge M. Cardoso , Eric N Carver , Adrià Casamitjana , Laura Silvana Castillo , Marcel Catà , Philippe Cattin , Albert Cerigues , Vinicius S. Chagas , Siddhartha Chandra , Yi-Ju Chang , Shiyu Chang , Ken Chang , Joseph Chazalon , Shengcong Chen , Wei Chen , Jefferson W Chen , Zhaolin Chen , Kun Cheng , Ahana Roy Choudhury , Roger Chylla , Albert Clérigues , Steven Colleman , Ramiro German Rodriguez Colmeiro , Marc Combalia , Anthony Costa , Xiaomeng Cui , Zhenzhen Dai , Lutao Dai , Laura Alexandra Daza , Eric Deutsch , Changxing Ding , Chao Dong , Shidu Dong , Wojciech Dudzik , Zach Eaton-Rosen , Gary Egan , Guilherme Escudero , Théo Estienne , Richard Everson , Jonathan Fabrizio , Yong Fan , Longwei Fang , Xue Feng , Enzo Ferrante , Lucas Fidon , Martin Fischer , Andrew P. French , Naomi Fridman , Huan Fu , David Fuentes , Yaozong Gao , Evan Gates , David Gering , Amir Gholami , Willi Gierke , Ben Glocker , Mingming Gong , Sandra González-Villá , T. Grosges , Yuanfang Guan , Sheng Guo , Sudeep Gupta , Woo-Sup Han , Il Song Han , Konstantin Harmuth , Huiguang He , Aura Hernández-Sabaté , Evelyn Herrmann , Naveen Himthani , Winston Hsu , Cheyu Hsu , Xiaojun Hu , Xiaobin Hu , Yan Hu , Yifan Hu , Rui Hua , Teng-Yi Huang , Weilin Huang , Sabine Van Huffel , Quan Huo , Vivek HV , Khan M. Iftekharuddin , Fabian Isensee , Mobarakol Islam , Aaron S. Jackson , Sachin R. Jambawalikar , Andrew Jesson , Weijian Jian , Peter Jin , V Jeya Maria Jose , Alain Jungo , B Kainz , Konstantinos Kamnitsas , Po-Yu Kao , Ayush Karnawat , Thomas Kellermeier , Adel Kermi , Kurt Keutzer , Mohamed Tarek Khadir , Mahendra Khened , Philipp Kickingereder , Geena Kim , Nik King , Haley Knapp , Urspeter Knecht , Lisa Kohli , Deren Kong , Xiangmao Kong , Simon Koppers , Avinash Kori , Ganapathy Krishnamurthi , Egor Krivov , Piyush Kumar , Kaisar Kushibar , Dmitrii Lachinov , Tryphon Lambrou , Joon Lee , Chengen Lee , Yuehchou Lee , M Lee , Szidonia Lefkovits , Laszlo Lefkovits , James Levitt , Tengfei Li , Hongwei Li , Wenqi Li , Hongyang Li , Xiaochuan Li , Yuexiang Li , Heng Li , Zhenye Li , Xiaoyu Li , Zeju Li , XiaoGang Li , Wenqi Li , Zheng-Shen Lin , Fengming Lin , Pietro Lio , Chang Liu , Boqiang Liu , Xiang Liu , Mingyuan Liu , Ju Liu , Luyan Liu , Xavier Llado , Marc Moreno Lopez , Pablo Ribalta Lorenzo , Zhentai Lu , Lin Luo , Zhigang Luo , Jun Ma , Kai Ma , Thomas Mackie , Anant Madabushi , Issam Mahmoudi , Klaus H. Maier-Hein , Pradipta Maji , CP Mammen , Andreas Mang , B. S. Manjunath , Michal Marcinkiewicz , S McDonagh , Stephen McKenna , Richard McKinley , Miriam Mehl , Sachin Mehta , Raghav Mehta , Raphael Meier , Christoph Meinel , Dorit Merhof , Craig Meyer , Robert Miller , Sushmita Mitra , Aliasgar Moiyadi , David Molina-Garcia , Miguel A. B. Monteiro , Grzegorz Mrukwa , Andriy Myronenko , Jakub Nalepa , Thuyen Ngo , Dong Nie , Holly Ning , Chen Niu , Nicholas K Nuechterlein , Eric Oermann , Arlindo Oliveira , Diego D. C. Oliveira , Arnau Oliver , Alexander F. I. Osman , Yu-Nian Ou , Sebastien Ourselin , Nikos Paragios , Moo Sung Park , Brad Paschke , J. Gregory Pauloski , Kamlesh Pawar , Nick Pawlowski , Linmin Pei , Suting Peng , Silvio M. Pereira , Julian Perez-Beteta , Victor M. Perez-Garcia , Simon Pezold , Bao Pham , Ashish Phophalia , Gemma Piella , G. N. Pillai , Marie Piraud , Maxim Pisov , Anmol Popli , Michael P. Pound , Reza Pourreza , Prateek Prasanna , Vesna Prkovska , Tony P. Pridmore , Santi Puch , Élodie Puybareau , Buyue Qian , Xu Qiao , Martin Rajchl , Swapnil Rane , Michael Rebsamen , Hongliang Ren , Xuhua Ren , Karthik Revanuru , Mina Rezaei , Oliver Rippel , Luis Carlos Rivera , Charlotte Robert , Bruce Rosen , Daniel Rueckert , Mohammed Safwan , Mostafa Salem , Joaquim Salvi , Irina Sanchez , Irina Sánchez , Heitor M. Santos , Emmett Sartor , Dawid Schellingerhout , Klaudius Scheufele , Matthew R. Scott , Artur A. Scussel , Sara Sedlar , Juan Pablo Serrano-Rubio , N. Jon Shah , Nameetha Shah , Mazhar Shaikh , B. Uma Shankar , Zeina Shboul , Haipeng Shen , Dinggang Shen , Linlin Shen , Haocheng Shen , Varun Shenoy , Feng Shi , Hyung Eun Shin , Hai Shu , Diana Sima , M Sinclair , Orjan Smedby , James M. Snyder , Mohammadreza Soltaninejad , Guidong Song , Mehul Soni , Jean Stawiaski , Shashank Subramanian , Li Sun , Roger Sun , Jiawei Sun , Kay Sun , Yu Sun , Guoxia Sun , Shuang Sun , Yannick R Suter , Laszlo Szilagyi , Sanjay Talbar , Dacheng Tao , Dacheng Tao , Zhongzhao Teng , Siddhesh Thakur , Meenakshi H Thakur , Sameer Tharakan , Pallavi Tiwari , Guillaume Tochon , Tuan Tran , Yuhsiang M. Tsai , Kuan-Lun Tseng , Tran Anh Tuan , Vadim Turlapov , Nicholas Tustison , Maria Vakalopoulou , Sergi Valverde , Rami Vanguri , Evgeny Vasiliev , Jonathan Ventura , Luis Vera , Tom Vercauteren , C. A. Verrastro , Lasitha Vidyaratne , Veronica Vilaplana , Ajeet Vivekanandan , Guotai Wang , Qian Wang , Chiatse J. Wang , Weichung Wang , Duo Wang , Ruixuan Wang , Yuanyuan Wang , Chunliang Wang , Guotai Wang , Ning Wen , Xin Wen , Leon Weninger , Wolfgang Wick , Shaocheng Wu , Qiang Wu , Yihong Wu , Yong Xia , Yanwu Xu , Xiaowen Xu , Peiyuan Xu , Tsai-Ling Yang , Xiaoping Yang , Hao-Yu Yang , Junlin Yang , Haojin Yang , Guang Yang , Hongdou Yao , Xujiong Ye , Changchang Yin , Brett Young-Moxon , Jinhua Yu , Xiangyu Yue , Songtao Zhang , Angela Zhang , Kun Zhang , Xuejie Zhang , Lichi Zhang , Xiaoyue Zhang , Yazhuo Zhang , Lei Zhang , Jianguo Zhang , Xiang Zhang , Tianhao Zhang , Sicheng Zhao , Yu Zhao , Xiaomei Zhao , Liang Zhao , Yefeng Zheng , Liming Zhong , Chenhong Zhou , Xiaobing Zhou , Fan Zhou , Hongtu Zhu , Jin Zhu , Ying Zhuge , Weiwei Zong , Jayashree Kalpathy-Cramer , Keyvan Farahani , Christos Davatzikos , Koen van Leemput , Bjoern Menze

