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Computational Pathology (CPath) is an emerging field concerned with the study of tissue pathology via computational algorithms for the processing and analysis of digitized high-resolution images of tissue slides. Recent deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2021-12-20 Amina Asif , Kashif Rajpoot , David Snead , Fayyaz Minhas , Nasir Rajpoot

BACKGROUND: Proptosis is characterized by a protrusion of the eyeball due to an increase of the orbital tissue volume. To recover a normal eyeball positioning, the most frequent surgical technique consists in the osteotomy of orbital walls…

Medical Physics · Physics 2007-05-23 Vincent Luboz , Dominique Ambard , Pascal Swider , Franck Boutault , Yohan Payan

Clinical pathways are specialized healthcare plans that model patient treatment procedures. They are developed to provide criteria-based progression and standardize patient treatment, thereby improving care, reducing resource use, and…

Machine Learning · Computer Science 2025-12-04 Francesco Vitale , Nicola Mazzocca

The scientific computation methods development in conjunction with artificial intelligence technologies remains a hot research topic. Finding a balance between lightweight and accurate computations is a solid foundation for this direction.…

Machine Learning · Computer Science 2025-07-03 Nikita Sakovich , Dmitry Aksenov , Ekaterina Pleshakova , Sergey Gataullin

Chronic diseases constitute the principal burden of morbidity, mortality, and healthcare costs worldwide, yet current health systems remain fragmented and predominantly reactive. Patient Medical Digital Twins (PMDTs) offer a paradigm shift:…

Software Engineering · Computer Science 2026-02-13 Micheal P. Papazoglou , Bernd J. Krämer , Mira Raheem , Amal Elgammal

When it comes to clinical survival trials, regulatory restrictions usually require the application of methods that solely utilize baseline covariates and the intention-to-treat principle. Thereby a lot of potentially useful information is…

Multiscale models allow for the treatment of complex phenomena involving different scales, such as remodeling and growth of tissues, muscular activation, and cardiac electrophysiology. Numerous numerical approaches have been developed to…

Numerical Analysis · Mathematics 2018-06-28 Marco Favino , Alessio Quaglino , Sonia Pozzi , Rolf Krause , Igor Pivkin

Dataset condensation (DC) learns a compact synthetic dataset that enables models to match the performance of full-data training, prioritising utility over distributional fidelity. While typically explored for computational efficiency, DC…

Motivation: Peptides have attracted the attention in this century due to their remarkable therapeutic properties. Computational tools are being developed to take advantage of existing information, encapsulating knowledge and making it…

Medical Informatics and the application of modern signal processing in the assistance of the diagnostic process in medical imaging is one of the more recent and active research areas today. This thesis addresses a variety of issues related…

Computer Vision and Pattern Recognition · Computer Science 2009-10-20 Harris Georgiou

The complexity of droplet microfluidics grows by implementing parallel processes and multiple functionalities on a single device. This poses a challenge to the engineer designing the microfluidic networks. In today's design processes, the…

Fluid Dynamics · Physics 2018-10-03 Andreas Grimmer , Medina Hamidović , Werner Haselmayr , Robert Wille

In the big data era, integrating diverse data modalities poses significant challenges, particularly in complex fields like healthcare. This paper introduces a new process model for multimodal Data Fusion for Data Mining, integrating…

Artificial Intelligence · Computer Science 2024-06-04 David Restrepo , Chenwei Wu , Constanza Vásquez-Venegas , Luis Filipe Nakayama , Leo Anthony Celi , Diego M López

In the history of computer-aided design (CAD), feature-based parametric modeling and boundary representation-based direct modeling are two of the most important CAD paradigms, developed respectively in the late 1980s and the late 2000s.…

Graphics · Computer Science 2025-05-30 Qiang Zou

The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of…

Optimization and Control · Mathematics 2014-11-20 Louise Reips , Martin Burger , Ralf Engbers

Despite the remarkable advances in cancer diagnosis, treatment, and management that have occurred over the past decade, malignant tumors remain a major public health problem. Further progress in combating cancer may be enabled by…

Deep learning has received extensive research interest in developing new medical image processing algorithms, and deep learning based models have been remarkably successful in a variety of medical imaging tasks to support disease detection…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Xuxin Chen , Ximin Wang , Ke Zhang , Kar-Ming Fung , Theresa C. Thai , Kathleen Moore , Robert S. Mannel , Hong Liu , Bin Zheng , Yuchen Qiu

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

With the ever-growing complexity of models in the field of remote sensing (RS), there is an increasing demand for solutions that balance model accuracy with computational efficiency. Knowledge distillation (KD) has emerged as a powerful…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Yassine Himeur , Nour Aburaed , Omar Elharrouss , Iraklis Varlamis , Shadi Atalla , Wathiq Mansoor , Hussain Al Ahmad

To empower users of wearable medical devices, it is important to enable methods that facilitate reflection on previous care to improve future outcomes. In this work, we conducted a two-phase user-study involving patients, caregivers, and…

Computers and Society · Computer Science 2020-07-28 Temiloluwa Prioleau , Ashutosh Sabharwal , Madhuri M. Vasudevan