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It is widely recognized that deep neural networks are sensitive to bias in the data. This means that during training these models are likely to learn spurious correlations between data and labels, resulting in limited generalization…

Machine Learning · Computer Science 2024-12-06 Vito Paolo Pastore , Massimiliano Ciranni , Davide Marinelli , Francesca Odone , Vittorio Murino

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Medical anomaly detection is a crucial yet challenging task aimed at recognizing abnormal images to assist in diagnosis. Due to the high-cost annotations of abnormal images, most methods utilize only known normal images during training and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yu Cai , Hao Chen , Xin Yang , Yu Zhou , Kwang-Ting Cheng

Obtaining labels for medical (image) data requires scarce and expensive experts. Moreover, due to ambiguous symptoms, single images rarely suffice to correctly diagnose a medical condition. Instead, it often requires to take additional…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Diana Davletshina , Valentyn Melnychuk , Viet Tran , Hitansh Singla , Max Berrendorf , Evgeniy Faerman , Michael Fromm , Matthias Schubert

Anomaly detection (AD) is the machine learning task of identifying highly discrepant abnormal samples by solely relying on the consistency of the normal training samples. Under the constraints of a distribution shift, the assumption that…

Machine Learning · Computer Science 2023-12-25 João B. S. Carvalho , Mengtao Zhang , Robin Geyer , Carlos Cotrini , Joachim M. Buhmann

Brain pathologies can vary greatly in size and shape, ranging from few pixels (i.e. MS lesions) to large, space-occupying tumors. Recently proposed Autoencoder-based methods for unsupervised anomaly segmentation in brain MRI have shown…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Anomaly detection is a field of intense research. Identifying low probability events in data/images is a challenging problem given the high-dimensionality of the data, especially when no (or little) information about the anomaly is…

Machine Learning · Computer Science 2022-04-13 José A. Padrón-Hidalgo , Valero Laparra , Gustau Camps-Valls

It has recently been shown that deep learning models for anatomical segmentation in medical images can exhibit biases against certain sub-populations defined in terms of protected attributes like sex or ethnicity. In this context, auditing…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Nicolás Gaggion , Rodrigo Echeveste , Lucas Mansilla , Diego H. Milone , Enzo Ferrante

In line with the development of Industry 4.0, surface defect detection/anomaly detection becomes a topical subject in the industry field. Improving efficiency as well as saving labor costs has steadily become a matter of great concern in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Yajie Cui , Zhaoxiang Liu , Shiguo Lian

The detection and localization of anomalies is one important medical image analysis task. Most commonly, Computer Vision anomaly detection approaches rely on manual annotations that are both time consuming and expensive to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Sergio Naval Marimont , Giacomo Tarroni

Algorithmic bias in medical imaging can perpetuate health disparities, yet its causes remain poorly understood in segmentation tasks. While fairness has been extensively studied in classification, segmentation remains underexplored despite…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Aditya Parikh , Sneha Das , Aasa Feragen

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Lesion detection in brain Magnetic Resonance Images (MRI) remains a challenging task. State-of-the-art approaches are mostly based on supervised learning making use of large annotated datasets. Human beings, on the other hand, even…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Xiaoran Chen , Ender Konukoglu

Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas

It can be challenging to identify brain MRI anomalies using supervised deep-learning techniques due to anatomical heterogeneity and the requirement for pixel-level labeling. Unsupervised anomaly detection approaches provide an alternative…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Hasan Iqbal , Umar Khalid , Jing Hua , Chen Chen

This article investigates the critical issue of dataset bias in medical imaging, with a particular emphasis on racial disparities caused by uneven population distribution in dataset collection. Our analysis reveals that medical segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Yixiao Chen , Yue Yao , Ruining Yang , Md Zakir Hossain , Ashu Gupta , Tom Gedeon

This review explores anomaly localization in medical images using denoising diffusion models. After providing a brief methodological background of these models, including their application to image reconstruction and their conditioning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Cosmin I. Bercea , Philippe C. Cattin , Julia A. Schnabel , Julia Wolleb

Early detection of anomalies in medical images such as brain MRI is highly relevant for diagnosis and treatment of many conditions. Supervised machine learning methods are limited to a small number of pathologies where there is good…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Alexander Frotscher , Jaivardhan Kapoor , Thomas Wolfers , Christian F. Baumgartner

Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…