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Neural network-based anomaly detection remains challenging in clinical applications with little or no supervised information and subtle anomalies such as hardly visible brain lesions. Among unsupervised methods, patch-based auto-encoders…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nicolas Pinon , Geoffroy Oudoumanessah , Robin Trombetta , Michel Dojat , Florence Forbes , Carole Lartizien

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Anomaly detection (AD) plays a crucial role in various domains, including cybersecurity, finance, and healthcare, by identifying patterns or events that deviate from normal behaviour. In recent years, significant progress has been made in…

Machine Learning · Computer Science 2024-01-24 Hadi Hojjati , Thi Kieu Khanh Ho , Narges Armanfard

Anomaly detection for time-series data has been an important research field for a long time. Seminal work on anomaly detection methods has been focussing on statistical approaches. In recent years an increasing number of machine learning…

Machine Learning · Computer Science 2020-04-02 Mohammad Braei , Sebastian Wagner

The goal of anomaly detection is to identify anomalous samples from normal ones. In this paper, a small number of anomalies are assumed to be available at the training stage, but they are assumed to be collected only from several anomaly…

Machine Learning · Computer Science 2022-05-03 Bowen Tian , Qinliang Su , Jian Yin

We developed a tool for detecting domain shifts, namely subtle differences in the probability distributions of datasets. We identify these shifts using an algorithm designed to detect localised density anomalies in high-dimensional feature…

Machine Learning · Statistics 2026-05-18 Sebastian Springer , Alessandro Laio

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

Recently, the research community of computerized medical imaging has started to discuss and address potential fairness issues that may emerge when developing and deploying AI systems for medical image analysis. This chapter covers some of…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Enzo Ferrante , Rodrigo Echeveste

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

Computer-aided diagnostics has benefited from the development of deep learning-based computer vision techniques in these years. Traditional supervised deep learning methods assume that the test sample is drawn from the identical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zesheng Hong , Yubiao Yue , Yubin Chen , Lele Cong , Huanjie Lin , Yuanmei Luo , Mini Han Wang , Weidong Wang , Jialong Xu , Xiaoqi Yang , Hechang Chen , Zhenzhang Li , Sihong Xie

Weakly-supervised diffusion models (DMs) in anomaly segmentation, leveraging image-level labels, have attracted significant attention for their superior performance compared to unsupervised methods. It eliminates the need for pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Yiming Che , Fazle Rafsani , Jay Shah , Md Mahfuzur Rahman Siddiquee , Teresa Wu

In medical imaging, un-, semi-, or self-supervised pathology detection is often approached with anomaly- or out-of-distribution detection methods, whose inductive biases are not intentionally directed towards detecting pathologies, and are…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Felix Meissen , Georgios Kaissis , Daniel Rueckert

Modern machine learning tools offer exciting possibilities to qualitatively change the paradigm for new particle searches. In particular, new methods can broaden the search program by gaining sensitivity to unforeseen scenarios by learning…

High Energy Physics - Phenomenology · Physics 2020-10-29 Benjamin Nachman

Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…

Machine Learning · Computer Science 2025-04-29 Haroui Ma , Francesco Quinzan , Theresa Willem , Stefan Bauer

Medical image diagnosis can be achieved by deep neural networks, provided there is enough varied training data for each disease class. However, a hitherto unknown disease class not encountered during training will inevitably be…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Mohammadreza Mohseni , Jordan Yap , William Yolland , Majid Razmara , M Stella Atkins

Artificial intelligence (AI) is increasingly being used for medical imaging tasks. However, there can be biases in AI models, particularly when they are trained using imbalanced training datasets. One such example has been the strong…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Tiarna Lee , Esther Puyol-Antón , Bram Ruijsink , Pier-Giorgio Masci , Louise Keehn , Phil Chowienczyk , Emily Haseler , Miaojing Shi , Andrew P. King

We propose the Autoencoding Binary Classifiers (ABC), a novel supervised anomaly detector based on the Autoencoder (AE). There are two main approaches in anomaly detection: supervised and unsupervised. The supervised approach accurately…

Machine Learning · Statistics 2019-03-27 Yuki Yamanaka , Tomoharu Iwata , Hiroshi Takahashi , Masanori Yamada , Sekitoshi Kanai

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang