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The rapid advancement of large language models (LLMs) in biological-medical applications has highlighted a gap between their potential and the limited scale and often low quality of available open-source annotated textual datasets. In…

Computation and Language · Computer Science 2025-12-19 Xunxin Cai , Chengrui Wang , Qingqing Long , Yuanchun Zhou , Meng Xiao

Existing Protein Language Models (PLMs) often suffer from limited adaptability to multiple tasks and exhibit poor generalization across diverse biological contexts. In contrast, general-purpose Large Language Models (LLMs) lack the…

Machine Learning · Computer Science 2026-02-23 Yujia Wang , Jihong Guan , Wengen Li , Shuigeng Zhou , Xuhong Wang

Large Language Models (LLMs), such as GPT3.5, have exhibited remarkable proficiency in comprehending and generating natural language. On the other hand, medical assistants hold the potential to offer substantial benefits for individuals.…

Computation and Language · Computer Science 2024-04-05 Kai Zhang , Yangyang Kang , Fubang Zhao , Xiaozhong Liu

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

With the advancement of large language models (LLMs), the biomedical domain has seen significant progress and improvement in multiple tasks such as biomedical question answering, lay language summarization of the biomedical literature,…

Information Retrieval · Computer Science 2024-12-17 Deepak Gupta , Dina Demner-Fushman , William Hersh , Steven Bedrick , Kirk Roberts

Entity alignment is to find identical entities in different knowledge graphs (KGs) that refer to the same real-world object. Embedding-based entity alignment techniques have been drawing a lot of attention recently because they can help…

Computation and Language · Computer Science 2022-11-08 Xiaobin Tian , Zequn Sun , Guangyao Li , Wei Hu

The exponential growth of biomedical texts such as biomedical literature and electronic health records (EHRs), poses a significant challenge for clinicians and researchers to access clinical information efficiently. To tackle this…

Computation and Language · Computer Science 2023-07-17 Qianqian Xie , Zheheng Luo , Benyou Wang , Sophia Ananiadou

Knowledge graphs (KGs) contain rich information about world knowledge, entities and relations. Thus, they can be great supplements to existing pre-trained language models. However, it remains a challenge to efficiently integrate information…

Computation and Language · Computer Science 2020-10-05 Donghan Yu , Chenguang Zhu , Yiming Yang , Michael Zeng

Language models (LMs) are typically trained once on a large-scale corpus and used for years without being updated. However, in a dynamic world, new entities constantly arise. We propose a framework to analyze what LMs can infer about new…

Computation and Language · Computer Science 2022-05-06 Yasumasa Onoe , Michael J. Q. Zhang , Eunsol Choi , Greg Durrett

In this work, we formulate the NER task as a multi-answer knowledge guided QA task (KGQA) which helps to predict entities only by assigning B, I and O tags without associating entity types with the tags. We provide different knowledge…

Computation and Language · Computer Science 2020-09-21 Pratyay Banerjee , Kuntal Kumar Pal , Murthy Devarakonda , Chitta Baral

Objective: To develop a high-throughput biomedical relation extraction system that takes advantage of the large language models'(LLMs) reading comprehension ability and biomedical world knowledge in a scalable and evidential manner.…

Computation and Language · Computer Science 2024-03-27 Songchi Zhou , Sheng Yu

When we integrate factual knowledge from knowledge graphs (KGs) into large language models (LLMs) to enhance their performance, the cost of injection through training increases with the scale of the models. Consequently, there is…

Computation and Language · Computer Science 2025-01-24 Xinbang Dai , Yuncheng Hua , Tongtong Wu , Yang Sheng , Qiu Ji , Guilin Qi

Large language models (LLMs) often require vast amounts of text to effectively acquire new knowledge. While continuing pre-training on large corpora or employing retrieval-augmented generation (RAG) has proven successful, updating an LLM…

Computation and Language · Computer Science 2025-08-11 Hugo Abonizio , Thales Almeida , Roberto Lotufo , Rodrigo Nogueira

State-of-the-art deep learning entity linking methods rely on extensive human-labelled data, which is costly to acquire. Current datasets are limited in size, leading to inadequate coverage of biomedical concepts and diminished performance…

Computation and Language · Computer Science 2024-10-23 Pedro Ruas , Fernando Gallego , Francisco J. Veredas , Francisco M. Couto

To tackle the problem of domain-specific knowledge scarcity within large language models (LLMs), knowledge graph-retrievalaugmented method has been proven to be an effective and efficient technique for knowledge infusion. However, existing…

Computation and Language · Computer Science 2024-06-07 Zhouyu Jiang , Ling Zhong , Mengshu Sun , Jun Xu , Rui Sun , Hui Cai , Shuhan Luo , Zhiqiang Zhang

Entity Alignment (EA) is vital for integrating diverse knowledge graph (KG) data, playing a crucial role in data-driven AI applications. Traditional EA methods primarily rely on comparing entity embeddings, but their effectiveness is…

Computation and Language · Computer Science 2024-10-11 Xuhui Jiang , Yinghan Shen , Zhichao Shi , Chengjin Xu , Wei Li , Zixuan Li , Jian Guo , Huawei Shen , Yuanzhuo Wang

External knowledge,e.g., entities and entity descriptions, can help humans understand texts. Many works have been explored to include external knowledge in the pre-trained models. These methods, generally, design pre-training tasks and…

Computation and Language · Computer Science 2022-08-19 Qinghua Zhao , Shuai Ma , Yuxuan Lei

Cross-lingual entity linking (XEL) grounds named entities in a source language to an English Knowledge Base (KB), such as Wikipedia. XEL is challenging for most languages because of limited availability of requisite resources. However, much…

Computation and Language · Computer Science 2019-10-02 Shuyan Zhou , Shruti Rijhwani , Graham Neubig

Entity synonyms discovery is crucial for entity-leveraging applications. However, existing studies suffer from several critical issues: (1) the input mentions may be out-of-vocabulary (OOV) and may come from a different semantic space of…

Artificial Intelligence · Computer Science 2021-04-02 Yiying Yang , Xi Yin , Haiqin Yang , Xingjian Fei , Hao Peng , Kaijie Zhou , Kunfeng Lai , Jianping Shen

Many fundamental problems in natural language processing rely on determining what entities appear in a given text. Commonly referenced as entity linking, this step is a fundamental component of many NLP tasks such as text understanding,…

Computation and Language · Computer Science 2016-02-01 Octavian-Eugen Ganea , Marina Ganea , Aurelien Lucchi , Carsten Eickhoff , Thomas Hofmann
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