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Many questions in Data Science are fundamentally causal in that our objective is to learn the effect of some exposure, randomized or not, on an outcome interest. Even studies that are seemingly non-causal, such as those with the goal of…

Applications · Statistics 2021-07-02 Hachem Saddiki , Laura B. Balzer

Single-cell RNA-seq data allow the quantification of cell type differences across a growing set of biological contexts. However, pinpointing a small subset of genomic features explaining this variability can be ill-defined and…

Machine Learning · Statistics 2022-07-29 Nabeel Sarwar , Wilson Gregory , George A Kevrekidis , Soledad Villar , Bianca Dumitrascu

Existing plant disease classification models have achieved remarkable performance in recognizing in-laboratory diseased images. However, their performance often significantly degrades in classifying in-the-wild images. Furthermore, we…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Tianqi Wei , Zhi Chen , Zi Huang , Xin Yu

Despite the wealth of single-cell multi-omics data, it remains challenging to predict the consequences of novel genetic and chemical perturbations in the human body. It requires knowledge of molecular interactions at all biological levels,…

Artificial Intelligence · Computer Science 2025-01-22 You Wu , Lei Xie

A fundamental bottleneck in utilising complex machine learning systems for critical applications has been not knowing why they do and what they do, thus preventing the development of any crucial safety protocols. To date, no method exist…

Machine Learning · Computer Science 2023-01-18 Jan Rosenzweig , Zoran Cvetkovic , Ivana Rosenzweig

In this work, we look at a two-sample problem within the framework of Gaussian graphical models. When the global hypothesis of equality of two distributions is rejected, the interest is usually in localizing the source of difference.…

Methodology · Statistics 2021-11-29 Vera Djordjilović , Monica Chiogna

Causal Bayesian Networks (CBNs) are an important tool for reasoning under uncertainty in complex real-world systems. Determining the graphical structure of a CBN remains a key challenge and is undertaken either by eliciting it from humans,…

Artificial Intelligence · Computer Science 2023-10-18 Neville K Kitson , Anthony C Constantinou

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

The uptake of machine learning (ML) approaches in the social and health sciences has been rather slow, and research using ML for social and health research questions remains fragmented. This may be due to the separate development of…

Progress in probabilistic generative models has accelerated, developing richer models with neural architectures, implicit densities, and with scalable algorithms for their Bayesian inference. However, there has been limited progress in…

Machine Learning · Statistics 2017-10-31 Dustin Tran , David M. Blei

Medication recommendation systems are developed to recommend suitable medications tailored to specific patient. Previous researches primarily focus on learning medication representations, which have yielded notable advances. However, these…

Artificial Intelligence · Computer Science 2024-07-23 Xiang Li , Shunpan Liang , Yu Lei , Chen Li , Yulei Hou , Tengfei Ma

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

For a given causal question, it is important to efficiently decide which causal inference method to use for a given dataset. This is challenging because causal methods typically rely on complex and difficult-to-verify assumptions, and…

Machine Learning · Computer Science 2023-11-09 Shantanu Gupta , Cheng Zhang , Agrin Hilmkil

Recent work has shown success in incorporating pre-trained models like BERT to improve NLP systems. However, existing pre-trained models lack of causal knowledge which prevents today's NLP systems from thinking like humans. In this paper,…

Computation and Language · Computer Science 2021-08-10 Zhongyang Li , Xiao Ding , Kuo Liao , Bing Qin , Ting Liu

Causal discovery studies the problem of mining causal relationships between variables from data, which is of primary interest in science. During the past decades, significant amount of progresses have been made toward this fundamental data…

Artificial Intelligence · Computer Science 2016-11-28 Kui Yu , Jiuyong Li , Lin Liu

Causal structure learning from observational data remains a non-trivial task due to various factors such as finite sampling, unobserved confounding factors, and measurement errors. Constraint-based and score-based methods tend to suffer…

Machine Learning · Computer Science 2022-11-09 Rezaur Rashid , Jawad Chowdhury , Gabriel Terejanu

Beneficial to advanced computing devices, models with massive parameters are increasingly employed to extract more information to enhance the precision in describing and predicting the patterns of objective systems. This phenomenon is…

Information Theory · Computer Science 2024-03-08 Liye Jia , Fengyufan Yang , Ka Lok Man , Erick Purwanto , Sheng-Uei Guan , Jeremy Smith , Yutao Yue

In causal inference, interference occurs when the treatment of one unit may affect the outcomes of other units. The goal of this work is to serve as a guide to the use of linear outcome modeling for estimating causal effects in settings…

Methodology · Statistics 2026-04-01 Eric Tong , Salvador V. Balkus

Causal identification is at the core of the causal inference literature, where complete algorithms have been proposed to identify causal queries of interest. The validity of these algorithms hinges on the restrictive assumption of having…

Machine Learning · Computer Science 2023-10-30 Sina Akbari , Fateme Jamshidi , Ehsan Mokhtarian , Matthew J. Vowels , Jalal Etesami , Negar Kiyavash