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Today, the optimal performance of existing noise-suppression algorithms, both data-driven and those based on classic statistical methods, is range bound to specific levels of instantaneous input signal-to-noise ratios. In this paper, we…

Machine Learning · Computer Science 2018-07-30 Rasool Fakoor , Xiaodong He , Ivan Tashev , Shuayb Zarar

Immune cells recognize and discriminate antigens through immunological synapses - dynamic intercellular junctions exhibiting highly organized receptor-ligand patterns. While much work has focused on molecular kinetics and passive mechanisms…

Cell Behavior · Quantitative Biology 2025-10-22 Tony Wong , Tom Chou , Suraj Shankar , Shenshen Wang

Synaptic delays play a crucial role in biological neuronal networks, where their modulation has been observed in mammalian learning processes. In the realm of neuromorphic computing, although spiking neural networks (SNNs) aim to emulate…

Neural and Evolutionary Computing · Computer Science 2025-06-19 Marissa Dominijanni , Alexander Ororbia , Kenneth W. Regan

In many normative theories of synaptic plasticity, weight updates implicitly depend on the chosen parametrization of the weights. This problem relates, for example, to neuronal morphology: synapses which are functionally equivalent in terms…

Neurons and Cognition · Quantitative Biology 2022-02-25 Elena Kreutzer , Walter M. Senn , Mihai A. Petrovici

Spiking neural networks (SNNs) employing unsupervised learning methods inspired by neural plasticity are expected to be a new framework for artificial intelligence. In this study, we investigated the effect of multiple types of neural…

Neural and Evolutionary Computing · Computer Science 2026-01-19 Shinnosuke Touda , Hirotsugu Okuno

Human learning is a complex phenomenon requiring flexibility to adapt existing brain function and precision in selecting new neurophysiological activities to drive desired behavior. These two attributes -- flexibility and selection -- must…

Neurons and Cognition · Quantitative Biology 2013-06-28 Danielle S. Bassett , Nicholas F. Wymbs , Mason A. Porter , Peter J. Mucha , Jean M. Carlson , Scott T. Grafton

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

Neurons and Cognition · Quantitative Biology 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

Biological populations are subject to fluctuating environmental conditions. Different adaptive strategies can allow them to cope with these fluctuations: specialization to one particular environmental condition, adoption of a generalist…

Populations and Evolution · Quantitative Biology 2017-09-27 Andreas Mayer , Thierry Mora , Olivier Rivoire , Aleksandra M. Walczak

Feedback alignment and related weight-transport-free algorithms are often proposed as biologically plausible alternatives to backpropagation, yet they are typically formulated in discrete phases with implicitly synchronized forward and…

Machine Learning · Computer Science 2026-03-03 Marc Gong Bacvanski , Liu Ziyin , Tomaso Poggio

Understanding how biological neural networks carry out learning using spike-based local plasticity mechanisms can lead to the development of powerful, energy-efficient, and adaptive neuromorphic processing systems. A large number of…

Neural and Evolutionary Computing · Computer Science 2022-11-08 Lyes Khacef , Philipp Klein , Matteo Cartiglia , Arianna Rubino , Giacomo Indiveri , Elisabetta Chicca

Traveling waves of neural activity emerge in cortical networks both spontaneously and in response to stimuli. The spatiotemporal structure of waves can indicate the information they encode and the physiological processes that sustain them.…

Neurons and Cognition · Quantitative Biology 2023-12-12 Sage Shaw , Zachary P Kilpatrick

A generalized version of the Wilson-Cowan (WC) model is proposed which accounts for the evolution of the synaptic resources. Adiabatic elimination of the fast variables is performed to yield a simplified framework for the coupled…

Disordered Systems and Neural Networks · Physics 2025-11-21 Tommaso Trabocchi , Raffaella Burioni , Lucilla de Arcangelis , Duccio Fanelli

Color Appearance Models are biological networks that consist of a cascade of linear+nonlinear layers that modify the linear measurements at the retinal photo-receptors leading to an internal (nonlinear) representation of color that…

Neurons and Cognition · Quantitative Biology 2022-10-13 Jesus Malo

Given a discriminating neural network, the problem of fairness improvement is to systematically reduce discrimination without significantly scarifies its performance (i.e., accuracy). Multiple categories of fairness improving methods have…

Machine Learning · Computer Science 2022-09-16 Mengdi Zhang , Jun Sun

This paper considers multiple binary hypothesis tests with adaptive allocation of sensing resources from a shared budget over a small number of stages. A Bayesian formulation is provided for the multistage allocation problem of minimizing…

Methodology · Statistics 2014-11-05 Dennis Wei

Continuous, adaptive learning, the ability to adapt to the environment and keep improving performance, is a hallmark of natural intelligence. Biological organisms excel in acquiring, transferring, and retaining knowledge while adapting to…

Neurons and Cognition · Quantitative Biology 2026-03-03 Jie Mei , Alejandro Rodriguez-Garcia , Daigo Takeuchi , Gabriel Wainstein , Nina Hubig , Yalda Mohsenzadeh , Srikanth Ramaswamy

Many mathematical models of synaptic plasticity have been proposed to explain the diversity of plasticity phenomena observed in biological organisms. These models range from simple interpretations of Hebb's postulate, which suggests that…

Neurons and Cognition · Quantitative Biology 2025-08-05 Danil Tyulmankov

Brains have evolved diverse neurons with varying morphologies and dynamics that impact temporal information processing. In contrast, most neural network models use homogeneous units that vary only in spatial parameters (weights and biases).…

Neural and Evolutionary Computing · Computer Science 2025-01-14 Karim G. Habashy , Benjamin D. Evans , Dan F. M. Goodman , Jeffrey S. Bowers

Brain-inspired learning models attempt to mimic the cortical architecture and computations performed in the neurons and synapses constituting the human brain to achieve its efficiency in cognitive tasks. In this work, we present…

Neural and Evolutionary Computing · Computer Science 2017-03-21 Priyadarshini Panda , Gopalakrishnan Srinivasan , Kaushik Roy

Guided diffusion sampling relies on approximating often intractable likelihood scores, which introduces significant noise into the sampling dynamics. We propose using adaptive moment estimation to stabilize these noisy likelihood scores…

Machine Learning · Computer Science 2026-04-24 Christian Belardi , Justin Lovelace , Kilian Q. Weinberger , Carla P. Gomes
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