Multiple sclerosis is one of the most common chronic neurological diseases affecting the central nervous system. Lesions produced by the MS can be observed through two modalities of magnetic resonance (MR), known as T2W and FLAIR sequences,…

Signal Processing · Electrical Eng. & Systems 2022-12-16 Antonio Falvo , Danilo Comminiello , Simone Scardapane , Michele Scarpiniti , Aurelio Uncini

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) that results in focal injury to the grey and white matter. The presence of white matter lesions biases morphometric analyses such as…

Computer Vision and Pattern Recognition · Computer Science 2019-09-09 Hao Xiong , Chaoyue Wang , Dacheng Tao , Michael Barnett , Chenyu Wang

Multiple sclerosis (MS) lesions occupy a small fraction of the brain volume, and are heterogeneous with regards to shape, size and locations, which poses a great challenge for training deep learning based segmentation models. We proposed a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Hang Zhang , Jinwei Zhang , Rongguang Wang , Qihao Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang

Background: Alzheimer's disease and related dementias (ADRD) ranks as the sixth leading cause of death in the US, underlining the importance of accurate ADRD risk prediction. While recent advancement in ADRD risk prediction have primarily…

Machine Learning · Computer Science 2024-06-11 Xinyue Hu , Zenan Sun , Yi Nian , Yichen Wang , Yifang Dang , Fang Li , Jingna Feng , Evan Yu , Cui Tao

Breast cancer is one of the most common cancers in women worldwide, and early detection can significantly reduce the mortality rate of breast cancer. It is crucial to take multi-scale information of tissue structure into account in the…

Computer Vision and Pattern Recognition · Computer Science 2021-01-01 Mo Zhang , Quanzheng Li

Early detection and segmentation of skin lesions is crucial for timely diagnosis and treatment, necessary to improve the survival rate of patients. However, manual delineation is time consuming and subject to intra- and inter-observer…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Sulaiman Vesal , Shreyas Malakarjun Patil , Nishant Ravikumar , Andreas Maier

Automated segmentation of multiple sclerosis (MS) lesions from MRI scans is important to quantify disease progression. In recent years, convolutional neural networks (CNNs) have shown top performance for this task when a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jiacheng Wang , Hao Li , Han Liu , Dewei Hu , Daiwei Lu , Keejin Yoon , Kelsey Barter , Francesca Bagnato , Ipek Oguz

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

Computer Vision and Pattern Recognition · Computer Science 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…

Computer Vision and Pattern Recognition · Computer Science 2017-05-03 Yehui Yang , Tao Li , Wensi Li , Haishan Wu , Wei Fan , Wensheng Zhang

Alzheimer's disease (AD) is a neurodegenerative disorder that affects more than seven million people in the United States alone. AD currently has no cure, but there are ways to potentially slow its progression if caught early enough. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Mahdi Moghaddami , Mohammad-Reza Siadat , Austin Toma , Connor Laming , Huirong Fu

The detection of new multiple sclerosis (MS) lesions is an important marker of the evolution of the disease. The applicability of learning-based methods could automate this task efficiently. However, the lack of annotated longitudinal data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Reda Abdellah Kamraoui , Boris Mansencal , José V Manjon , Pierrick Coupé

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Tremendous recent literature show that associations between different brain regions, i.e., brain connectivity, provide early symptoms of neurological disorders. Despite significant efforts made for graph neural network (GNN) techniques,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Xin Ma , Guorong Wu , Seong Jae Hwang , Won Hwa Kim

In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

The diagnosis, prognosis, and treatment of patients with musculoskeletal (MSK) disorders require radiology imaging (using computed tomography, magnetic resonance imaging(MRI), and ultrasound) and their precise analysis by expert…

Image and Video Processing · Electrical Eng. & Systems 2020-03-03 Ismail Irmakci , Syed Muhammad Anwar , Drew A. Torigian , Ulas Bagci