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This paper introduces a novel optimization framework for deep neural network (DNN) hardware accelerators, enabling the rapid development of customized and automated design flows. More specifically, our approach aims to automate the…

Machine Learning · Computer Science 2023-11-08 Zhiqiang Que , Shuo Liu , Markus Rognlien , Ce Guo , Jose G. F. Coutinho , Wayne Luk

The automation of analog integrated circuit (IC) design remains a longstanding challenge, primarily due to the intricate interdependencies among physical layout, parasitic effects, and circuit-level performance. These interactions impose…

Machine Learning · Computer Science 2026-01-28 Giuseppe Chiari , Michele Piccoli , Davide Zoni

In situ polymerization and micropatterning of hydrogels on-chip opens the potential for many applications such as tracking and controlling the diffusion of molecules, stimulants, inhibitors, as well as nutrients and drugs, from their source…

The rapidly advancing fields of statistical modeling and machine learning have significantly enhanced data-driven design and optimization. This paper focuses on leveraging these design algorithms to optimize a medical walker, an integral…

Machine Learning · Computer Science 2023-10-31 Advaith Narayanan

Quantitatively predictive models of biomolecular circuits are important tools for the design of synthetic biology and molecular communication circuits. The information content of typical time-lapse single-cell data for the inference of…

Molecular Networks · Quantitative Biology 2021-01-11 Tim Prangemeier , Christian Wildner , Maleen Hanst , Heinz Koeppl

The transport and manipulation of particles and cells in microfluidic devices has become a core methodology in domains ranging from molecular biology to manufacturing and drug design. The rational design and operation of such devices can…

Computational Engineering, Finance, and Science · Computer Science 2020-07-15 Dmitry Alexeev , Lucas Amoudruz , Sergey Litvinov , Petros Koumoutsakos

Data Pipeline plays an indispensable role in tasks such as modeling machine learning and developing data products. With the increasing diversification and complexity of Data sources, as well as the rapid growth of data volumes, building an…

Machine Learning · Computer Science 2024-02-21 Jiang Wu , Hongbo Wang , Chunhe Ni , Chenwei Zhang , Wenran Lu

In the field of global optimization, many existing algorithms face challenges posed by non-convex target functions and high computational complexity or unavailability of gradient information. These limitations, exacerbated by sensitivity to…

Optimization and Control · Mathematics 2023-10-16 Xinyu Zhang , Sujit Ghosh

Data movement is the dominating factor affecting performance and energy in modern computing systems. Consequently, many algorithms have been developed to minimize the number of I/O operations for common computing patterns. Matrix…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-26 Johannes de Fine Licht , Grzegorz Kwasniewski , Torsten Hoefler

Scalable technologies for the production of bio-compatible complex microfibers with controllable size and composition at competitively high throughput are urgently needed in order to meet the growing demand for such microstructures in…

Applied Physics · Physics 2022-08-11 Marangon Francesco , Baumgartner David , Planchette Carole

High-energy physics experiments face extreme data rates, requiring real-time trigger systems to reduce event throughput while preserving sensitivity to rare processes. Trigger systems are typically constructed as modular chains of…

High Energy Physics - Experiment · Physics 2026-03-10 Noah Clarke Hall , Ioannis Xiotidis , Nikos Konstantinidis , David W. Miller

This paper considers the problem of regulating a linear dynamical system to the solution of a convex optimization problem with an unknown or partially-known cost. We design a data-driven feedback controller - based on gradient flow dynamics…

Optimization and Control · Mathematics 2022-04-05 Liliaokeawawa Cothren , Gianluca Bianchin , Emiliano Dall'Anese

The classical optimal power flow problem optimizes the power flow in a power network considering the associated flow and operating constraints. In this paper, we investigate optimal power flow in the context of utility-maximizing demand…

Data Structures and Algorithms · Computer Science 2018-03-22 Majid Khonji , Chi-Kin Chau , Khaled Elbassioni

In this paper, we address the problem of coordinating a set of distributed energy resources (DERs) to regulate voltage in power distribution systems to desired levels. To this end, we formulate the voltage control problem as an optimization…

Optimization and Control · Mathematics 2020-06-09 Hanchen Xu , Alejandro D. Domínguez-García , Peter W. Sauer

High-Level Synthesis (HLS) serves as an agile hardware development tool that streamlines the circuit design by abstracting the register transfer level into behavioral descriptions, while allowing designers to customize the generated…

Hardware Architecture · Computer Science 2025-06-03 Runkai Li , Jia Xiong , Xi Wang

Innovative membrane technologies optimally integrated into large separation process plants are essential for economical water treatment and disposal. However, the mass transport through membranes is commonly described by nonlinear…

The optimal selection of experimental conditions is essential to maximizing the value of data for inference and prediction, particularly in situations where experiments are time-consuming and expensive to conduct. We propose a general…

Machine Learning · Statistics 2012-12-04 Xun Huan , Youssef M. Marzouk

The problem of computing an exact experimental design that is optimal for the least-squares estimation of the parameters of a regression model is considered. We show that this problem can be solved via mixed-integer linear programming…

Computation · Statistics 2024-06-18 Radoslav Harman , Samuel Rosa

In the pursuit of sustainable manufacturing, ultra-short pulse laser micromachining stands out as a promising solution while also offering high-precision and qualitative laser processing. However, unlocking the full potential of ultra-short…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Luis Correas-Naranjo , Miguel Camacho-Sánchez , Laëtitia Launet , Milena Zuric , Valery Naranjo

We present variants of the Conjugate Gradient (CG), Conjugate Residual (CR), and Generalized Minimal Residual (GMRES) methods which are both pipelined and flexible. These allow computation of inner products and norms to be overlapped with…

Numerical Analysis · Mathematics 2016-09-16 Patrick Sanan , Sascha M. Schnepp , Dave. A. May